Results 21 to 30 of about 2,550 (106)

Characterization of acetate transport in colorectal cancer cells and potential therapeutic implications [PDF]

, 2016
Acetate, together with other short chain fatty acids has been implicated in colorectal cancer (CRC) prevention/therapy. Acetate was shown to induce apoptosis in CRC cells. The precise mechanism underlying acetate transport across CRC cells membrane, that
Baltazar, Baltazar, Baltazar, Baltazar, Baltazar, Bektasoglu, Bordonaro, Brenner, Broer, Butler, Cai, Carrasco, Casal, Casal, Casal, Clifton, Corte-Real, El-Rayes, Ganapathy, Ganapathy, Ganapathy, Gibson, Guan, Halestrap, Halestrap, Halestrap, Halestrap, Jan, Jan, Jaworski, Kim, Kimura, Kuwahara, Markowitz, Martel, Meredith, Moffett, Pedersen, Preto, Ramaswamy, Richter, Saadoun, Shirazi-Beechey, Shirazi-Beechey, Singh, Suematsu, Sun, Thangaraju, Thompson, Verkman, Verkman, Yasui, Young   +52 more
core   +1 more source

Molecular mechanism of ligand recognition by membrane transport protein, Mhp1 [PDF]

, 2014
The hydantoin transporter Mhp1 is a sodium-coupled secondary active transport protein of the nucleobase-cation-symport family and a member of the widespread 5-helix inverted repeat superfamily of transporters.
A Peter Johnson, Alexander D Cameron, Colin WG Fishwick, David Drew, David J Sharples, Ekaterina Ivanova, Florian Brueckner, Joseph Lanigan, Katie J Simmons, Mark SP Sansom, Oliver Beckstein, Peter JF Henderson, Scott M Jackson, Simon G Patching, Simone Weyand, So Iwata, Tian Geng, Zsoldos Z   +17 more
core   +4 more sources

An immature B cell population from peripheral blood serves as surrogate marker for monitoring tumor angiogenesis and anti-angiogenic therapy in mouse models [PDF]

, 2015
Tumor growth depends on the formation of new blood vessels (tumor angiogenesis) either from preexisting vessels or by the recruitment of bone marrow-derived cells.
Bill, Ruben, Christofori, Gerhard, Fagiani, Ernesta, Ivanek, Robert, Pisarsky, Laura, Rüegg, Curzio   +5 more
core   +1 more source

Astatine‐211—Towards In Vivo Stable Astatine‐211 Labeled Radiopharmaceuticals and Their (Pre)Clinical Applications

Medicinal Research Reviews, Volume 46, Issue 1, Page 203-237, January 2026.
ABSTRACT Targeted radioligand therapy has emerged as a promising treatment option for eradicating advanced cancer forms. α‐Emitters are considered particularly promising as they can obliterate (micro)‐metastases. The α‐emitter astatine‐211 (211At) has experienced increased interest due to its favorable decay properties.
Marius Müller, Nadia Bom Pedersen, Vladimir Shalgunov, Andreas Ingemann Jensen, Umberto Maria Battisti, Matthias Manfred Herth   +5 more
wiley   +1 more source

Potassium Channel and NKCC Cotransporter Involvement in Ocular Refractive Control Mechanisms [PDF]

, 2008
Myopia affects well over 30% of adult humans globally. However, the underlying physiological mechanism is little understood. This study tested the hypothesis that ocular growth and refractive compensation to optical defocus can be controlled by ...
AV Dmitriev, AV Dmitriev, B Lei, B Rohrer, B Seet, BJ Curtin, BM Junghans, BM Junghans, BT Gabelt, C Wildsoet, D Ehrlich, David P. Crewther, DP Crewther, DP Crewther, H Liang, H Shimazaki, H Shimazaki, Huibert D. Mansvelder, J Wallman, J Wallman, JA Beresford, JB Park, JD Li, JL Edelman, JM Russell, JR Phillips, JS Adorante, KE Gavrikov, KE Gavrikov, M Marmor, Melanie J. Murphy, MM Civan, MT Pardue, N Vardi, RA Bello, RH Steinberg, RP Gallemore, S Grissmer, S Hamann, S Hamann, S Wimmers, SG Crewther, SG Crewther, Sheila G. Crewther, SJ Bakri, SJ Walter, T Krupin, T Pannicke   +47 more
core   +3 more sources

Population Genomics Provides Novel Insights Into Evolutionary Relationships and Local Adaptation of Two Ecotypes Coilia nasus

Ecology and Evolution, Volume 15, Issue 12, December 2025.
Based on whole‐genome resequencing, we determined that the freshwater‐resident form (C. nasus taihuensis) is an ecotype of anadromous Coilia nasus, not a distinct subspecies. The two ecotypes diverged approximately 4.6 thousand years ago, coinciding with the formation of Tai Lake.
Fengjiao Ma, Sheng Wang, Wenzhi Ma, Hui Wang, Haotian Jin, Legen Peng, Guojun Yin, Kai Liu   +7 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Introduction and Other Protein Targets

British Journal of Pharmacology, Volume 182, Issue S1, Page S1-S23, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, John A. Cidlowski, Anthony P. Davenport, Doriano Fabbro, Michael Spedding, Jörg Striessnig, Jane F. Armstrong, O. Peter Buneman, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Katelin E. Ahlers‐Dannen, Mohammed Alqinyah, Thiruma V. Arumugam, Christopher Bodle, Josephine Buo Dagner, Bandana Chakravarti, Shreoshi P. Choudhuri, Kirk M. Druey, Rory A. Fisher, Kyle J. Gerber, John R. Hepler, Shelley B. Hooks, Havish S. Kantheti, Behirda Karaj, Somayeh Layeghi‐Ghalehsoukhteh, Jae‐Kyung Lee, Zili Luo, Kirill Martemyanov, Luke D. Mascarenhas, Harrison McNabb, Carolina Montañez‐Miranda, Osita Ogujiofor, Hoa Phan, David L. Roman, Vincent Shaw, Benita Sjogren, Christopher Sobey, Mackenzie M. Spicer, Katherine E. Squires, Laurie Sutton, Menbere Wendimu, Thomas Wilkie, Keqiang Xie, Qian Zhang, Yalda Zolghadri   +51 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Transporters

British Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Laura Amarosi, Catriona M. H. Anderson, Philip M. Beart, Stefan Broer, Paul A. Dawson, Gergely Gyimesi, Bruno Hagenbuch, James R. Hammond, Jules C. Hancox, Michal Hershfinkel, Ken‐ichi Inui, Yoshikatsu Kanai, Stephan Kemp, Edmund R. S. Kunji, Gavin Stewart, Sotiria Tavoulari, David T. Thwaites, Tiziano Verri   +28 more
wiley   +1 more source

Impact of Sodium Chloride and Heat on Survival Time of Linguatula Serrata Nymphs in vitro: An Experimental Study

Journal of Community Health Research, 2012
Introduction: Linguatula serrata is a zoonotic parasite, belonging to the class Pentastomida. The major aim of this study was to evaluate the impact of sodium chloride (NaCl) and heat on survival time of Linguatula serrata nymphs.
B. Hajimohammadi, A. Akhondzadeh Basti, S. Shirali   +2 more
doaj  

Iodine biofortification of crops: agronomic biofortification, metabolic engineering and iodine bioavailability [PDF]

, 2017
Iodine deficiency is a widespread micronutrient malnutrition problem, and the addition of iodine to table salt represents the most common prophylaxis tool.
Gonzali, Silvia, Kiferle, Claudia, Perata, Pierdomenico   +2 more
core   +1 more source