Results 21 to 30 of about 11,691 (203)

Low Dose and Long Term Toxicity of Sodium Arsenite Caused Caspase Dependent Apoptosis Based on Morphology and Biochemical Character [PDF]

open access: yesCell Journal, 2012
Objective: Although arsenite is toxic it is currently recommended for the treatment of malignancies. In this study the effects of sub-micromolar concentrations of sodium arsenite on the viability, morphology and mechanism of cell death of rat bone marrow
Mohammad Hussein Abnosi   +1 more
doaj   +1 more source

Effects of Curcumin on Sodium Arsenite Induced Neoplastic Cell Transformation in Balb/c 3T3 Cells [PDF]

open access: yesBrazilian Archives of Biology and Technology, 2021
HIGHLIGHTS Sodium arsenite can cause neoplastic transformation in cells. Curcumin reduced cell viability and increased LDH activity in transformed Balb/c 3T3 cells. Curcumin caused DNA damage in transformed Balb/c 3T3 cells.
Busra Demircioglu   +4 more
doaj   +1 more source

Protective effects of hexane fraction of Costus afer leaves against sodium arsenite-induced hepatotoxicity and nephrotoxicity in male albino wistar rats [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2020
Arsenite is a toxic metallic pollutant known to cause hepatotoxic and nephrotoxic injuries. Costus afer Ker Gawl. is an indigenous medicinal plant used as therapy for numerous tissue disorders. Thus, this study investigated the protective potential of C.
G. N. Anyasor   +2 more
doaj   +1 more source

Effect of Sodium Arsenite on Mouse Skin Carcinogenesis [PDF]

open access: yesToxicologic Pathology, 2015
Arsenic is carcinogenic in human beings, and environmental exposure to arsenic is a public health issue that affects large populations worldwide. Thus, studies are needed to determine the mode of action of arsenic and prevent harmful effects arising from arsenic intake.
Mónica A, Palmieri, Beatriz L, Molinari
openaire   +2 more sources

Arsenic compounds activate MAPK and inhibit Akt pathways to induce apoptosis in MA‐10 mouse Leydig tumor cells

open access: yesCancer Medicine, 2023
Arsenic compounds have been applied treating acute promyelocytic 1eukemia and solid tumors with brief mechanism investigations. In fact, we have demonstrated that sodium arsenite plus dimethylarsenic acid could activate apoptosis in MA‐10 mouse Leydig ...
Wei‐Sheng Juan   +6 more
doaj   +1 more source

Protective Effects of Phyllanthus Emblica Leaf Extract on Sodium Arsenite-mediated Adverse Effects in Mice [PDF]

open access: yes, 2015
2015-02Groundwater contamination of arsenic is the major cause of a serious health hazard in Bangladesh. No specific treatment is yet available to manage the large number of individuals exposed to arsenic.
SAYED, SADIA   +5 more
core   +1 more source

Effect of Phyllanthus amarus in sodium arsenite-induced tissue damage

open access: yesBangladesh Journal of Pharmacology, 2022
This study aims to evaluate the effect of alcoholic extract of Phyllanthus amarus leaves on arsenic-induced histological changes in Wistar rats. Rats were divided into 4 groups: Group I: normal control; Group II: rats received sodium arsenite (40 mg/kg);
Hashim Achummantakath   +2 more
doaj   +1 more source

Kinetic and Adsorption Study for Removal of Arsenic from Aqueous Medium by Low Cost Bentonite of Rajmahal Hills and Hazaribagh, Jharkhand [PDF]

open access: yesNature Environment and Pollution Technology, 2020
The paper deals with the feasibility of arsenite removal by the adsorption from bentonite mineral. Groundwater arsenic contamination has been reported in different parts of the world including Jharkhand, Bihar and Uttar Pradesh.
Sourav Majumder and Ashok Kr. Jha
doaj   +1 more source

MiR-96-5p Suppresses Progression of Arsenite-Induced Human Keratinocyte Proliferation and Malignant Transformation by Targeting Denticleless E3 Ubiquitin Protein Ligase Homolog

open access: yesToxics, 2023
Long-term exposure to arsenic has been linked to a variety of cancers, among which skin cancer is the most prevalent form. However, the mechanism underlying arsenic carcinogenesis is unclear, and there is still limited information on the role of miRNAs ...
Yan Li   +6 more
doaj   +1 more source

The Effects of Vitamin C on the Quality of Semen, Testicular Tissue, and Apoptosis in Mice Exposed to Sodium Arsenite

open access: yesPharmaceutical and Biomedical Research, 2022
Background: Arsenic is a heavy metal that causes malformation. It affects the reproductive system of men by induction of oxidative stress.  Objectives: This study investigated the effect of Vitamin C (Vit C), as a potent antioxidant, on sperm quality and
Ebrahim Cheraghi   +2 more
doaj  

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