Results 11 to 20 of about 6,765 (157)

Association between a novel G94A single nucleotide polymorphism in ATP1A1 gene and type 2 diabetes mellitus among Egyptian patients

Journal of Research in Medical Sciences, 2019
Background: Na+/K+ ATPase enzyme is essential for nerve cell membrane integrity, and reduction in its activity, probably due to ATP1A1 gene polymorphisms, is related to diabetic neuropathy progression.
Mohammed A Abosheasha, Faten Zahran, Sahar S Bessa, Mohammed A El-Magd, Tarek M Mohamed   +4 more
doaj   +1 more source

Sublethal salinity stress contributes to habitat limitation in an endangered estuarine fish. [PDF]

, 2016
As global change alters multiple environmental conditions, predicting species' responses can be challenging without understanding how each environmental factor influences organismal performance.
Connon, Richard E, Dexter, Jason, Fangue, Nann A, Hasenbein, Matthias, Jeffries, Ken M, Komoroske, Lisa M, Verhille, Christine   +6 more
core   +1 more source

The Slow Dynamics of Intracellular Sodium Concentration Increase the Time Window of Neuronal Integration: A Simulation Study

Frontiers in Computational Neuroscience, 2017
Changes in intracellular Na+ concentration ([Na+]i) are rarely taken into account when neuronal activity is examined. As opposed to Ca2+, [Na+]i dynamics are strongly affected by longitudinal diffusion, and therefore they are governed by the ...
Asaph Zylbertal, Yosef Yarom, Shlomo Wagner   +2 more
doaj   +1 more source

Genomic and non-genomic effects of a new sodium-sensing network in renal and lung epithelia [PDF]

, 2012
Sodium and water homeostasis is crucial for cell function, survival and health of the individual. The kidney is responsible for sodium regulation in the body, balancing sodium secretion and reabsorption, and thereby also regulating the blood pressure,
Eneling, Kristina
core   +1 more source

Greasing the wheels or a spanner in the works?:Regulation of the cardiac sodium pump by palmitoylation [PDF]

, 2018
The ubiquitous sodium/potassium ATPase (Na pump) is the most abundant primary active transporter at the cell surface of multiple cell types, including ventricular myocytes in the heart.
Fiona Plain, Jacqueline Howie, Kakar SS, Krzysztof J. Wypijewski, Lindsay B. Tulloch, Mullins LJ., Niall J. Fraser, Pitts BJ, Presti CF, Presti CF, William Fuller   +10 more
core   +3 more sources

Coronatine-insensitive 1 (COI1) mediates transcriptional responses of Arabidopsis thaliana to external potassium supply [PDF]

, 2010
The ability to adjust growth and development to the availability of mineral nutrients in the soil is an essential life skill of plants but the underlying signaling pathways are poorly understood.
Abe, Amtmann, Amtmann, Amtmann, Amtmann, Amtmann, Amtmann, Amtmann, Armengaud, Armengaud, Ashley, Balbi, Bednarek, Bolstad, Breitling, Breitling, Cao, Chung, Creelman, Devoto, Devoto, Dobermann, Epstein, Evans, Geisler, He, Hull, Jung, Kafkafi, Kim, Laegreid, Li, Maathuis, Maathuis, Marschner, Mikkelsen, Munemasa, Nakano, Okushima, Oria-Hernandez, Otterhag, Pandey, Penninckx, Perez-Amador, Reinbothe, Reymond, Ross, Schachtman, Shin, Shin, Sparla, Staswick, Staswick, Staswick, Sun, Syers, Thines, Tschoep, Vernoud, Véry, Walker, Westphal, Xie, Xu, Yamaguchi-Shinozaki, Yan, Zimmermann   +66 more
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Mathematical Model of Ammonia Handling in the Rat Renal Medulla [PDF]

, 2015
The kidney is one of the main organs that produces ammonia and release it into the circulation. Under normal conditions, between 30 and 50% of the ammonia produced in the kidney is excreted in the urine, the rest being absorbed into the systemic ...
Baigent, S, Jalan, R, Noiret, L, Thomas, SR   +3 more
core   +1 more source

