Results 281 to 290 of about 511,275 (351)

A Novel Ubiquitin Ligase Adaptor PTPRN Suppresses Seizure Susceptibility through Endocytosis of Na_V1.2 Sodium Channels. [PDF]

Adv Sci (Weinh)
Wang Y, Yang H, Li N, Wang L, Guo C, Ma W, Liu S, Peng C, Chen J, Song H, Chen H, Ma X, Yi J, Lian J, Kong W, Dong J, Tu X, Shah M, Tian X, Huang Z.   +19 more
europepmc   +1 more source

Germanane Quantum Dots Promote Metabolic Reprogramming of Immune Cells Toward Regulatory T Cells and Suppress Inflammation In Vitro and In Vivo

Advanced Functional Materials, EarlyView.
Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava, Alireza Rafieerad, Weiang Yan, Keshav Narayan Alagarsamy, Qingdong Guan, Leena Regi Saleth, Michel Aliani, Sanjiv Dhingra   +7 more
wiley   +1 more source

Peripherally targeted analgesia via AAV-mediated sensory neuron-specific inhibition of multiple pronociceptive sodium channels. [PDF]

J Clin Invest
Shin SM, Itson-Zoske B, Fan F, Xiao Y, Qiu C, Cummins TR, Hogan QH, Yu H.   +7 more
europepmc   +1 more source

Copper Single‐Atom Decorated Microfibrous Catalysts for Continuous‐Flow Reduction of Nitroarenes

Advanced Functional Materials, EarlyView.
Herein, a Cu‐single‐atom decorated, microfibrous catalyst (Cu1/CMF) is fabricated for chemoselective reduction of nitroarenes, demonstrating a superior processing capacity of 1.92 mmol mgcat−1 h−1 and superior durability (≥ 25 cycles) in a continuous‐flow manner.
Jiahan Zhao, Yingshuang Li, Zhuoyuan Bi, Guanwu Lian, Guokang Chen, Pei Liu, Yuan Meng, Fangrun Jin, Xiaoxu Zhao, Zhonghua Li, Jianyong Feng, Jiangbo Xi, Zhongxin Chen   +12 more
wiley   +1 more source

Voltage-gated sodium channels in genetic epilepsy: up and down of excitability. [PDF]

J Neurochem
Rusina E, Simonti M, Duprat F, Cestèle S, Mantegazza M.   +4 more
europepmc   +1 more source

Impact of Surface Functionalization on NV Quantum Properties: Implications for Biosensing with Fluorescent Nanodiamonds

Advanced Functional Materials, EarlyView.
Fluorescent nanodiamonds (fNDs) have emerged as an invaluable quantum sensing platform for biological and biochemical systems. This paper investigates the influence of common surface functionalization strategies for bioconjugation on the quantum properties of nitrogen vacancy (NV) centers in nanodiamonds.
Anja Sadžak, Iván Pérez, Mateja Guimarães, Lukas Spantzel, Fedor Jelezko, Michael Börsch, Anke Krueger   +6 more
wiley   +1 more source

Controlled Movement of Soft Actuators using Multi‐Responsive Microgel Arrays and Microcirculatory Systems

Advanced Functional Materials, EarlyView.
Microscale hydrogels (microgels) feature improved mass transport characteristics supportive of fast actuation and chemical tunability amenable to programmed stimuli response. A unique soft actuator architecture is realized by encapsulating microgels in soft microcirculatory systems which enable the convenient delivery of liquid stimuli for powering and
Nengjian Huang, Brennan P. Watts, Stephen A. Morin   +2 more
wiley   +1 more source

Introducing Pure Calcium Orthophosphate Gels and Aerogels

Advanced Functional Materials, EarlyView.
The synthesis of calcium phosphate‐based gels and aerogels is reported, which exhibit highly porous structures built up of networks of nanoparticles. In case of amorphous aerogels, this leads to yet unmatched specific BET surface areas, making these materials especially interesting for biomedical applications.
Oliver Jeske, Dominik Zanker, Nina Ehlert, Bing‐Qiang Lu, Denis Gebauer   +4 more
wiley   +1 more source

A binding site for phosphoinositides described by multiscale simulations explains their modulation of voltage-gated sodium channels. [PDF]

Elife
Lin Y, Tao E, Champion JP, Corry B.
europepmc   +1 more source