Results 201 to 210 of about 1,776,084 (300)

SalT supplementation in Older adults with Orthostatic intolerance Disorders (STOOD) trial: a study protocol for a feasibility randomised controlled trial. [PDF]

Pilot Feasibility Stud
Reddin C, Smyth A, McDermott S, McDermott C, Mannion E, Davies N, Iglesias AA, Sheldon R, Canavan M, Kenny RA, O'Donnell M.   +10 more
europepmc   +1 more source

Ammonia Accumulation Drives Intervertebral Disc Degeneration by Triggering Ammonia‐Induced Cell Death Through Lysosome–Mitochondria Crosstalk

Cell Proliferation, EarlyView.
Mechanical strain disrupts the lysosome‐mitochondria axis via GLS1‐mediated ammonia toxicity, causing NP cell death and ECM breakdown in IVDD. CB839‐mediated GLS1 inhibition effectively rescues cellular homeostasis and alleviates disc degeneration.
Yang Zhang, Yucheng Gao, Shuhang Dong, Shuanggong Liu, Lei Liu, Ziyi Song, Jie Xu, Yijun Rong, Guangxu Song, Yingze Zhang, Dongjin Wu, Zengxin Gao   +11 more
wiley   +1 more source

Clinical comparison of mouthrinse and orodispersible film containing cystatins and a statherin‐derived peptide against initial dental erosion

European Journal of Oral Sciences, EarlyView.
Abstract This randomized crossover in vivo study compared the anti‐erosive efficacy of solution and orodispersible film (ODF) formulations containing three cystatins (CaneCPI‐5, MaquiCPI‐3, and CsinCPI‐2) combined with a statherin‐derived peptide (StN15pSpS).
Marília Afonso Rabelo Buzalaf, Even Akemi Taira, Gustavo Cassalate da Silva, Mariana Miranda de Brito, Talita Mendes Oliveira Ventura, Flávio Henrique‐Silva, João Guilherme Medeiros, Thiago Saads Carvalho, Andrea Soares da Costa Fuentes, Karina Fan, Reinaldo Marchetto, Adrian Lussi, Vinícius Taioqui Pelá   +12 more
wiley   +1 more source

Nutritional Status and Caregiver Knowledge in Pediatric Cystic Fibrosis Management. [PDF]

Nutrients
Subih HS, Khamis N, Obeidat BS, Rumman N, Alyahya L.   +4 more
europepmc   +1 more source

1H NMR metabolomics and lipidomics analysis of neutrophils reveals biomarkers of ageing, inflammageing and frailty

The FEBS Journal, EarlyView.
Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah, Grace Filbertine, Lucy Gill, Asangaedem Akpan, Marie M. Phelan, Helen Louise Wright   +5 more
wiley   +1 more source

Effectiveness of culturally adapted lifestyle intervention package on blood pressure: A systematic review. [PDF]

Public Health Pract (Oxf)
Mamun MAA, Orchi K, Chowdhury A, Choudhury SR, Haque MA.   +4 more
europepmc   +1 more source

Structural insights into xyloglucan recognition by an ABC transporter from a Gram‐positive, thermophilic bacterium

The FEBS Journal, EarlyView.
Athe_2052 is an ABC transporter substrate‐binding protein that recognizes xyloglucan heptasaccharide (XXXG), a soluble breakdown product of plant xyloglucan. The crystal structure of Athe_2052, together with binding assays and computational modeling, shows how XXXG is recognized by this sugar transporter.
Hansen Tjo, Virginia Jiang, Philip D. Jeffrey, Angela Zhu, A. James Link, Jerelle A. Joseph, Jonathan M. Conway   +6 more
wiley   +1 more source

Dietary modification and nutritional supplements for exercise-induced bronchoconstriction: a systematic review and meta-analysis. [PDF]

Front Physiol
Su M, Sun R, Shan C.
europepmc   +1 more source

Nutrient‐specific combinatorial secretion of GLP‐1 and neurotransmitters in the enteroendocrine L‐cell line GLUTag

The FEBS Journal, EarlyView.
Enteroendocrine L cells function as chemosensors in the intestine. Using the L‐cell line GLUTag, we show that distinct nutrients trigger different combinations of co‐secretion of GLP‐1 and neurotransmitters: D‐glucose evokes GLP‐1, glutamate, and ATP; L‐glutamine evokes GLP‐1 and glutamate; sucralose and butyrate evoke only GLP‐1.
Yo Ito, Kazuki Harada, Yuri Osuga‐Yoshiike, Masami Yokota Hirai, Tetsuya Kitaguchi, Takashi Tsuboi   +5 more
wiley   +1 more source

Creatinine Normalization Over-Corrects Urinary Electrolytes but Not Protein: Implications for Hydration Monitoring in Athletes. [PDF]

Metabolites
Alshuwaier GO.
europepmc   +1 more source