Results 41 to 50 of about 4,001 (111)

Glycative Stress Disrupts the Mitochondrial‐Lysosome Axis and Promotes Geroconversion in Aging Cardiomyocytes

Aging Cell, Volume 25, Issue 3, March 2026.
Cardiac aging promotes mitochondrial AGE accumulation driven by defective glycative stress detoxification. AGE‐modified mitochondria disrupt lysosomal proteolysis, impairing mitophagy and promoting lipofuscin buildup. This mechanism sustains chronic unresolved mitochondrial damage, driving proinflammatory senescence in cardiomyocytes and defining a ...
Diana Bou‐Teen, Simonas Valiuska, Elisabet Miro‐Casas, Chiara Rubeo, Elena Bonzon‐Kulichenko, Zuzana Nichtova, Celia Fernandez‐Sanz, Javier Inserte, Antonio Rodriguez‐Sinovas, Begoña Benito, Eduard Ródenas‐Alesina, Jesús Vázquez, Ignacio Ferreira‐González, Marisol Ruiz‐Meana   +13 more
wiley   +1 more source

Treg cells retain stable lineage commitment during pregnancy in mice after late gestation inflammatory challenge

Immunology &Cell Biology, Volume 104, Issue 3, Page 276-311, March 2026.
In this study, we used Foxp3‐fatemapping mice to examine the cell lineage stability of Treg cells in pregnancy. Ex‐Foxp3 cells were identified in gestational tissues. However, Treg cells retained lineage stability with no increased ex‐Foxp3 generation, regardless of inflammatory challenges that induce preterm birth.
Kerrie L Foyle, Ella S Green, Jessie R Walker‐Rogers, Ha M Tran, David M Olson, Lachlan M Moldenhauer, Sarah A Robertson   +6 more
wiley   +1 more source

Therapeutic efficacy of Annona muricata in counteracting nephrolithiasis-induced electrolyte imbalance and antioxidant disruption in ethylene glycol-treated rats. [PDF]

Sci Rep
Rahman SA, Sulaimon LA, Arogundade OL, Osifade OA, Akinolye OA.   +4 more
europepmc   +1 more source

Mechanism of action of cisplatin on Na+/K+ ATPase of Caco-2 colon cells in vitro. [PDF]

PLoS One
Mourad R, Hodeify R, Kreydiyyeh S.
europepmc   +1 more source

Elevated Na⁺/K⁺ Ratio in Alzheimer's Disease: A Potential Biomarker for Braak Stage. [PDF]

Int J Mol Sci
Mizuno Y, Pan S, Zhou T, Kehoe PG, Feng Earley Y.   +4 more
europepmc   +1 more source

The electrogenicity of the Na⁺/K⁺-ATPase poses challenges for computation in highly active spiking cells. [PDF]

Elife
Weerdmeester L, Schleimer JH, Schreiber S.   +2 more
europepmc   +1 more source

Inflammatory Co-Regulation of Voltage-Gated Sodium Channels and Na,K-ATPase in Metastatic Breast Cancer. [PDF]

Int J Mol Sci
Scahill SD, Sherman KJ, Paul D.
europepmc   +1 more source

The Na/K-ATPase α1 subunit fine-tunes platelet P2Y12 function and mediates sex dimorphism-associated thrombosis. [PDF]

Blood Adv
Li OQ, Yue H, DeHart AR, Roytenberg R, Li AY, Bai F, Su H, Aguilar R, Olanipekun O, Liu J, Fedorova OV, Kennedy D, Thompson E, Shavit JA, Pierre SV, Li W.   +15 more
europepmc   +1 more source

Alterations in renal Na,K-ATPase activity and protein expression in rat models of pressure and volume overload. [PDF]

Sci Rep
Vrbjar N, Ondrejak Andelova K, Sykora M, Kovacicova I, Snurikova D, Cervenka L, Radosinska J, Szeiffova Bacova B.   +7 more
europepmc   +1 more source

Mechanisms of impaired glucose transport in cryptosporidiosis in goat kids. [PDF]

BMC Vet Res
Krasilnikova V, Kuzmina E, Philippova A.
europepmc   +1 more source