Frontiers in Microbiology, 2021 The intestinal microbiome can influence the efficiency and the health status of its host’s digestive system. Indigestible non-starch polysaccharides (NSP) serve as substrates for bacterial fermentation, resulting in short-chain fatty acids like butyrate.
D. Borda-Molina +6 more
semanticscholar +1 more source
Butyrate induces ROS-mediated apoptosis by modulating miR-22/SIRT-1 pathway in hepatic cancer cells
Redox Biology, 2017 Butyrate is one of the short chain fatty acids, produced by the gut microbiota during anaerobic fermentation of dietary fibres. It has been shown that it can inhibit tumor progression via suppressing histone deacetylase and can induce apoptosis in cancer
Kishor Pant +5 more
doaj +1 more source
Comparing the effects of monensin and sodium butyrate on coccidia in post-weaned heifers [PDF]
, 2018 The emergence of antibiotic resistances has raised concerns in society about the widespread use of antibiotics, such as monensin, as growth enhancers in agriculture.
Coffin, Hannah R
core +1 more source
An orally administered butyrate-releasing derivative reduces neutrophil recruitment and inflammation in dextran sulphate sodium-induced murine colitis [PDF]
, 2016 BACKGROUND AND PURPOSE: Butyrate has shown benefits in inflammatory bowel diseases. However, it is not often administered orally because of its rancid smell and unpleasant taste.
BERNI CANANI, ROBERTO +10 more
core +1 more source
Sodium butyrate attenuated neuronal apoptosis via GPR41/Gβγ/PI3K/Akt pathway after MCAO in rats
Journal of Cerebral Blood Flow and Metabolism, 2020 Sodium butyrate, a short-chain fatty acid, is predominantly produced by gut microbiota fermentation of dietary fiber and serves as an important neuromodulator in the central nervous system.
Zhenhua Zhou +7 more
semanticscholar +1 more source
Improving Biomethanation of Chicken Manure by Co-Digestion with Ethanol Plant Effluent [PDF]
, 2019 As the global production of chicken manure has steadily increased, its proper management has become a challenging issue. This study examined process effluent from a bioethanol plant as a co-substrate for efficient anaerobic digestion of chicken manure ...
Bolan +8 more
core +1 more source
Frontiers in Endocrinology, 2018 Type 1 diabetes (T1D) is an autoimmune disease characterized by the immune cell-mediated progressive destruction of pancreatic β-cells. High-mobility group box 1 protein (HMGB1) has been recognized as a potential immune mediator to enhance the ...
Yu Guo +14 more
doaj +1 more source
Cellular Models of Aggregation-Dependent Template-Directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer's Disease [PDF]
, 2015 Copyright © 2015, The American Society for Biochemistry and Molecular Biology. Acknowledgements-We thank Drs Timo Rager and Rolf Hilfiker (Solvias, Switzerland) for polymorph analyses.Peer reviewedPublisher ...
Clunas, Scott +14 more
core +1 more source
Effects of sodium butyrate on methamphetamine-sensitized locomotor activity [PDF]
Behavioural Brain Research, 2013 Neuroadaptations associated with behavioral sensitization induced by repeated exposure to methamphetamine (MA) appear to be involved in compulsive drug pursuit and use. Increased histone acetylation, an epigenetic effect resulting in altered gene expression, may promote sensitized responses to psychostimulants.
John H, Harkness +3 more
openaire +2 more sources
Sodium butyrate alleviates adipocyte inflammation by inhibiting NLRP3 pathway [PDF]
Scientific Reports, 2015 AbstractInsulin resistance (IR) is a common feature of Type II diabetes, metabolic disorders, hypertension and other vascular diseases. Recent studies showed that obesity-induced inflammation may be critical for IR. To investigate the anti-inflammatory effect of sodium butyrate (NaB) on obesity-induced inflammation, the db/db mice were ...
Xukai Wang +5 more
openaire +2 more sources