Results 11 to 20 of about 27,903 (184)

Monitoring conformational changes in the human neurotransmitter transporter homologue LeuT with ¹⁹F-NMR spectroscopy. [PDF]

J Neurochem
Neurotransmitter:sodium symporters (NSS) reuptake neurotransmitter molecules from the synaptic space through Na+‐coupled transport. Much of the current knowledge about these transporters and the multiple configurations dictated by the binding of substrates and ions, has been derived from examining the structure of the Leucine Transporter (LeuT), a ...
Daminato A, Loland CJ, Cabrita EJ.
europepmc   +2 more sources

Chloride in Heart Failure:The Neglected Electrolyte [PDF]

, 2021
The increasing burden of heart failure (HF) and emerging knowledge regarding chloride as a prognostic marker in HF have increased the interest in the pathophysiology and interactions of chloride abnormalities with HF-related factors and treatments ...
Ezekowitz, Justin A., Julius, Florine E.C., McAlister, Finlay A., Pannu, Neesh, Sepehrvand, Nariman, van Norel, Margje R., Voors, Adriaan A., Zandijk, Arietje J.L.   +7 more
core   +1 more source

Structural basis of proton-coupled potassium transport in the KUP family [PDF]

, 2020
Potassium homeostasis is vital for all organisms, but is challenging in single-celled organisms like bacteria and yeast and immobile organisms like plants that constantly need to adapt to changing external conditions.
Aumüller, Nadine, Corey, Robin A., Griwatz, David, Hänelt, Inga, Mikusevic, Vedrana, Mills, Deryck J., Sousa, Joana S., Stansfeld, Phillip J., Tascón, Igor, Vonck, Janet   +9 more
core   +1 more source

Sodium-Assisted Formation of Binding and Traverse Conformations of the Substrate in a Neurotransmitter Sodium Symporter Model [PDF]

, 2014
Therapeutics designed to increase synaptic neurotransmitter levels by inhibiting neurotransmitter sodium sym- porters (NSSs) classify a strategic approach to treat brain disorders such as depression or epilepsy, however, the critical elementary steps ...
Bencsura, Ákos, Héja, László, Kardos, Julianna, Magyar, Csaba, Simon, Ágnes   +4 more
core   +1 more source

Functional properties of a newly cloned fish ortholog of the neutral amino acid transporter B0AT1 (SLC6A19) [PDF]

, 2013
The functional properties of an ortholog of the B0AT1 (SLC6A19) amino acid transporter, cloned from the intestine of the sea bass Dicentrachus labrax, were investigated.
Antonio Peres, Elena Bossi, Eleonora Margheritis, Genciana Terova, Raffaella Cinquetti   +4 more
core   +1 more source

Plant High-Affinity Potassium (HKT) transporters involved in salinity tolerance: structural insights to probe differences in ion selectivity [PDF]

, 2013
High-affinity Potassium Transporters (HKTs) belong to an important class of integral membrane proteins (IMPs) that facilitate cation transport across the plasma membranes of plant cells.
Alberts, Andersen, Ardie, Banuelos, Baxter, Berman, Berthomieu, Bolla, Bourguignon, Byrt, Cao, Chatelain, Corratgé-Faillie, Cotsaftis, Das, Davenport, Diatloff, Dubcovsky, Durell, Dvořak, Fairbairn, Farrokhi, Gabanyi, Garciadeblas, Gassmann, Geer, Genc, Gomez-Porras, Gregoire, Haferkamp, Haro, Hauser, Hedrich, Horie, Horie, Horie, Horie, Hrmova, Hu, Huang, Hunter, Ikeda, Ito, Jabnoune, Kato, Kato, Lan, Landau, Larkin, Laurie, Li, Liu, Luecke, Maathuis, Marassi, Maria Hrmova, Matthew Gilliham, Mondini, Munns, Munns, Mäser, Mäser, Møller, Møller, Nickerson, Nugent, Oomen, Periasamy, Platten, Plett, Plett, Raja, Ren, Rengasamy, Rosenbaum, Rubio, Rubio, Rus, Saitou, Sassi, Scalise, Schachtman, Schachtman, Schulze, Shane Waters, Souda, Spalding, Sunarpi, Tyerman, Uozumi, Walas, Walker, Wang, Yao, Zimmerli, Šali   +95 more
core   +3 more sources

Loop VIII/IX of the Na+-citrate transporter CitS of Klebsiella pneumoniae folds into an amphipathic surface helix [PDF]

, 2005
The sodium ion-dependent citrate transporter CitS of Klebsiella pneumoniae is a member of, the 2-hydroxycarboxylate transporter (2HCT) family whose members transport divalent citrate in symport with two sodium ions.
Lolkema, JS, Sobczak, [No Value], Sobczak, Iwona   +2 more
core   +5 more sources

Phylogenetically Driven Sequencing of Extremely Halophilic Archaea Reveals Strategies for Static and Dynamic Osmo-response [PDF]

, 2014
© 2014. Organisms across the tree of life use a variety of mechanisms to respond to stress-inducing fluctuations in osmotic conditions. Cellular response mechanisms and phenotypes associated with osmoadaptation also play important roles in bacterial ...
Becker, EA, Darling, AE, Eisen, JA, Facciotti, MT, Krusor, M, Larsen, D, Madern, D, Seitzer, PM, Tritt, A, Wu, D, Yao, AI   +10 more
core   +1 more source

Potassium Channel and NKCC Cotransporter Involvement in Ocular Refractive Control Mechanisms [PDF]

, 2008
Myopia affects well over 30% of adult humans globally. However, the underlying physiological mechanism is little understood. This study tested the hypothesis that ocular growth and refractive compensation to optical defocus can be controlled by ...
AV Dmitriev, AV Dmitriev, B Lei, B Rohrer, B Seet, BJ Curtin, BM Junghans, BM Junghans, BT Gabelt, C Wildsoet, D Ehrlich, David P. Crewther, DP Crewther, DP Crewther, H Liang, H Shimazaki, H Shimazaki, Huibert D. Mansvelder, J Wallman, J Wallman, JA Beresford, JB Park, JD Li, JL Edelman, JM Russell, JR Phillips, JS Adorante, KE Gavrikov, KE Gavrikov, M Marmor, Melanie J. Murphy, MM Civan, MT Pardue, N Vardi, RA Bello, RH Steinberg, RP Gallemore, S Grissmer, S Hamann, S Hamann, S Wimmers, SG Crewther, SG Crewther, Sheila G. Crewther, SJ Bakri, SJ Walter, T Krupin, T Pannicke   +47 more
core   +3 more sources

Quantitative description of ion transport via plasma membrane of yeast and small cells [PDF]

, 2015
Modeling of ion transport via plasma membrane needs identification and quantitative understanding of the involved processes. Brief characterization of main ion transport systems of a yeast cell (Pma1, Ena1, TOK1, Nha1, Trk1, Trk2, non-selective cation ...
Volkov, Vadim
core   +4 more sources