Results 41 to 50 of about 2,029,470 (268)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Freshwater, vital for life and ecosystems, accounts for only 2.5% of Earth’s water, and is primarily located in polar caps, underground reservoirs, and surface water.
Eduardo de Miguel-García +1 more
doaj +1 more source
Alkali activated fly ash binders. A comparative study between sodium and potassium activators
This paper shows the effect of the nature of some alkaline activators in the microstructural development of thermal-alkali activated f/y ash systems. The alkaline compounds employed in this investigation were: NaOH, KOH, Na2C03, K2C03, sodium silicate ...
A. Fernández-Jiménez +2 more
doaj +1 more source
Objective: The effect of processed foods on atopic dermatitis (AD) in adults is unclear. This study was to evaluate the association between processed foods and AD in the Chinese adult population.Design: This study included three population-based cross ...
Yajia Li +11 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The Toxic Effect of Lanthanum on Planaria Is Mediated by a Variety of Ion Channels
The effect of toxic concentrations of La3+ on the Ca, K, Na, Mg, and Cl channels of planaria was investigated through the use of various agonists and antagonists to those channels.
Wayne Briner
doaj +1 more source
Fenchone, a monoterpene: Toxicity and diuretic profiling in rats
Fenchone is a monoterpene present in the essential oils of various plants, including Foeniculum vulgare and Peumus boldus. Previous studies confirmed the anti-inflammatory, antioxidant, wound-healing, antidiarrheal, antifungal, antinociceptive, and ...
Asifa Bashir +3 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Background: Sodium homeostasis disruption is a fundamental pathophysiological mechanism in kidney diseases that critically affects the progression of renal dysfunction and the development of cardiovascular complications.
Anatoliy Gozhenko +4 more
doaj +1 more source
Case report of hypotonic dehydration with outcome in cerebral edema in a child
Dehydration is one of the most common disorders of water and electrolyte metabolism in young children. The reasons leading to the lack of water in the child’s body are very diverse.
Z. G. Tarasova +2 more
doaj +1 more source

