Results 41 to 50 of about 1,170,402 (290)

Sodium butyrate attenuates peritoneal fibroproliferative process in mice

open access: yesExperimental Physiology, 2022
AbstractThe aim of this study was to identify the bio‐efficacy of sodium butyrate (NaBu) on preventing the development of peritoneal fibrovascular tissue induced by implantation of a synthetic matrix in the abdominal cavity.Polyether–polyurethane sponge discs were implanted in the peritoneal cavity of mice, which were treated daily with oral ...
Marcela Guimarães Takahashi De Lazari   +6 more
openaire   +4 more sources

The effectiveness of microencapsulated sodium butyrate at reducing symptoms in patients with irritable bowel syndrome

open access: yesGastroenterology Review, 2022
Aim The aim of the study was to assess the effectiveness of a patented preparation of sodium butyrate in the triglyceride matrix at reducing clinical symptoms and improving quality of life in patients with irritable bowel syndrome (IBS).
K. Lewandowski   +4 more
semanticscholar   +1 more source

A molecular basis for selective antagonist destabilization of dopamine D3 receptor quaternary organization [PDF]

open access: yes, 2017
The dopamine D3 receptor (D3R) is a molecular target for both first-generation and several recently-developed antipsychotic agents. Following stable expression of this mEGFP-tagged receptor, Spatial Intensity Distribution Analysis indicated that a ...
Caltabiano, Gianluigi   +6 more
core   +2 more sources

Effect of Sodium Butyrate on p16INK4a, p14ARF, p15INK4b, Class I HDACs (HDACs 1, 2, 3) Class II HDACs (HDACs 4, 5, 6), Cell Growth Inhibition and Apoptosis Induction in Pancreatic Cancer AsPC-1 and Colon Cancer HCT-116 Cell Lines

open access: yesAsian Pacific Journal of Cancer Prevention, 2022
Background: In higher eukaryotes, cell-cycle transitions are regulated by different cyclin-dependent kinases (Cdks) and Cdk inhibitors (CKIs). CKIs include two groups, the Ink4 (p16INK4a, p15INK4b, p18INK4c, and p19INK4d) and the Cip/Kip (p21Cip1 ...
M. Sanaei, F. Kavoosi
semanticscholar   +1 more source

Mast cell clones: a model for the analysis of cellular maturation. [PDF]

open access: yes, 1982
Cloned mouse mast cells resemble, by ultrastructure, immature mast cells observed in vivo. These mast cell clones can be grown in the absence of any other cells, facilitating direct investigations of their biochemistry and function.
Cantor, H   +10 more
core   +2 more sources

Enhancing methane production from food waste fermentate using biochar. The added value of electrochemical testing in pre-selecting the most effective type of biochar [PDF]

open access: yes, 2017
Background: Recent studies have suggested that addition of electrically conductive biochar particles is an effective strategy to improve the methanogenic conversion of waste organic substrates, by promoting syntrophic associations between acetogenic and ...
Cruz Viggi, Carolina   +11 more
core   +2 more sources

Histone deacetylase inhibitors induce invasion of human melanoma cells in vitro via differential regulation of N-cadherin expression and RhoA activity [PDF]

open access: yes, 2016
Background: Histone deacetylase inhibitors (HDACi) exert multiple cytotoxic actions on cancer cells. Currently, different synthetic HDACi are in clinical use or clinical trials; nevertheless, since both pro-invasive and anti-invasive activities have been
Andrade, Ricardo   +6 more
core   +4 more sources

Treatment of spinal muscular atrophy by sodium butyrate [PDF]

open access: yesProceedings of the National Academy of Sciences, 2001
Spinal muscular atrophy (SMA) is an autosomal recessive disease characterized by degeneration of the anterior horn cells of the spinal cord, leading to muscular paralysis with muscular atrophy. No effective treatment of this disorder is presently available.
J G, Chang   +5 more
openaire   +2 more sources

Sodium Butyrate Alleviates Lipopolysaccharide-Induced Inflammatory Responses by Down-Regulation of NF-κB, NLRP3 Signaling Pathway, and Activating Histone Acetylation in Bovine Macrophages

open access: yesFrontiers in Veterinary Science, 2020
Sodium butyrate is the sodium salt of butyric acid, which possesses many biological functions including immune system regulation, anti-oxidant and anti-inflammatory ability.
Liqiang Jiang   +10 more
doaj   +1 more source

The activation of KSHV lytic cycle blocks autophagy in PEL cells [PDF]

open access: yes, 2015
This study confirms that autophagy is activated concomitantly with KSHV lytic cycle induction, and that autophagy inhibition by BECN1 knockdown reduces viral lytic gene expression.
CIRONE, Mara   +7 more
core   +1 more source

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