Results 221 to 230 of about 631,116 (302)

Lidocaine for Sodium Channel Toxicity in Diphenhydramine Overdose: Case Report. [PDF]

Clin Pract Cases Emerg Med
Makki K, Mandil D, Hopson R, Kashin M, Rothenberg R, Reisman N, Farmer B.   +6 more
europepmc   +1 more source

Silicified Wood‐Inspired, High‐Strength Fire‐Resistant Chitin‐Based Aerogels for Sustainable High‐Temperature Thermal Insulation

Advanced Functional Materials, EarlyView.
Inspired by natural silicified wood, a biomimetic mineralized chitin‐derived aerogel is constructed. It can withstand 81 000 times its own weight, and its backside temperature is 130.4°C after exposure to ∼1300°C butane flame for 600 s, exhibiting high‐strength, fire‐resistance, and super thermal‐insulation properties.
Kai Xu, Qihang Lv, Lubin Liu, Zhezhe Zhou, Chentao Yan, Ao Qin, Jianting Ma, Shuhui Liang, Yue Xu, Min Hong, Bin Li, Pingan Song   +11 more
wiley   +1 more source

Solvent Co‐Intercalation Enabled Ca Storage in MoS2 for Ca‐Ion Batteries

Advanced Functional Materials, EarlyView.
Regulating electrolyte solvation levels enables otherwise non‐intercalatable Ca2+ ions to reversibly co‐intercalate into molybdenum disulfide (MoS2) as ether‐solvated species. The intercalation reversibility is strongly governed by solvent chain length, as demonstrated using diethylene glycol dimethyl ether (G2) and tetraethylene glycol dimethyl ether (
Yudong Luo, Matthias Golomb, Yupei Han, Pan He, Neubi Xavier, Wanjun Ren, Yi Lu, Matthew Hopper, Henry R. Tinker, Qiong Cai, Yang Xu   +10 more
wiley   +1 more source

Distinct impacts of sodium channel blockers on the strength-duration properties of human motor cortex neurons. [PDF]

Epilepsia
Rocchi L, Brown K, Di Santo A, Smith H, Peterchev AV, Rothwell JC, Hannah R.   +6 more
europepmc   +1 more source

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

Advanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones, Madeline Laude, Zeenat Oyebanji, Ruchi Birur, Andres Luengo Martinez, Isabelle Gilbert, Phillip Baek, Nichole Longbottom, Nicole McCullough, Staci J. Horn, Chien‐Yu Lin, Matthew J. Lohr, Fred Clubb, Manuel K. Rausch, Elizabeth Cosgriff‐Hernandez   +14 more
wiley   +1 more source

A Common Ancestry-Specific Sodium Channel Variant Increases Susceptibility to Drug-Induced QTc Prolongation: Evidence From a Large Biobank. [PDF]

Circulation
Stewart R, Lowery BD, Farber-Eger E, Wada Y, Roden DM, Wells QS, Davogustto G.   +6 more
europepmc   +1 more source

Lysosome‐Acidifying Nanoparticles Rescue A30P α‐Synuclein Induced Neuronal Death in Cellular and Drosophila Models of Parkinson's Disease

Advanced Healthcare Materials, EarlyView.
Lysosome‐targeted acidic nanoparticles based on a biodegradable poly(ethylene tetrafluorosuccinate‐co‐succinate) copolymer are engineered to restore impaired lysosomal acidification through pH‐responsive intracellular degradation. Localized acid release enhances autophagic proteolysis, reduces α‐synuclein accumulation, and preserves dopaminergic neuron
Chih Hung Lo, Mengda Ren, Gavin Wen Zhao Loi, Eka Norfaishanty Saipuljumri, Jonathan Indajang, Kah Leong Lim, Jialiu Zeng   +6 more
wiley   +1 more source

Machine learning analysis of ARVC informed by sodium channel protein-based interactome networks. [PDF]

Front Pharmacol
Zhu Y, Zhang H, Zhao X, Wang X, Xing L, Yao S, Jin X, Li T, Dai T, Ding X, Qi Z, Liu Z.   +11 more
europepmc   +1 more source

Aqueous Two‐Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells

Advanced Healthcare Materials, EarlyView.
Aqueous two‐phase systems (ATPS) enable the formation of biomimetic interfaces crucial for tissue engineering. However, clinical translation remains limited by the challenge of precisely controlling cellular compartmentalization. Here, we developed ATPS biomaterial inks for 3D bioprinting allowing tuneable droplet formation via NaCl modulation.
Martina Marcotulli, Arianna Iacomino, Federico Serpe, Lucia Iafrate, Marco Bastioli, Giorgia Montalbano, Biagio Palmisano, Silvia Franco, Roberta Angelini, Alessandro Corsi, Mara Riminucci, Giancarlo Ruocco, Chiara Scognamiglio, Andrea Barbetta, Gianluca Cidonio   +14 more
wiley   +1 more source

Flecainide mediated sodium channel blockade enhances blood brain barrier integrity and promotes neuroprotection in neuroinflammation. [PDF]

Sci Rep
Sindi M, Klees D, Dobelmann V, Disse P, Weigel H, Lichtenberg S, Ricci R, Thewes L, Deniz-Köseoglu G, Hecker C, Müntefering T, Issberner A, Gruchot J, Hartung HP, Ruck T, Berndt C, Kurz T, Stark H, Küry P, Engelhardt B, Lyck R, Meuth SG, Dietrich M, Albrecht P.   +23 more
europepmc   +1 more source