Results 41 to 50 of about 11,691 (203)

Carvacrol ameliorates sodium arsenite-induced intestinal toxicity

open access: yesTürk Doğa ve Fen Dergisi, 2023
Arsenic is a very dangerous metal that is widely distributed in the environment as a result of anthropogenic and natural processes. On the other hand, it is thought that treatment with natural flavonoids may protect against arsenic toxicity. Carvacrol (CRV) is a naturally occurring phenolic compound with anti-inflammatory, anti-apoptotic, and ...
Mustafa İLERİTÜRK, Özge KANDEMİR
openaire   +3 more sources

Modulation of the Stress Granule Component Carhsp1 Mitigates Disease‐Associated Deficits in Spinocerebellar Ataxia Type 3 Mouse Models

open access: yesMovement Disorders, EarlyView.
Abstract Background Spinocerebellar ataxia type 3 (SCA3) is a polyglutamine (polyQ) neurogenerative disorder that results from CAG trinucleotide repeat expansions in the ATXN3 gene, leading to toxic protein aggregate formation and cellular pathway dysfunction.
Tiago Moreira‐Gomes   +9 more
wiley   +1 more source

Exploring Interactive Effects of Arsenic and Selenium Exposure on Larval Zebrafish (Danio rerio)

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Arsenic contamination in aquatic ecosystems is a major environmental concern. Selenium (Se) helps mitigate oxidative stress and hence could reduce the toxic effects of arsenic. However, Se can also be toxic at high concentrations. Given that these metalloids commonly co‐occur in the environment, there is a pressing need for further research ...
Owen Luo   +6 more
wiley   +1 more source

Quercetin and catechin supplementation provide protection against arsenic and mancozeb-induced toxicity in Wistar rats

open access: yesFood Chemistry Advances, 2023
The study was designed to determine the ameliorative potential of quercetin and catechin against the toxicity induced by co-exposure to Mancozeb (MZ) and arsenic in Wistar rats.
Rasia Yousuf   +4 more
doaj   +1 more source

Synergistic Toxicity of Low‐Concentration Metal Mixture on Male Rats: Reproductive, Renal, and Hepatic Effects

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Mining plays a crucial role in economic development, but improper management can lead to severe environmental degradation. Particularly for iron ore, mining generates vast amounts of tailings often stored in unstable dams. This study aims to investigate the toxicological impacts of environmentally relevant concentrations of metals mixture ...
Kalinka Helóra Gomes de Almeida   +7 more
wiley   +1 more source

Effect of CuII(atsm) on SGs in HeLa cells induced by sodium arsenite.

open access: yes, 2012
Cells were treated for 1 hr with 500 µM sodium arsenite in the presence or absence of 1 µM CuII(atsm) (1 hr) and TDP-43 and HuR were examined by immunofluoresence. A–C: untreated, D–F: sodium arsenite treated, G–I: sodium arsenite and CuII(atsm). Green  =
Jeffrey R. Liddell (144937)   +11 more
core   +1 more source

Two‐Nanosensor Electrochemical Profiling of Catecholamine Vesicle Interactions With Acute and Chronic Stress Granules in Living Cells

open access: yesAngewandte Chemie, Volume 138, Issue 15, 6 April 2026.
A two‐nanosensor electrochemical strategy quantitatively distinguishes reactive oxygen species (ROS) in stress granules (SGs) from catecholamines in vesicles inside living cells. Chronic SGs formed under prolonged stress show elevated ROS and slower release, consistent with SG aging, and promote neurotransmitter loading likely through vesicle fusion ...
Hui Gu   +3 more
wiley   +2 more sources

Role of human RNase 7 in neuronal and glial cell models: moving towards an unexpected new functional link

open access: yesThe FEBS Journal, EarlyView.
Human RNase 7 is known to exert antimicrobial activity in epithelial tissues. Here, using SH‐SY5Y and U‐87 MG, neuroblastoma and glioblastoma cell lines, respectively, we found that RNase 7 enhances immune responses to LPS stimulation by reducing the expression of pro‐inflammatory cytokines, nitric oxide, and ROS.
Rosanna Culurciello   +9 more
wiley   +1 more source

Removal of Arsenite and Arsenate by Indigenous Iron Ores of Pakistan

open access: yesPakistan Journal of Analytical & Environmental Chemistry, 2020
This study is focusing on the comparative study of arsenite and arsenate adsorption from the water via indigenous iron ores. The Sindh and Punjab provinces of Pakistan are badly affected by Arsenic (As) toxicity as the people are consuming arsenic ...
Zulfiqar Ali Bhatti   +3 more
doaj   +1 more source

Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism

open access: yesThe FEBS Journal, EarlyView.
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney   +10 more
wiley   +1 more source

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