Results 31 to 40 of about 41,550 (274)

Sodium butyrate attenuates peritoneal fibroproliferative process in mice

open access: yesExperimental Physiology, 2022
AbstractThe aim of this study was to identify the bio‐efficacy of sodium butyrate (NaBu) on preventing the development of peritoneal fibrovascular tissue induced by implantation of a synthetic matrix in the abdominal cavity.Polyether–polyurethane sponge discs were implanted in the peritoneal cavity of mice, which were treated daily with oral ...
Marcela Guimarães Takahashi De Lazari   +6 more
openaire   +4 more sources

Synergistic effect of sodium butyrate and oxaliplatin on colorectal cancer

open access: yesTranslational Oncology, 2023
Oxaliplatin (OXA) is a chemotherapy agent commonly used in the treatment of colorectal cancer (CRC). Sodium butyrate (NaB) has an antitumor effect.In total, 30 patients in stage III who completed 8 cycles of chemotherapy regimens were recruited for this study. The patients were divided into good and bad groups based on the chemotherapy efficacy.
Han Shuwen   +5 more
openaire   +3 more sources

Sodium butyrate prevents radiation-induced cognitive impairment by restoring pCREB/BDNF expression

open access: yesNeural Regeneration Research, 2019
Sodium butyrate is a histone deacetylase inhibitor that affects various types of brain damages. To investigate the effects of sodium butyrate on hippocampal dysfunction that occurs after whole-brain irradiation in animal models and the effect of sodium ...
Hae June Lee   +8 more
doaj   +1 more source

Sodium butyrate reduces ammonia emissions through glutamate metabolic pathways in cecal microorganisms of laying hens

open access: yesEcotoxicology and Environmental Safety, 2022
Ammonia emission is an important problem that needs to be solved in laying hen industries. Sodium butyrate (SB) is considered to have potential for reducing ammonia production because of its ability to improve nitrogen metabolism.
Zhikang Zhong   +7 more
doaj  

An antioxidant ameliorates allergic airway inflammation by inhibiting HDAC 1 via HIF-1α/VEGF axis suppression in mice

open access: yesScientific Reports, 2023
Histone deacetylase inhibitors (HDACi) are novel class of drugs as they are involved in post translational modification of several proteins involved in signaling pathways related to asthma.
Ramiya Islam, D. Dash, Rashmi Singh
doaj   +1 more source

Sodium butyrate protects against severe burn-induced remote acute lung injury in rats. [PDF]

open access: yesPLoS ONE, 2013
High-mobility group box 1 protein (HMGB1), a ubiquitous nuclear protein, drives proinflammatory responses when released extracellularly. It plays a key role as a distal mediator in the development of acute lung injury (ALI). Sodium butyrate, an inhibitor
Xun Liang   +8 more
doaj   +1 more source

Sodium Butyrate More Effectively Mitigates the Negative Effects of High-Concentrate Diet in Dairy Cows than Sodium β-Hydroxybutyrate via Reducing Free Bacterial Cell Wall Components in Rumen Fluid and Plasma

open access: yesToxins, 2021
The present study was aimed at investigating the effects of sodium butyrate and sodium β-hydroxybutyrate on lactation and health of dairy cows fed a high-concentrate (HC) diet. Eighty mid-lactation dairy cows with an average milk yield of 33.75 ± 5.22 kg/
Yongjiang Wu   +8 more
doaj   +1 more source

Effects of sodium butyrate on methamphetamine-sensitized locomotor activity [PDF]

open access: yesBehavioural Brain Research, 2013
Neuroadaptations associated with behavioral sensitization induced by repeated exposure to methamphetamine (MA) appear to be involved in compulsive drug pursuit and use. Increased histone acetylation, an epigenetic effect resulting in altered gene expression, may promote sensitized responses to psychostimulants.
Robert Hitzemann   +6 more
openaire   +3 more sources

Sodium butyrate reduces ammonia production in the cecum of laying hens by regulating ammonia-producing bacteria

open access: yesPoultry Science, 2023
: Sodium butyrate is a commonly used feed additive and can reduce ammonia (NH3) emissions from laying hens, but the mechanism of this effect is unknown.
Shuo Liu   +5 more
doaj  

Natural Design of a Stabilized Cross‐β Fold: Structure of the FuA FapC from Pseudomonas Sp. UK4 Reveals a Critical Role for Stacking of Imperfect Repeats

open access: yesAdvanced Materials, EarlyView.
We report a 3.2 Å cryoEM structure of functional amyloid protein FapC from Pseudomonas sp. UK4, an essential component of bacterial biofilm, which reveals a Greek key‐shaped protofilament, supports bioinformatically determined motifs, nuances AlphaFold predictions, emphasizes heterogeneous cross‐β stacking in amyloid cross‐seeding and shows strain ...
Yanting Jiang   +13 more
wiley   +1 more source

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