Results 51 to 60 of about 6,765 (157)

The Galleria mellonella Hologenome Supports Microbiota-Independent Metabolism of Long-Chain Hydrocarbon Beeswax [PDF]

, 2019
The greater wax moth, Galleria mellonella, degrades wax and plastic molecules. Despite much interest, the genetic basis of these hallmark traits remains poorly understood. Herein, we assembled high-quality genome and transcriptome data from G. mellonella
Albertsson, Albertsson, Albertsson, Ammala, Aronson, Artham, Attwood, Bairoch, Benson, Benson, Besemer, Brandon, Bru, Buffie, Burges, Camacho, Cantarel, Capella-Gutiérrez, Ceja-Navarro, Chevallier, Chin, Downs, Edgar, El Aidy, Ferdinandusse, Freed, Gary, Gatter, Grabherr, Han, Hillman, Houten, Hsiao, Huang, Hulo, Huson, Jones, Jurka, Kambhampati, Kent, Kim, Kim, Klein, Korf, Kumar, Kwadha, Labandeira, Larkin, Li, Li, Li, Mahdiyah, Majoros, Martel, McFall-Ngai, Mi, Moriya, Nkwachukwu, Nowack, Oaxaca-Castillo, Ohtake, Oldroyd, Oldroyd, Ortiz de Montellano, Parra, Pathak, Pegram, Ponting, Price, Punta, Qu, Ramarao, Regert, Roberts, Rowland, Roy, Shah, Shao, Simão, Singh, Slater, St Pierre, Stamatakis, Stanke, Tokiwa, Trapnell, Tulloch, Wilkes, Wu, Xia, Yang, Yang, Yang, Yang, Yang, Yang, Zdobnov, Zettler, Zhang   +98 more
core   +1 more source

14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses

The Journal of Physiology, EarlyView.
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley   +1 more source

Sulfate transporters involved in sulfate secretion in the kidney are localized in the renal proximal tubule II of the elephant fish (Callorhinchus milii)

, 2016
Most vertebrates, including cartilaginous fishes, maintain their plasma SO4 (2-) concentration ([SO4 (2-)]) within a narrow range of 0.2-1 mM. As seawater has a [SO4 (2-)] about 40 times higher than that of the plasma, SO4 (2-) excretion is the major ...
Bell, Justin D., Donald, John A., Hasegawa, Kumi, Hyodo, Susumu, Kato, Akira, Romero, Michael F., Takagi, Wataru, Toop, Tes, Watanabe, Taro   +8 more
core   +1 more source

Cellular mechanisms of radiation‐induced myocyte dysfunction: effects on calcium handling, ion channel regulation and mitochondrial energetics

The Journal of Physiology, EarlyView.
Abstract figure legend Dose‐dependent effects of radiation on cardiac electrophysiology and arrhythmia susceptibility. At low radiation doses (left), increased reactive oxygen species (ROS) initiate an ROS–Ca2+ positive feedback loop involving calcium/calmodulin‐dependent protein kinase II (CaMKII) activation, enhanced L‐type Ca2+ current (ICaL ...
Hannah M. Zukowski, Colleen E. Clancy
wiley   +1 more source

Overexpression of UCP1 in tobacco induces mitochondrial biogenesis and amplifies a broad stress response [PDF]

, 2014
Background: Uncoupling protein one (UCP1) is a mitochondrial inner membrane protein capable of uncoupling the electrochemical gradient from adenosine-5'-triphosphate (ATP) synthesis, dissipating energy as heat.
Ivan de Maia, Izabella Agostinho Neshich, Paulo Arruda, Pedro Barreto, Vagner Okura   +4 more
core   +5 more sources

Human‐derived cardiac‐neural microtissues reveal catecholaminergic polymorphic ventricular tachycardia is also a disease of the sympathetic neuron

