Results 41 to 50 of about 9,216 (139)

Synergistic inhibition of MEK/ERK and BRAF V600E with PD98059 and PLX4032 induces sodium/iodide symporter (NIS) expression and radioiodine uptake in BRAF mutated papillary thyroid cancer cells

Thyroid Research, 2018
Background and AimsThe activating mutation BRAFV600E is a frequent genetic event in papillary thyroid carcinomas (PTC). Mutation BRAFV600E is associated with the loss of a sodium/iodine symporter (NIS), and subsequent radioiodide-refractory (RAI ...
Honglai Zhang, Dong Chen
semanticscholar   +1 more source

Sodium Glucose Cotransporter 2 Inhibitors in the Treatment of Diabetes Mellitus: Cardiovascular and Kidney Effects, Potential Mechanisms, and Clinical Applications.

Circulation, 2016
Sodium-glucose cotransporter-2 (SGLT2) inhibitors, including empagliflozin, dapagliflozin, and canagliflozin, are now widely approved antihyperglycemic therapies. Because of their unique glycosuric mechanism, SGLT2 inhibitors also reduce weight.
H. Heerspink, B. Perkins, D. Fitchett, M. Husain, D. Cherney   +4 more
semanticscholar   +1 more source

Evaluation of potential sodium-iodide symporter (NIS) inhibitors using a secondary Fischer rat thyroid follicular cell (FRTL-5) radioactive iodide uptake (RAIU) assay

Archives of Toxicology, 2020
A. Buckalew, Jun Wang, A. Murr, C. Deisenroth, Wendy M. Stewart, T. Stoker, S. Laws   +6 more
semanticscholar   +1 more source

Combination Diuretic Therapy With Thiazides: A Systematic Review on the Beneficial Approach to Overcome Refractory Fluid Overload in Heart Failure. [PDF]

Cureus, 2023
Gogikar A, Nanda A, Janga LSN, Sambe HG, Yasir M, Man RK, Mohammed L.   +6 more
europepmc   +1 more source

Serotonin transporter–ibogaine complexes illuminate mechanisms of inhibition and transport

Nature, 2019
J. Coleman, Dongxue Yang, Zhiyu Zhao, Po-Chao Wen, C. Yoshioka, E. Tajkhorshid, E. Gouaux   +6 more
semanticscholar   +1 more source

Expanded high-throughput screening and chemotype-enrichment analysis of the phase II: e1k ToxCast library for human sodium-iodide symporter (NIS) inhibition

Archives of Toxicology, 2021
Jun Wang, A. Richard, A. Murr, A. Buckalew, Ryan R. Lougee, Mahmoud Shobair, D. Hallinger, S. Laws, T. Stoker   +8 more
semanticscholar   +1 more source

Calcineurin inhibitors block sodium-chloride cotransporter dephosphorylation in response to high potassium intake.

Kidney International, 2017
Wakana Shoda, Naohiro Nomura, Fumiaki Ando, Yutaro Mori, Takayasu Mori, E. Sohara, T. Rai, S. Uchida   +7 more
semanticscholar   +1 more source

Cationic Surfactant - Zn+2 Systems as Mixed Corrosion Inhibitors for Carbon Steel in a Sodium Chloride Corrosive Medium

, 2018
R. Hameed
semanticscholar   +1 more source

Chloride dipstick to rapidly estimate urine sodium during diuresis in acute heart failure. [PDF]

Pharmacotherapy
Shah V, Cordwin D, Hummel SL, Dorsch MP.
europepmc   +1 more source

A Systematic Review of Baseline Characteristics of Patients With Successful Decongestion on Combination Diuretic Therapy in Acute Decompensated Heart Failure (ADHF). [PDF]

Cureus
Tunuguntla MN, Chanti P, Nelogal SS, Maddala M, Polinati D, Lnu R, Khan A, Sahu S, Younas S.   +8 more
europepmc   +1 more source