Monitoring conformational changes in the human neurotransmitter transporter homologue LeuT with 19F-NMR spectroscopy. [PDF]
J NeurochemFunding Information: We would like to thank Andreas Nygaard and Solveig G. Schmidt at the University of Copenhagen for providing us with technical support. Publisher Copyright: © 2024 The Author(s). Journal of Neurochemistry published by John Wiley &
Daminato A, Loland CJ, Cabrita EJ.
europepmc +3 more sources
Loop VIII/IX of the Na+-citrate transporter CitS of Klebsiella pneumoniae folds into an amphipathic surface helix [PDF]
, 2005 The sodium ion-dependent citrate transporter CitS of Klebsiella pneumoniae is a member of, the 2-hydroxycarboxylate transporter (2HCT) family whose members transport divalent citrate in symport with two sodium ions.
Lolkema, JS +2 more
core +5 more sources
Structural basis of proton-coupled potassium transport in the KUP family [PDF]
, 2020 Potassium homeostasis is vital for all organisms, but is challenging in single-celled organisms like bacteria and yeast and immobile organisms like plants that constantly need to adapt to changing external conditions.
Aumüller, Nadine +9 more
core +2 more sources
Quantitative description of ion transport via plasma membrane of yeast and small cells [PDF]
, 2015 Modeling of ion transport via plasma membrane needs identification and quantitative understanding of the involved processes. Brief characterization of main ion transport systems of a yeast cell (Pma1, Ena1, TOK1, Nha1, Trk1, Trk2, non-selective cation ...
Volkov, Vadim
core +6 more sources
Sodium-Assisted Formation of Binding and Traverse Conformations of the Substrate in a Neurotransmitter Sodium Symporter Model [PDF]
, 2014 Therapeutics designed to increase synaptic neurotransmitter levels by inhibiting neurotransmitter sodium sym- porters (NSSs) classify a strategic approach to treat brain disorders such as depression or epilepsy, however, the critical elementary steps ...
Bencsura, Ákos +4 more
core +1 more source
Plant High-Affinity Potassium (HKT) transporters involved in salinity tolerance: structural insights to probe differences in ion selectivity [PDF]
, 2013 High-affinity Potassium Transporters (HKTs) belong to an important class of integral membrane proteins (IMPs) that facilitate cation transport across the plasma membranes of plant cells.
Alberts +95 more
core +3 more sources
Phylogenetically Driven Sequencing of Extremely Halophilic Archaea Reveals Strategies for Static and Dynamic Osmo-response [PDF]
, 2014 © 2014. Organisms across the tree of life use a variety of mechanisms to respond to stress-inducing fluctuations in osmotic conditions. Cellular response mechanisms and phenotypes associated with osmoadaptation also play important roles in bacterial ...
Becker, EA +10 more
core +1 more source
Functional properties of a newly cloned fish ortholog of the neutral amino acid transporter B0AT1 (SLC6A19) [PDF]
, 2013 The functional properties of an ortholog of the B0AT1 (SLC6A19) amino acid transporter, cloned from the intestine of the sea bass Dicentrachus labrax, were investigated.
Antonio Peres +4 more
core +1 more source
The Jackprot Simulation Couples Mutation Rate with Natural Selection to Illustrate How Protein Evolution Is Not Random [PDF]
, 2011 Protein evolution is not a random process. Views which attribute randomness to molecular change, deleterious nature to single-gene mutations, insufficient geological time, or population size for molecular improvements to occur, or invoke “design ...
Bai, Chunyan Y. +2 more
core +2 more sources
A Single Amino-Acid Substitution in the Sodium Transporter HKT1 Associated with Plant Salt Tolerance [PDF]
, 2016 A crucial prerequisite for plant growth and survival is the maintenance of potassium uptake, especially when high sodium surrounds the root zone. The Arabidopsis HIGH-AFFINITY K(+) TRANSPORTER1 (HKT1), and its homologs in other salt-sensitive dicots ...
MAGGIO, ALBINO
core +3 more sources