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Sodium is the major cation of extracellular fluid (ECF) and, because of its osmotic action, is involved in the regulation of ECF volume and blood pressure. The ingested sodium is almost completely absorbed by the intestine. Circulating sodium is filtered by the glomeruli and its renal tubular handling is responsible for the maintenance of sodium and ...
Pasquale Strazzullo, Veronica Abate
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Renal sodium handling and sodium sensitivity
The pathophysiology of hypertension, which affects over 1 billion individuals worldwide, involves the integration of the actions of multiple organ systems, including the kidney. The kidney, which governs sodium excretion via several mechanisms including pressure natriuresis and the actions of renal sodium transporters, is central to long term blood ...
Alissa A. Frame, Richard D Wainford
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Mixed Alkali Effect on Viscosity of Sodium Potassium Borate Glasses [PDF]
The effect of the alkali oxide content on viscosity has been studiedfor sodium-potassium borate glasses. The deviation of viscosity values fromadditivity has been modeled to investigate the effect of partial substitutionof one alkali oxide for another ...
Saad B. H. Farid
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Screening of Chickpea (Cicer arietinum L.) Genotypes for Salinity Tolerance at Early Growth Stages [PDF]
IntroductionChickpea is an important source of energy and protein of the Iranian people’s diet. Iran is one of the main centers of genetic diversity of this crop.
Narges Safaei Ghalehzou +3 more
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Eight five-month-old male lambs received a diet with marginal levels of sodium (0.5 g Na/kg DM); four lambs were given a single dose of infective Haemonchus contortus larvae (4,600 L3/ head) and four were kept uninfected.
Enrico Lippi Ortolani
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Background In vitro studies suggest that nephron nitric oxide synthase 3 (NOS3) modulates tubule Na+ transport. Methods and Results To assess nephron NOS3 relevance in vivo, knockout (KO) mice with doxycycline‐inducible nephron‐wide deletion of NOS3 were
Yang Gao +3 more
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Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
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Sodium Taste During Sodium Appetite [PDF]
Sodium appetite appears to be an excellent model to study the neural mechanisms of motivation. In this issue of Chemical Senses, experiments by St John (2016) challenge 2 hypotheses for how a systemic sodium deficit guides an animal to find and ingest more Na ions in the environment.
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Cardiovascular Diseases Deaths Attributable to High Sodium Intake in Shandong Province, China
Background High sodium intake elevates blood pressure and thereby raises cardiovascular diseases (CVDs). Sodium intake is high in northern China, including Shandong province where the SMASH (Shandong‐Ministry of Health Action on Sodium and Hypertension ...
Jiyu Zhang +6 more
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C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi +5 more
wiley +1 more source

