Results 61 to 70 of about 9,198 (161)

Encephalopathy: Cause, Pathogenesis, and Treatment

MedComm, Volume 7, Issue 6, June 2026.
Various encephalopathies (sepsis‐associated, hepatic, hypoxic–ischemic, diabetic, uremic, toxic) have incompletely elucidated pathogenesis, which severely restricts targeted therapy development. Small molecule drugs show unique multitarget potential but face toxicity, poor blood–brain barrier penetration and unclear specificity.
Shimeng Lv, Xia Zhong, Ruirui Shang, Linghui Kong, Yufei Huang, Yuexiang Ma, Jing Teng, Sheng Wei   +7 more
wiley   +1 more source

-ATPase in sorghum roots as affected by potassium deficiency and nitrogen sources

, 2014
We studied the influence of inorganic nitrogen sources (NO3 - or NH4 +) and potassium deficiency on expression and activity of plasma membrane (PM) H+-ATPase in sorghum roots.
J. C. Alvarez-Pizarro, M. F. Grossi-De-Sá, O. B. De Oliveira-Neto, E. Gomes-Filho, R. Da Rocha Fragoso, J. T. Prisco   +5 more
core   +1 more source

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 12, Issue 3, Page 362-373, June 2026.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li, Yue Li, Yan‐Jie Jiang, Ge‐Hua Zhang, Li‐Hong Chang   +4 more
wiley   +1 more source

The polarized expression of Na+,K+-ATPase in epithelia depends on the association between beta-subunits located in neighboring cells

, 2005
The polarized distribution of Na+,K+-ATPase plays a paramount physiological role, because either directly or through coupling with co- and countertransporters, it is responsible for the net movement of, for example, glucose, amino acids, Ca2+, K+, Cl ...
Shoshani, L, Balda, MS, Cereijido, M, Matter, K, Moreno, J, Contreras, RG, Roldan, ML, Lazaro, A   +7 more
core  

Ion activities and potassium uptake mechanisms of glial cells in guinea-pig olfactory cortex slices. [PDF]

, 1987
1. Double-barrelled ion-sensitive micro-electrodes were used to measure changes in the intracellular activities of K+, Na+ and Cl- (aiK, aiNa, aiCl) in glial cells of slices from guinea-pig olfactory cortex during repetitive stimulation of the lateral ...
Ballanyi, Klaus, Ten Bruggencate, Gerrit, Grafe, Peter   +2 more
core  

Magnesium as a Bioenergetic Checkpoint Linking Mitochondrial Function, Metabolic Disease, and Aging

Aging Cell, Volume 25, Issue 6, June 2026.
This review positions magnesium as a central bioenergetic checkpoint that orchestrates mitochondrial function and metabolic resilience. By defining the functional ATP pool and stabilizing mitochondrial performance, magnesium homeostasis serves as a mechanistic link between renal handling, metabolic disease, and the aging process.
Chien‐Wei Huang, Chen‐Yueh Wen, Andy P. Tsai, Boyang Wang, Kuan‐Hao Tsui, Yu‐Juei Hsu, Chia‐Jung Li   +6 more
wiley   +1 more source

An investigation using cultured human cell lines, of the involvement of vanadium, cation transport and phosphatidylinositol in the aetiology of bipolar manic-depressive psychosis

, 2015
The symptoms, classification, occurrence and possible aetiologies of bipolar manic-depressive psychosis have been reviewed, with particular emphasis on the possible role of the vanadate ion (V5+) and cation transport in the illness.
Banks, Rosamonde Elizabeth, Naylor, Graham   +1 more
core  

ATPase activity of kidney mitochondria stimulated by sodium

, 1975
ATPase activity of intact mitochondria may be induced by the presence of sodium. Mitochondria obtained from kidney cortex or medulla demonstrate a higher sodium-stimulated ATPase than mitochondria prepared from liver.
MW Weiner
core   +1 more source

Sodium chloride transport of normal and dietary enlarged rat cecum in vitro [PDF]

, 1998
Sodium chloride transport across isolated cecum mucosa was investigated in normal rats and rats with adaptive cecum growth induced by dietary polyethylene glycol (PEG). The normal cecum absorbed CI in excess of Na with a small short-circuit current (Isc).
Schreiner, Josefine, Weber, Matthias, Loeschke, Klaus   +2 more
core   +1 more source

Higher sensitivity to ouabain‐induced toxicity in human induced pluripotent stem cell‐derived cardiomyocytes than human adult heart tissue despite similar Na+/K+‐ATPase pump current amplitudes

British Journal of Pharmacology, Volume 183, Issue 11, Page 3093-3110, June 2026.
Abstract Background and Purpose Human induced pluripotent stem cell‐derived cardiomyocytes (hiPSC‐CM) have gained interest as a pharmacological model but their immaturity leads to uncertainty regarding translation. We studied the key player in maintaining ionic homeostasis, the Na+/K+‐ATPase (NKA), in hiPSC‐CM.
Djemail Ismaili, Paavo Virtanen, Junsoo Im, Paul Brunnbauer, Umber Saleem, Muhammed Ikbal Sönmez, Carl Schulz, Margaret Nandudu, Joris Winters, Cristina E. Molina, Johannes Petersen, Monika Stoll, Ulrich Schotten, Arne Hansen, Thomas Eschenhagen, Jussi T. Koivumäki, Torsten Christ   +16 more
wiley   +1 more source