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Sodium Channel Blockers and Activators
2000Impulse conduction in brain and peripheral nerves, skeletal and cardiac muscle is sustained by transient increases in membrane permeability to sodium ions. This function resides in a family of integral membrane proteins, the voltage-gated Na+ channels.
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Sodium and Calcium Channel Blockers
2002The term “neuroprotection” means the pharmacologic prevention of the rapid (hours) or slower neuronal cell death caused by impaired blood flow or head trauma. Typically, neuroprotection is studied by acute drug treatment shortly after the insult in animal models of stroke, brain ischemia, or head trauma. The study of neuroprotection with organic cation
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Sodium channel blockers: a patent review (2010 – 2014)
Expert Opinion on Therapeutic Patents, 2015Mirko Rivara +2 more
exaly
Synthesis and evaluation of hermitamides A and B as human voltage-gated sodium channel blockers
Bioorganic and Medicinal Chemistry, 2011Manoj Patel +2 more
exaly
Efficacy of sodium channel blockers in SCN2A early infantile epileptic encephalopathy
Brain and Development, 2017Fabio Mosca +2 more
exaly

