Results 231 to 240 of about 1,170,402 (290)

Effect of sodium butyrate on chromatin structure

Biochemical and Biophysical Research Communications, 1980
Abstract Sodium butyrate is able to modify gene expression. It was then interesting to study its effect on chromatin structure. Butyrate modified the accessibility of chromatin from HTC cells to micrococcal nuclease : chromatin was digested to a higher rate until 1.5 % of the DNA was rendered acid soluble, in longer digestion it was attacked to a ...
A, Kitzis, L, Tichonicky, N, Defer, J, Kruh   +3 more
openaire   +2 more sources

Effects of sodium butyrate supplementation on inflammation, gut microbiota, and short‐chain fatty acids in Helicobacter pylori‐infected mice

Helicobacter, 2021
Inflammation induced by Helicobacter pylori (H. pylori) infection is the basis for the pathogenesis of H. pylori. Butyric acid, a diet‐related microbial‐associated metabolite, is connected to inflammation, metabolic syndrome, and other diseases.
Yumei Huang, Yinhuan Ding, Huiyuan Xu, Cheng-guo Shen, xia chen, Changping Li   +5 more
semanticscholar   +1 more source

Plasma pharmacokinetics of butyrate after intravenous administration of sodium butyrate or oral administration of tributyrin or sodium butyrate to mice and rats

Cancer Chemotherapy and Pharmacology, 1999
To define the plasma concentrations of butyrate achieved and the profile of plasma butyrate concentrations versus time in mice and rats treated with tributyrin or sodium butyrate.Female CD2F1 mice were treated with tributyrin by oral gavage or with sodium butyrate by i.v. bolus or oral gavage. Oral tributyrin doses delivered to mice were 3.1, 5.2, 7.8,
M J, Egorin, Z M, Yuan, D L, Sentz, K, Plaisance, J L, Eiseman   +4 more
openaire   +2 more sources

Sodium butyrate alleviates pre‐eclampsia in pregnant rats by improving the gut microbiota and short‐chain fatty acid metabolites production

Journal of Applied Microbiology, 2021
Pre‐eclampsia (PE) affects pregnant patients worldwide, but there is no effective treatment for this condition. We aimed to explore the effect of sodium butyrate (NaB) on PE.
Wenjing Yong, Yanhua Zhao, Xiao'e Jiang, Ping Li   +3 more
semanticscholar   +1 more source

The effect of sodium butyrate on histone modification

Cell, 1978
The hyperacetylation of histones due to treatment of cultured cells with sodium butyrate has been studied. The hyperacetylation is due to inhibition of histone deacetylase. Other short chain fatty acids including acetic, isobutyric and propionic acid also produce increased modification.
L, Sealy, R, Chalkley
openaire   +2 more sources

Preferential alkaline phosphatase isoenzyme induction by sodium butyrate

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1983
SW-620, a continuous cell line derived from a poorly differentiated human colon carcinoma, produces two alkaline phosphatases. Under basal conditions the heat-stable, term-placental is the major isoenzyme and the heat-labile, liver/bone/kidney form represents a minor component.
F, Herz, M, Halwer
openaire   +2 more sources

Sodium Butyrate Stimulates Somatostatin Production by Cultured Cells*

Endocrinology, 1984
Expression of the neuropeptide SRIF can be enhanced by sodium butyrate, a known modulator of gene transcription. Two different cell lines, RIN cells (derived from a rat pancreatic islet tumor) as well as HeLa cells, showed basal secretion of SRIF immunoreactive material that was induced between 5- and 15-fold by sodium butyrate.
R, Green, D, Shields
openaire   +2 more sources

Differentiation of PC12 pheochromocytoma cells by sodium butyrate

Developmental Brain Research, 1987
PC12 pheochromocytoma cells cease dividing and show increased cell-cell and cell-substratum adhesion in response to treatment with sodium butyrate. These changes are accompanied by the rapid appearance of neuron-specific enolase, an APUD cell marker. However, neurofilament proteins, markers for neuronal differentiation, are not induced.
J C, Byrd, H, Alho
openaire   +2 more sources

Sleep induced by sodium butyrate in the cat

Brain Research, 1967
Summary The para-sleep inducing effect of sodium butyrate and related compounds was studied polygraphically in 45 cats with implanted electrodes. The intravenous administration of sodium butyrate (1.5–3mM/kg) induced the para-sleep phase. This phase appeared after a 2–6 min period of induced ortho-sleep, and continued for 3–10 min.
M, Matsuzaki, H, Takagi
openaire   +2 more sources

Induction of cellular transglutaminase biosynthesis by sodium butyrate

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1987
Cellular transglutaminase activity was induced in simian virus-transformed human embryonic lung fibroblasts (WI-38 VA13A) by sodium butyrate. The level of enzyme activity approached a maximum by 6 days; 9-11-fold higher in the presence of sodium butyrate (1 mM) than in its absence.
K N, Lee, P J, Birckbichler, M K, Patterson, E, Conway, M, Maxwell   +4 more
openaire   +2 more sources