Results 1 to 10 of about 1,170,402 (290)

Sodium Butyrate Attenuates AGEs-Induced Oxidative Stress and Inflammation by Inhibiting Autophagy and Affecting Cellular Metabolism in THP-1 Cells

Molecules, 2022
In recent years, sodium butyrate has gained increased attention for its numerous beneficial properties. However, whether sodium butyrate could alleviate inflammatory damage by macrophage activation and its underlying mechanism remains unclear.
Man Yan, Xiang Li, Chang Sun, Jiajun Tan, Yuanyuan Liu, Mengqi Li, Zishang Qi, Jiayuan He, Dongxu Wang, Liang Wu   +9 more
doaj   +2 more sources

Prebiotic Inulin and Sodium Butyrate Attenuate Obesity-Induced Intestinal Barrier Dysfunction by Induction of Antimicrobial Peptides

Frontiers in Immunology, 2021
Defects in the mucosal barrier have been associated with metabolic diseases such as obesity and non-alcoholic fatty liver disease (NAFLD). Mice fed a Western-style diet (WSD) develop obesity and are characterized by a diet-induced intestinal barrier ...
Julia Beisner, Louisa Filipe Rosa, Valentina Kaden-Volynets, Iris Stolzer, Claudia Günther, Stephan C. Bischoff   +5 more
doaj   +2 more sources

Sodium acetate/sodium butyrate alleviates lipopolysaccharide-induced diarrhea in mice via regulating the gut microbiota, inflammatory cytokines, antioxidant levels, and NLRP3/Caspase-1 signaling

Frontiers in Microbiology, 2022
Diarrhea is a word-widely severe disease coupled with gastrointestinal dysfunction, especially in cattle causing huge economic losses. However, the effects of currently implemented measures are still not enough to prevent diarrhea.
Xiushuang Chen, Xiushuang Chen, Qinghui Kong, Xiaoxiao Zhao, Xiaoxiao Zhao, Chenxi Zhao, Chenxi Zhao, Pin Hao, Pin Hao, Irfan Irshad, Hongjun Lei, Hongjun Lei, Muhammad Fakhar-e-Alam Kulyar, Muhammad Fakhar-e-Alam Kulyar, Zeeshan Ahmad Bhutta, Hassan Ashfaq, Qiang Sha, Kun Li, Kun Li, Yi Wu, Yi Wu   +20 more
doaj   +2 more sources

Combining Sodium Butyrate With Cisplatin Increases the Apoptosis of Gastric Cancer In Vivo and In Vitro via the Mitochondrial Apoptosis Pathway

Frontiers in Pharmacology, 2021
Introduction: The gastrointestinal malignancy, gastric cancer (GC), has a high incidence worldwide. Cisplatin is a traditional chemotherapeutic drug that is generally applied to treat cancer; however, drug tolerance affects its efficacy.
Yangbo Li, Yangbo Li, Yangbo Li, Pengzhan He, Pengzhan He, Pengzhan He, Yinghui Liu, Yinghui Liu, Yinghui Liu, Mingming Qi, Mingming Qi, Mingming Qi, Weiguo Dong, Weiguo Dong, Weiguo Dong   +14 more
doaj   +2 more sources

Functional Comparison of Clostridium butyricum and Sodium Butyrate Supplementation on Growth, Intestinal Health, and the Anti-inflammatory Response of Broilers

Frontiers in Microbiology, 2022
Butyrate has been reported to promote proliferation of colonic epithelial cells and maintain intestinal barrier integrity in broilers. Although supplementation of Clostridium butyricum and sodium butyrate have been shown to confer benefits on broilers ...
Ling Liu, Huayun Ling, Huayun Ling, Wei Zhang, Ying Zhou, Youguo Li, Nan Peng, Shumiao Zhao   +7 more
doaj   +2 more sources

Sodium Butyrate Alleviates Mouse Colitis by Regulating Gut Microbiota Dysbiosis

Animals, 2020
Inflammatory bowel disease (IBD) develops as a result of complicated interactions between genetic susceptibility, excessive innate immunity, and environmental factors, which are mainly related to the gut microbiota.
Xiujing Dou, Nan Gao, Di Yan, Anshan Shan   +3 more
doaj   +2 more sources

The Impact of Microbiome and Microbiota-Derived Sodium Butyrate on Drosophila Transcriptome and Metabolome Revealed by Multi-Omics Analysis

Metabolites, 2021
The host microbiome plays an important role in regulating physiology through microbiota-derived metabolites during host-microbiome interactions. However, molecular mechanism underly host-microbiome interactions remains to be explored.
Fan Zhou, Biaodi Liu, Xin Liu, Yan Li, Luoluo Wang, Jia Huang, Guanzheng Luo, Xiaoyun Wang   +7 more
doaj   +2 more sources

Impact of Sodium Butyrate Treatment in LPS-Stimulated Peripheral Blood Mononuclear Cells of Poorly Controlled Type 2 DM

Frontiers in Endocrinology, 2021
Type 2 diabetes mellitus (T2DM) is associated with chronic low-grade inflammation, which is marked by the dysregulation of innate and adaptive immune responses. Therefore, reducing inflammation, possibly through an immunoregulatory agent, may play a role
Heri Wibowo, Dante S. Harbuwono, Dicky L. Tahapary, Rona Kartika, Saraswati Pradipta, Rahma A. Larasati   +5 more
doaj   +2 more sources

Transcriptomic Insights into the Protective Effects of Apigenin and Sodium Butyrate on Jejunal Oxidative Stress in Ducks. [PDF]

Vet Sci
Apigenin and sodium butyrate have been reported to help alleviate oxidative stress. This study evaluated the jejunal transcriptomic responses in ducks receiving apigenin and sodium butyrate supplementation under oxidative stress.
Zhou N, Sun H, Tian Y, Zhang H, Xian X, Yu H, Zhao L, Chen Y, Sun M, Zhang Y, Meng T, Lu L.   +11 more
europepmc   +2 more sources

Clinical Efficacy of Sodium Butyrate in Managing Pediatric Inflammatory Bowel Disease. [PDF]

Life (Basel)
Background: Few studies have evaluated the efficacy of butyric acid in treating children with inflammatory bowel disease (IBD). In children and adolescents with recently diagnosed IBD, the purpose of this research was to assess the efficacy of oral ...
Goldiș A, Dragomir R, Mercioni MA, Sirca D, Goldiș C, Enatescu I, Olariu L, Belei O.   +7 more
europepmc   +2 more sources