Results 241 to 250 of about 1,170,402 (290)
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Sodium butyrate alters erythropoietin glycosylation via multiple mechanisms
Biotechnology and Bioengineering, 2007AbstractRecombinant human erythropoietin (rHuEPO) produced in a human kidney fibrosarcoma cell line, HT1080, was used as a model to study the effects of sodium butyrate (SB) on protein glycosylation. Treatment with 2 mM SB resulted in complex changes with respect to sugar nucleotide pools including an increase in UDP‐Gal and a decrease in UDP‐GlcNac ...
Christopher K, Crowell +5 more
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Benefits of Dietary Butyric Acid, Sodium Butyrate, and Their Protected Forms in Aquafeeds: A Review
, 2020Excessive application of antibiotics to control fish and shrimp diseases in aquaculture has been associated with several drawbacks, such as immune suppression, development of antibiotic-resistant bacterial strains, and elevated levels of antibiotic ...
H. M. Abdel‐Latif +4 more
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The FASEB Journal, 2020
Bladder cancer is one of the most frequently occurring malignant tumors in the urinary system. Sodium butyrate (NaB) is a histone deacetylase inhibitor and exerts remarkable antitumor effects in various cancer cells. MicroRNAs (miRNAs) and autophagy play
Feifan Wang +10 more
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Bladder cancer is one of the most frequently occurring malignant tumors in the urinary system. Sodium butyrate (NaB) is a histone deacetylase inhibitor and exerts remarkable antitumor effects in various cancer cells. MicroRNAs (miRNAs) and autophagy play
Feifan Wang +10 more
semanticscholar +1 more source
Sodium butyrate inhibits histone deacetylation in cultured cells
Cell, 1978Sodium butyrate in millimolar concentrations causes an accumulation of acetylated histone species in a variety of vertebrate cell lines. In all lines tested, butyrate caused hyperacetylation of H3 and H4, and in rat IRC8 cells, H2A and H2B were also affected.
E P, Candido, R, Reeves, J R, Davie
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Pharmacokinetic study of butyric acid administered in vivo as sodium and arginine butyrate salts
Clinica Chimica Acta, 1989Considering that butyrate-treated malignant cells can recover in a transitory fashion a non-cancerous phenotype, the authors carried out a pharmacokinetics study of butyric acid injected as sodium or arginine salts for possible antitumor therapies. In the case of 1-14C-labelled butyrate, the appearance of radioactivity in the blood of injected mice is ...
P, Daniel +7 more
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Sodium butyrate induced structural changes in HeLa cell chromatin
Biochemistry, 1982Postsynthetic modifications of core histones by treatment of HeLa S3 cells with 5mM sodium butyrate lead to alterations in the structure of high molecular weight chromatin. Whole chromatin from butyrate-treated cells, which results in highly acetylated core histones, has an ellipticity [theta]282.5 of 3700 deg cm2 dmol-1 (0.2 mM EDTA, pH 7.4) that is ...
P R, Reczek +3 more
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Sodium butyrate induced alterations in lysosomal enzyme activity
In Vitro Cellular & Developmental Biology, 1985Treatment of cultured HeLa cells with 5 mM sodium butyrate causes an inhibition of growth as well as extensive chemical and morphological differentiation. Lysosomal enzyme activity changes have been associated with both normal and neoplastic growth as well as many aspects of the neoplastic process.
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SODIUM BUTYRATE PREVENTS LETHALITY OF SEVERE SEPSIS IN RATS
Shock, 2007This study was performed to investigate a novel strategy to pharmacologically inhibit high-mobility group box 1 protein (HMGB1) expression with sodium butyrate, a short-chain fatty acid. Using a sepsis model induced by cecal ligation and puncture (CLP), 100 male Wistar rats were randomly divided into 4 groups as follows: control group (10 rats), sham ...
Li-Tian, Zhang +5 more
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Selective Hypermethylation of Transcribed Nucleosomal DNA by Sodium Butyrate
Experimental Cell Research, 1994Previous studies have shown that treatment of cultured fibroblasts with millimolar concentrations of sodium butyrate results in increased methylation of cytosine residues in DNA. In this study, active nucleosomes were fractionated from the inactive ones by organomercurial agarose column chromatography.
L C, Boffa, M R, Mariani, M I, Parker
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Sodium butyrate stimulates polyamine biosynthesis in colon cancer cells
Surgical Oncology, 1992Differentiation inducers act through polyamine-dependent and independent pathways. Sodium butyrate (NaB) inhibits proliferation and induces terminal differentiation in human and murine cancer cell lines. An effect of this agent on polyamine biosynthesis has not been demonstrated previously.
D, Parekh +4 more
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