Results 21 to 30 of about 1,170,402 (290)

Encapsulation of butyrate using low-alkali konjac gel induced by ethanol for colonic delivery

Food Hydrocolloids for Health, 2021
Butyrate administrated in proper concentration is beneficial to the human colon environment. However, the delivery of butyrate to the colon is quite difficult as butyrate could be easily absorbed in the upper gastrointestinal tract.
Yousong Ma, Sijia Peng, Ning Tang, Yongqiang Cheng   +3 more
doaj   +1 more source

Sodium butyrate ameliorates diabetic retinopathy in mice via the regulation of gut microbiota and related short-chain fatty acids

Journal of Translational Medicine, 2023
Background Diabetic retinopathy (DR) development is associated with disturbances in the gut microbiota and related metabolites. Butyric acid is one of the short-chain fatty acids (SCFAs), which has been found to possess a potential antidiabetic effect ...
Yinhua Huang, Zhijie Wang, Bo Ye, J. Ma, Shangli Ji, Wang Sheng, Suna Ye, Yiwen Ou, Yanfang Peng, Xu Yang, Jiansu Chen, Shibo Tang   +11 more
semanticscholar   +1 more source

Neuroprotective Effects of Sodium Butyrate by Restoring Gut Microbiota and Inhibiting TLR4 Signaling in Mice with MPTP-Induced Parkinson’s Disease

Nutrients, 2023
Parkinson’s disease (PD) is a prevalent type of neurodegenerative disease. There is mounting evidence that the gut microbiota is involved in the pathogenesis of PD.
T. Guo, Zheng Zhang, Y. Sun, Rui-Yang Zhu, Fei Wang, Lian-Ju Ma, Lin Jiang, Handeng Liu   +7 more
semanticscholar   +1 more source

Sodium butyrate induces ferroptosis in endometrial cancer cells via the RBM3/SLC7A11 axis

Apoptosis, 2023
Ferroptosis is a form of programmed cell death with important biological functions in the progression of various diseases, and targeting ferroptosis is a new tumor treatment strategy. Studies have shown that sodium butyrate plays a tumor-suppressing role
Ziwei Wang, Wan Shu, Rong-wei Zhao, Y. Liu, Hongbo Wang   +4 more
semanticscholar   +1 more source

Sodium Butyrate Ameliorates Oxidative Stress-Induced Intestinal Epithelium Barrier Injury and Mitochondrial Damage through AMPK-Mitophagy Pathway

Oxidative Medicine and Cellular Longevity, 2022
Sodium butyrate has gained increasing attention for its vast beneficial effects. However, whether sodium butyrate could alleviate oxidative stress‐induced intestinal dysfunction and mitochondrial damage of piglets and its underlying mechanism remains ...
Xin Li, Chunchun Wang, Jiang Zhu, Qian Lin, Minjie Yu, J.S. Wen, Jie Feng, Caihong Hu   +7 more
semanticscholar   +1 more source

Impacts of sodium butyrate on intestinal mucosal barrier and intestinal microbial community in a weaned piglet model

Frontiers in Microbiology, 2023
Objective Butyrate is thought to enhance intestinal mucosal homeostasis, but the detailed mechanism remains unclear. Therefore, further investigation on the mechanism of butyrate regulation of intestinal mucosal homeostasis was performed.
Han Liu, Jing Zhao, Wenju Zhang, C. Nie
semanticscholar   +1 more source

Modulation of GABA by sodium butyrate ameliorates hypothalamic inflammation in experimental model of PCOS

BMC Neuroscience, 2023
Polycystic ovarian syndrome (PCOS) is a known endocrine disorder that has affected many women of childbearing age, and is accompanied by various neurodegenerative conditions. Hence, this study investigates the impact of butyrate in reversing hypothalamic-
Oony-Iye Eepho, Al-Amin M. Bashir, Adesola A. Oniyide, Ayodeji Aturamu, O. V. Owolabi, Isaac O. Ajadi, A. Fafure, M. Ajadi, Stephanie E. Areloegbe, K. Olaniyi   +9 more
semanticscholar   +1 more source

Sodium butyrate reduces ammonia emissions through glutamate metabolic pathways in cecal microorganisms of laying hens

Ecotoxicology and Environmental Safety, 2022
Ammonia emission is an important problem that needs to be solved in laying hen industries. Sodium butyrate (SB) is considered to have potential for reducing ammonia production because of its ability to improve nitrogen metabolism.
Zhikang Zhong, Chao Wang, Huaidan Zhang, Jiandui Mi, Juan Boo Liang, Xindi Liao, Yinbao Wu, Yan Wang   +7 more
doaj   +1 more source

Sodium butyrate in both prevention and supportive treatment of colorectal cancer

Frontiers in Cellular and Infection Microbiology, 2022
Accumulating evidence suggests that selected microbiota-derived metabolites play a significant role in both tumor prevention and supportive treatment of cancer.
Karolina Kaźmierczak-Siedlecka, L. Marano, E. Merola, F. Roviello, K. Polom   +4 more
semanticscholar   +1 more source

Sodium Butyrate Effectiveness in Children and Adolescents with Newly Diagnosed Inflammatory Bowel Diseases—Randomized Placebo-Controlled Multicenter Trial

Nutrients, 2022
Background: Butyric acid’s effectiveness has not yet been assessed in the pediatric inflammatory bowel disease (IBD) population. This study aimed to evaluate the effectiveness of oral sodium butyrate as an add-on to standard therapy in children and ...
A. Pietrzak, M. Banasiuk, M. Szczepanik, A. Borys-Iwanicka, T. Pytrus, J. Walkowiak, A. Banaszkiewicz   +6 more
semanticscholar   +1 more source