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic diagram illustrating the proposed pathway in which regulatory defects might occur in sympathetic neurons derived from hiPSC in catecholaminergic polymorphic ventricular tachycardia (CPVT). Specifically, enhanced calcium transients appeared to derive from three sources: enhanced membrane excitability (due to loss of ...
Ni Li, Chenchen Zhang, Mengying Xu, YoonYoung Choi, Davi Sidarta‐Oliveira, Ruirui Dong, Xinyu Hu, Enrique M. Toledo, Cesar A. Prada‐Medina, Finbar Argus, Kun Liu, Mingyu Li, Linna Zhou, Hagan Bayley, Corey Smith, Chris Denning, Ana I. Domingos, Guoliang Hao, Dan Li, David J. Paterson   +19 more
wiley   +1 more source

FUNCTIONAL AND BIOCHEMICAL CONSEQUENCES OF SINGLE NUCLEOTIDE POLYMORPHISMS IN THE HUMAN VESICULAR MONOAMINE TRANSPORTER 1 GENE (SLC18A1) By Sally Gamal Shukry, B.S. [PDF]

, 2012
FUNCTIONAL AND BIOCHEMICAL CONSEQUENCES OF SINGLE NUCLEOTIDE POLYMORPHISMS IN THE HUMAN VESICULAR MONOAMINE TRANSPORTER 1 GENE (SLC18A1) By Sally Gamal Shukry, B.S. A thesis submitted in partial fulfillment of the requirements for the degree of Master of
Shukry, Sally Gamal
core   +1 more source

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

The Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise, Qinglu Li, Mary G. Garry   +2 more
wiley   +1 more source

Age‐ and sex‐specific modulation of human cardiac electrophysiology by doxorubicin

The Journal of Physiology, EarlyView.
Abstract figure legend DOX differentially impacts cardiac electrophysiology based on sex and age. Sex differences were primarily observed among younger hearts, where action potential duration (APD) prolongation was observed in females, but not in males. Created using BioRender. George, S. (2026) https://BioRender.com/wresf1k Abstract Acute doxorubicin (
Sharon A. George, Amber V. Mills, Erin O'Neill, Sofian N. Obaid, Igor R. Efimov, Tatiana Efimova   +5 more
wiley   +1 more source

American Thyroid Association Guide to Investigating Thyroid Hormone Economy and Action in Rodent and Cell Models [PDF]

, 2014
Background: An in-depth understanding of the fundamental principles that regulate thyroid hormone homeostasis is critical for the development of new diagnostic and treatment ap-proaches for patients with thyroid disease.
Antonio C. Bianco, Apostolopoulos JJ, Balázs Gereben, Bernier-Valentin F, Bianco AC, Bianco AC, Bianco AC, Biddinger P, Brian W. Kim, Brooker G, Carey MF, Cawthorne C, David S. Sharlin, Delverdier M, Dolphin PJ, Dolphin PJ, Douglas Forrest, Escobar del Rey F, Everts ME, Forrest D, Freitas FRS, Frumess RD, Galbraith DW, Goodman MN, Graham R. Williams, Grant Anderson, Grewal A, Harper ME, Hilditch TE, Kaplan MM, Kasuga Y, Kirschbaum BJ, Kopp P, Larsen PR, Lazar MA, Leonard JL, Maria Jesus Obregon, Mebis L, Morreale de Escobar G, Morreale de Escobar G, Muller A, Nilsson M, Nilsson M, Nunes MT, Pantos C, Pappas M, Pazos-Moura CC, Pennock GD, Peter A. Kopp, Refetoff S, Ring GC, Robin P. Peeters, Roy E. Weiss, Samuel Refetoff, Sap J, Sato M, Sellers EA, Sharifi J, Silva JE, Silva JE, Simonides WS, Sjöberg M, Smith QR, Taylor CR, Valerie Anne Galton, Visser TJ, Wagschal A, Warner S. Simonides, Wu SY, Xiao Hui Liao, Yen PM, Young JB, Zuckier LS   +72 more
core   +2 more sources