The Concise Guide to PHARMACOLOGY 2015/16:Transporters [PDF]

, 2015
The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org),
Aldrich, R, Alexander, SPH, Attali, B, Back, M, Barnes, NM, Bathgate, R, Beart, PM, Becirovic, E, Benson, HE, Biel, M, Birdsall, NJ, Boison, D, Brauner-Osborne, H, Broeer, S, Bryant, C, Burnstock, G, Burris, T, Cain, D, Calo, G, Chan, SL, Chandy, KG, Chiang, N, Christakos, S, Christopoulos, A, Chun, JJ, Chung, J-J, Clapham, DE, Connor, MA, Coons, L, Cox, HM, Dautzenberg, FM, Davies, JA, Dent, G, Douglas, SD, Dubocovich, ML, Edwards, DP, Faccenda, E, Farndale, R, Fong, TM, Forrest, D, Fowler, CJ, Fuller, P, Gainetdinov, RR, Gershengorn, MA, Goldin, A, Goldstein, SAN, Grimm, SL, Grissmer, S, Gundlach, AL, Hagenbuch, B, Hammond, JR, Hancox, JC, Hartig, S, Hauger, RL, Hay, DL, Hebert, T, Hollenberg, AN, Holliday, ND, Hoyer, D, Ijzerman, AP, Inui, KI, Ishii, S, Jacobson, KA, Jan, LY, Jarvis, GE, Jensen, R, Jetten, A, Jockers, R, Kaczmarek, LK, Kanai, Y, Kang, HS, Karnik, S, Kelly, E, Kerr, ID, Korach, KS, Lange, CA, Larhammar, D, Leeb-Lundberg, F, Leurs, R, Lolait, SJ, Macewan, D, Maguire, JJ, Marrion, N, May, JM, Mazella, J, McArdle, CA, McDonnell, DP, Michel, MC, Miller, LJ, Mitolo, V, Monie, T, Monk, PN, Mouillac, B, Murphy, PM, Nahon, J-L, Nerbonne, J, Nichols, CG, Norel, X, Oakley, R, Offermanns, S, Palmer, LG, Panaro, MA, Pawson, AJ, Perez-Reyes, E, Pertwee, RG, Peters, JA, Pike, JW, Pin, JP, Pintor, S, Plant, LD, Poyner, DR, Prossnitz, ER, Pyne, S, Ren, D, Richer, JK, Rondard, P, Ross, RA, Sackin, H, Safi, R, Sanguinetti, MC, Sartorius, CA, Segaloff, DL, Sharman, JL, Sladek, FM, Southan, C, Stewart, G, Stoddart, LA, Striessnig, J, Summers, RJ, Takeda, Y, Tetel, M, Toll, L, Trimmer, JS, Tsai, M-J, Tsai, SY, Tucker, S, Usdin, TB, Vilargada, J-P, Vore, M, Ward, DT, Waxman, SG, Webb, P, Wei, AD, Weigel, N, Willars, GB, Winrow, C, Wong, SS, Wulff, H, Ye, RD, Young, M, Zajac, J-M   +150 more
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The yeast F1-ATPase beta subunit precursor contains functionally redundant mitochondrial protein import information [PDF]

, 1987
The NH2 terminus of the yeast F1-ATPase beta subunit precursor directs the import of this protein into mitochondria. To define the functionally important components of this import signal, oligonucleotide-directed mutagenesis was used to introduce a ...
Bedwell, David M., Emr, Scott D., Klionsky, Daniel J.   +2 more
core   +1 more source

Measurement of (15)N longitudinal relaxation rates in (15)NH4(+) spin systems to characterise rotational correlation times and chemical exchange. [PDF]

, 2017
Many chemical and biological processes rely on the movement of monovalent cations and an understanding of such processes can therefore only be achieved by characterising the dynamics of the involved ions.
Hansen, DF
core   +1 more source