Functional characterization of NRT1/PTR FAMILY transporters: looking for a needle in a haystack. [PDF]
New PhytolSummary NRT1/PTR FAMILY (NPF) transporters play crucial roles in plant physiology and development due to their involvement in nitrogen nutrition and their ability to transport multiple signaling molecules and metabolites. Whereas most eukaryotic and prokaryotic NPF orthologs are peptide transporters, most flowering plant NPF transport other substrates ...
Morales de Los Ríos L +6 more
europepmc +2 more sources
Thiazide-Induced Acute Interstitial Pancreatitis in a 55-Year-Old Male: A Rare Adverse Drug Reaction. [PDF]
Clin Case RepABSTRACT Acute pancreatitis is inflammation of the pancreas and is most commonly caused by gallstones, alcohol use, hyperlipidemia, or idiopathic. Drug‐induced acute pancreatitis is relatively rare and often under‐recognized; it accounts for 0.1%–2% of all cases. Among many drugs, thiazide diuretics are infrequently implicated but remain a known cause.
Pandey K +4 more
europepmc +2 more sources
Deciphering the Sodium Sensing Mechanisms in Glycophytes and Halophytes. [PDF]
Plant Cell EnvironABSTRACT Plants, including halophytes (salt‐tolerant) and glycophytes (salt‐sensitive), have developed diverse molecular mechanisms and morphological adaptations to survive in saline environments. The cellular components and molecular processes for salinity sensing and stress tolerance have been extensively identified in glycophytes, but not so with ...
Cheema RA +4 more
europepmc +2 more sources
Chloride in Heart Failure:The Neglected Electrolyte [PDF]
, 2021 The increasing burden of heart failure (HF) and emerging knowledge regarding chloride as a prognostic marker in HF have increased the interest in the pathophysiology and interactions of chloride abnormalities with HF-related factors and treatments ...
Ezekowitz, Justin A. +7 more
core +1 more source
Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+ site [PDF]
, 2018 Many pathogenic bacteria utilise sialic acids as an energy source or use them as an external coating to evade immune detection. As such, bacteria that colonise sialylated environments deploy specific transporters to mediate import of scavenged sialic ...
Abramson, Jeff, +21 more
core +3 more sources
Increased tolerance to salt stress in the phosphate-accumulating Arabidopsis mutants siz1 and pho2 [PDF]
, 2011 High salinity is an environmental factor thatinhibits plant growth and development, leading to largelosses in crop yields. We report here that mutations in SIZ1or PHO2, which cause more accumulation of phosphatecompared with the wild type, enhance ...
Furukawa Jun +5 more
core +1 more source
Ionic selectivity and thermal adaptations within the voltage-gated sodium channel family of alkaliphilic Bacillus [PDF]
, 2014 Entry and extrusion of cations are essential processes in living cells. In alkaliphilic prokaryotes, high external pH activates voltage-gated sodium channels (Nav), which allows Na+ to enter and be used as substrate for cation/proton antiporters ...
Clapham, David E +4 more
core +2 more sources
Ion transport through biological channels [PDF]
, 2015 The transport of ions across single-molecule protein nanochannels is important both in the biological context and in proposed nanotechnological applications.
Aguilella-Arzo, Marcel, Faraudo, Jordi
core +2 more sources
Anion-transport mechanism of a triazole-bearing derivative of prodigiosine: a candidate for cystic fibrosis therapy [PDF]
, 2018 Cystic fibrosis (CF) is a genetic lethal disease, originated from the defective function of the CFTR protein, a chloride and bicarbonate permeable transmembrane channel.
Baroni, Debora +7 more
core +2 more sources
Pharmacologic Properties of Proton Pump Inhibitors [PDF]
, 2003 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90231/1/phco.23.13.74S.31929 ...
Welage, Lynda S.
core +1 more source