Results 271 to 280 of about 102,180 (356)

Engineered Multifunctional Hydrogel Delivering Novel CBX7 Inhibitor Modulates Cuproptosis Via Liquid–Liquid Phase Separation to Restore Cardiac Function in Aged Myocardial Infarction

open access: yesAdvanced Science, EarlyView.
An age‐adapted therapy pairs δ‐Amyrenone, a CBX7 inhibitor, with an alginate hydrogel (CSAδ) to rescue infarcted elderly hearts. CSAδ disrupts CBX7–ATP7A liquid–liquid phase separation, restores ATP7A trafficking and copper efflux, suppresses cuproptosis, supplies oxygen, scavenges ROS, promotes M2 polarization, supports angiogenesis, and enhances ...
Jun Liu   +11 more
wiley   +1 more source

Bioengineered Skin Grafts from Patient‐Derived Decellularized Extracellular Matrix and Autologous Cells for Personalized Regenerative

open access: yesAdvanced Science, EarlyView.
This study presents a patient‐specific skin model using autologous cells, decellularized dermal ECM, and keratin–alginate bioinks. The model supports cell compatibility, collagen deposition, and epidermal differentiation within a biomimetic ECM environment.
RaeHui Kang   +10 more
wiley   +1 more source

Li/Al‐LDH Reinforced Polyacrylamide/Xanthan Gum Semi‐Interpenetrating Network Nano‐Conductive Hydrogels for Stress Sensing and Wearable Device Applications

open access: yesAdvanced Science, EarlyView.
PXL hydrogel is prepared by in situ polymerization of acrylamide (AM) between Li/Al‐LDH nanosheets and forming a semi‐interpenetrating network structure with xanthan gum (XG). The in situ polymerization of AM ensures the uniform distribution of Li/Al‐LDH within the hydrogel network.
Zhiwei Hu   +16 more
wiley   +1 more source

Nanoparticle‐Functionalized Cellulose Through Biosynthesis‐Only Approach

open access: yesAdvanced Science, EarlyView.
This study reports the first covalent incorporation of glucose‐modified carbon dots (Glu‐CDs) into bacterial cellulose (BC) via microbial fermentation, resulting in BC nanofibers that exhibit uniform cyan fluorescence. A 3D‐printable hydrogel (Glu‐CDs‐BC‐SA) is developed, facilitating the fabrication of fluorescent structures. This work demonstrates an
Chunyu Ji   +4 more
wiley   +1 more source

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