Results 61 to 70 of about 11,691 (203)
پزشکی بالینی ابن سینا, 2016 Introduction & Objective: Sodium arsenite disturbs the differentiation of adult rat bone marrow mesenchymal stem cells (rMSCs) to Osteoblast through oxidative stress.
Malek Soleimani Mehranjani +3 more
doaj
The Role of N6‐Methyladenosine Modification in Health and Disease
MedComm, Volume 7, Issue 6, June 2026.N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li +6 more
wiley +1 more source
, 2013 Chronic arsenic toxicity is a global health problem that affects more than 100 million people worldwide. Long-term health effects of inorganic sodium arsenite in drinking water may result in skin, lung and liver cancers and in severe neurological ...
Ivanov, Vladimir N., Hei, Tom K.
core +1 more source
ACR3 as a Key Regulator Antimicrobial Lipopeptide Synthesis and Efflux in Bacillus velezensis HN‐1
Molecular Plant Pathology, Volume 27, Issue 6, June 2026.Lipopeptides are natural antibiotics produced by Bacillus velezensis. Mutation of acr3 led to the complete loss of antimicrobial activity. Following the biological assays for validation, we found ACR3 protein may serve as a master switch of lipopeptides synthesis regulation, and control transmembrane transport of lipopeptides by the ABC pathway ...
Yuying Shen +10 more
wiley +1 more source
Probing the Biological Plausibility of Fluoride as an Endocrine Disruptor
Birth Defects Research, Volume 118, Issue 5, May 2026.ABSTRACT Background Fluoride has come under recent scrutiny regarding concerns over potential neurodevelopmental and endocrine‐related toxicities, with recent reviews by the National Toxicology Program (NTP) and European Food Safety Authority (EFSA) concluding with moderate or reasonable confidence, respectively, that exposure to drinking water having ...
Ashley M. Mudd +2 more
wiley +1 more source
Glia, Volume 74, Issue 5, May 2026.ZSWIM8, an E3 ubiquitin ligase that broadly targets IDR‐rich proteins, drives MiR‐7‐dependent AGO2 degradation and the turnover of many RBPs. Loss of ZSWIM8 leads to MiR‐7 accumulation in oligodendrocyte progenitor cells and myelination defects in the developing brain. ABSTRACT Proteostasis of proteins with intrinsically disordered regions (IDRs) is of
Jing Lei +13 more
wiley +1 more source
Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1
Advanced Science, Volume 13, Issue 20, 9 April 2026.Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang +10 more
wiley +1 more source
Advanced Science, Volume 13, Issue 23, 23 April 2026.Astrocytic TIA1‐mediated stress granules (SGs) promote demyelination by sequestering the mRNA of cholesterol synthesis genes. In this model, astrocytic TIA1‐mediated SGs were increased in the optic nerves of EAE mice, leading to the downregulation of cholesterol synthesis genes such as HMGCS1 through sequestration of their mRNA into SGs, which ...
Zheyu Fang +11 more
wiley +1 more source
Toxicology Reports, 2016 The impact of sublethal toxicity of sodium arsenite on hematological and certain biochemical parameters of the fresh water catfish Clarias batrachus has been analyzed following exposure of sublethal concentration (1 mg/L; 5% of LC50 value) of sodium ...
Randhir Kumar, T.K. Banerjee
doaj +1 more source
The minimum inhibitory concentration (MIC) of E. coli isolates against sodium arsenite [(As(III)].
, 2022 The minimum inhibitory concentration (MIC) of E. coli isolates against sodium arsenite [(As(III)].
Brandon M. Flatgard (14237309) +12 more
core +1 more source