Results 221 to 230 of about 1,170,402 (290)

The Impact of the Histone Deacetylase Inhibitor-Sodium Butyrate on Complement-Mediated Synapse Loss in a Rat Model of Neonatal Hypoxia-Ischemia. [PDF]

Mol Neurobiol
Ziabska K, Gewartowska M, Frontczak-Baniewicz M, Sypecka J, Ziemka-Nalecz M.   +4 more
europepmc   +1 more source

Sodium butyrate in Irritable Bowel Syndrome

Journal of Education, Health and Sport
Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder characterized by abdominal pain, bloating, and altered bowel habits. Although its pathophysiology is not fully understood, factors such as gut microbiota imbalance, increased
Aleksandra Kołodziej, Wiktoria Zamirska, Nadia Hornig, Aleksandra Cieplak, Zuzanna Czyżewicz   +4 more
semanticscholar   +3 more sources

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Sodium Butyrate

Definitions, 2020
The sodium salt of butyrate with potential antineoplastic activity. Butyrate, a short chain fatty acid, competitively binds to the zinc sites of class I and II histone deacetylases (HDACs).

semanticscholar   +2 more sources

Sodium butyrate induced keratinocyte apoptosis

Apoptosis, 2006
Apoptosis of keratinocytes is a key mechanism required for epidermal homeostasis and the renewal of damaged cells. Its dysregulation has been implicated in many skin diseases including cancer and hyperproliferative disorders. In the present study, the effect of sodium butyrate, a histone deacetylase inhibitor, on keratinocyte apoptosis was investigated
Daehn, I., Varelias, A., Rayner, T.
openaire   +3 more sources

Sodium Butyrate Downregulates Implant-Induced Inflammation in Mice

Inflammation, 2020
Sodium butyrate (NaBu), a histone deacetylase inhibitor, has shown to exert beneficial actions attenuating inflammation in a number of intestinal and extra-intestinal diseases. However, the effects of NaBu on persistent inflammatory processes as in a response to implantation of foreign material have not been investigated.
Marcela Guimarães Takahashi de Lazari, Luciana Xavier Pereira, Laura Alejandra Ariza Orellano, Karina Scheuermann, Clara Tolentino Machado, Anilton Cesar Vasconcelos, Silvia Passos Andrade, Paula Peixoto Campos   +7 more
openaire   +2 more sources

Sodium butyrate administration modulates the ruminal villus height, inflammation-related gene expression, and plasma hormones concentration in dry cows fed a high-fiber diet.

Animal science journal = Nihon chikusan Gakkaiho, 2022
The objectives of this study were to evaluate the effects of sodium butyrate on the ruminal villus morphology, mRNA expression associated with nutrient metabolism and inflammation in the ruminal epithelium, and plasma concentrations of metabolites and ...
R. Fukumori, Kazuya Doi, Taisei Mochizuki, S. Oikawa, S. Gondaira, T. Iwasaki, K. Izumi   +6 more
semanticscholar   +1 more source

Regulation of Neutrophil Apoptosis by Sodium Butyrate

Biologicals, 1996
Neutrophils have a very short half life because they constitutively undergo apoptosis. Granulocyte-macrophage colony-stimulating factor (GM-CSF) can delay apoptosis, but this agent also primes functions such as the respiratory burst and receptor upregulation.
D, Moulding, J A, Quayle, R E, Stringer, C A, Hart, S W, Edwards   +4 more
openaire   +2 more sources

Sodium butyrate‐induced adhesion in mastocytoma cells

Biology of the Cell, 1984
Sodium butyrate induced adhesion of cultured mastocytoma p‐815 cells to the surface of a standard tissue culture grade petri dish. The ratio of the number of adherent cells to that of total cells (adherent plus floating cells) was dependent on the serum concentration and on the dose of sodium butyrate.
T, Matsuhisa, Y, Mori, H, Tamura
openaire   +2 more sources