Results 291 to 300 of about 644,536 (348)
Pathophysiological Implications of Sodium Transporters and Water Channels in the Kidney
Soo‐Wan Kim +4 more
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Stable overexpression of the epithelial sodium channel alpha subunit reduces migration and proliferation in breast cancer cells. [PDF]
McQueen SRA +3 more
europepmc +1 more source
Normal locomotion in zebrafish lacking the sodium channel NaV1.4 suggests that the need for muscle action potentials is not universal. [PDF]
Akiyama C, Sakata S, Ono F.
europepmc +1 more source
The Effect of the R1648H Sodium Channel Mutation on Neuronal Excitability: A Model Study
Christopher Locandro, Robert Clewley
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Journal of Medicinal Chemistry, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Donald J, Kyle, Victor I, Ilyin
openaire +2 more sources
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Donald J, Kyle, Victor I, Ilyin
openaire +2 more sources
Current Opinion in Nephrology and Hypertension, 1994
The highly selective amiloride-sensitive epithelial sodium channel is expressed in the distal part of the nephron, the distal colon, and the lung. It plays a critical role in the control of sodium balance, extracellular volume, blood pressure, and of fluid reabsorption in the lung. The primary structure of the rat epithelial sodium channel has recently
B C, Rossier +3 more
openaire +2 more sources
The highly selective amiloride-sensitive epithelial sodium channel is expressed in the distal part of the nephron, the distal colon, and the lung. It plays a critical role in the control of sodium balance, extracellular volume, blood pressure, and of fluid reabsorption in the lung. The primary structure of the rat epithelial sodium channel has recently
B C, Rossier +3 more
openaire +2 more sources
Cardiac Sodium Channel Diseases
Clinical Chemistry and Laboratory Medicine, 2003In the last few years, a very active line of research took place after the first identification of SCN5A mutations associated with an inherited form of cardiac arrhythmias and sudden death, the LQT3 variant of the long QT syndrome. Subsequently, two allelic diseases additional to LQT3 were shown to be due to mutations in the same gene, the Brugada ...
Napolitano,C, Rivolta, I, Priori, SG
openaire +2 more sources
2017
Voltage-gated sodium channels (VGSC) are critical determinants of cellular electrical activity through the control of initiation and propagation of action potential. To ensure this role, these proteins are not consistently delivered to the plasma membrane but undergo drastic quality controls throughout various adaptive processes such as biosynthesis ...
Mercier, Aurélie +2 more
openaire +3 more sources
Voltage-gated sodium channels (VGSC) are critical determinants of cellular electrical activity through the control of initiation and propagation of action potential. To ensure this role, these proteins are not consistently delivered to the plasma membrane but undergo drastic quality controls throughout various adaptive processes such as biosynthesis ...
Mercier, Aurélie +2 more
openaire +3 more sources
Current Opinion in Pharmacology, 2015
Voltage-gated sodium channels play a key role in the transmission of sensory information about the status of organs in the periphery. Sensory fibers contain a heterogeneous yet specific distribution of voltage-gated sodium channel isoforms. Major efforts by industry and academic groups are underway to develop medicines that interrupt inappropriate ...
Kevin, Kwong, Michael J, Carr
openaire +2 more sources
Voltage-gated sodium channels play a key role in the transmission of sensory information about the status of organs in the periphery. Sensory fibers contain a heterogeneous yet specific distribution of voltage-gated sodium channel isoforms. Major efforts by industry and academic groups are underway to develop medicines that interrupt inappropriate ...
Kevin, Kwong, Michael J, Carr
openaire +2 more sources

