Results 61 to 70 of about 3,811,645 (309)

Pathophysiological Role of Sodium in Acute Kidney Injury and Chronic Kidney Disease: A Narrative Review

Journal of Education, Health and Sport
Background: Sodium homeostasis disruption is a fundamental pathophysiological mechanism in kidney diseases that critically affects the progression of renal dysfunction and the development of cardiovascular complications.
Anatoliy Gozhenko, Walery Zukow, Olena Gozhenko, Dmytro Ivanov, Oleksandr Vitiukov   +4 more
doaj   +1 more source

Fenchone, a monoterpene: Toxicity and diuretic profiling in rats

Frontiers in Pharmacology, 2023
Fenchone is a monoterpene present in the essential oils of various plants, including Foeniculum vulgare and Peumus boldus. Previous studies confirmed the anti-inflammatory, antioxidant, wound-healing, antidiarrheal, antifungal, antinociceptive, and ...
Asifa Bashir, Muhammad Naveed Mushtaq, Waqas Younis, Irfan Anjum   +3 more
doaj   +1 more source

Sodium modeling

Kidney International, 2000
The most serious side effects induced by hemodialysis therapy are caused by changes in sodium concentration and subsequent water shift between the intracellular and extracellular fluid compartment. Because of inadequate precision of proportioning, a certain sodium concentration and considerable error in the measurement of sodium concentration in ...
Mann, Helmut, Stiller, Siegfried
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Comprehensive Assessment of Correlation of Copeptin with Some Electrolytes in Adult Patients with Chronic Kidney Disease in Babylon Governorate

Medical Journal of Babylon
Background: Chronic kidney disease (CKD) is a rapidly expanding public health problem typified by either an increased excretion of albumin in the urine, a reduced glomerular filtration rate, or both.
Rawaa G. Abdullah, Manal F. Al-Khakani, Qasim Jawad Al-Daami   +2 more
doaj   +1 more source

The Effect of Salt Reduction on Sensory, Physicochemical, and Microbial Quality in Selected Meat Products

Foods
Efforts to reduce sodium chloride levels in meat products within the European Union are closely aligned with the World Health Organization’s recommendation to limit daily sodium intake to a maximum of 5 g per person.
Miroslav Jůzl, Josef Kameník, Alena Saláková, Blanka Macharáčková, František Ježek, Markéta Janík Piechowiczová, Jan Slováček   +6 more
doaj   +1 more source

LETM1-Mediated K+ and Na+ Homeostasis Regulates Mitochondrial Ca2+ Efflux

Frontiers in Physiology, 2017
Ca2+ transport across the inner membrane of mitochondria (IMM) is of major importance for their functions in bioenergetics, cell death and signaling. It is therefore tightly regulated.
Shane Austin, Mojtaba Tavakoli, Christina Pfeiffer, Julia Seifert, Andrea Mattarei, Diego De Stefani, Mario Zoratti, Mario Zoratti, Karin Nowikovsky   +8 more
doaj   +1 more source

Acute oral sodium propionate supplementation raises resting energy expenditure and lipid oxidation in fasted humans [PDF]

, 2018
Short chain fatty acids (SCFAs), produced from fermentation of dietary fibre by the gut microbiota, have been suggested to modulate energy metabolism. Previous work using rodent models have demonstrated that oral supplementation of the SCFA propionate ...
Baldwin, Besten, Boets, Canfora, Canfora, Chambers, Chandramouli, De Vadder, Flint, Frayn, Ge, Kimura, Kimura, Kummitha, Ludwig, Morrison, Peters, Psichas, Ridaura, Weir   +19 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Empowering Young Adults as Agents of Household Dietary Change: Findings From a Pilot Study Involving a Digital, Family-Led Sodium Reduction Intervention in Singapore

Current Developments in Nutrition
Background: Unhealthy dietary habits such as high-sodium intake, are socially embedded and often resistant to individual-level interventions. Family-led approaches, where 1 member initiates change within the household, may offer a more effective ...
Kimberly Mei Yi Low, Cindy Mei Jun Chan, Ian Yi Han Ang, Mary Foong-Fong Chong, Shahmir H Ali   +4 more
doaj   +1 more source