Results 41 to 50 of about 14,950 (202)
Cryo-EM structure of the potassium-chloride cotransporter KCC4 in lipid nanodiscs. [PDF]
Cation-chloride-cotransporters (CCCs) catalyze transport of Cl- with K+ and/or Na+across cellular membranes. CCCs play roles in cellular volume regulation, neural development and function, audition, regulation of blood pressure, and renal function.
Brohawn, Stephen Graf+2 more
core +2 more sources
Effect of concentration on the thermodynamics of sodium chloride aqueous solutions in the supercooled regime [PDF]
Molecular Dynamics simulations are performed on two sodium chloride solutions in TIP4P water with concentrations c=1.36 mol/kg and c=2.10 mol/kg upon supercooling. The isotherms and isochoresplanes are calculated. The temperature of maximum density line and the limit of mechanical stability line are obtained from the analysis of the thermodynamic ...
arxiv +1 more source
BACKGROUND Radioiodine (RAI) is commonly used for thyroid cancer treatment, although its therapeutic benefits are restricted to iodine-avid tumors. The RAI-refractory disease develops with tumor dedifferentiation involving loss of sodium-iodine symporter
Alyaksandr V. Nikitski+3 more
semanticscholar +1 more source
3,3′-Methylenedisalicylic acid (MDS) was synthesized and ascertained on the basis of elemental analyses (C, H) and spectral measurements (IR, mass, 1H NMR, and UV–vis).
Ayman H. Ahmed, El-Sayed M. Sherif
semanticscholar +1 more source
This study confirmed the effect of sodium/iodine symporter (NIS) expression on existing drugs by in vitro and in vivo tests using cultured cell lines. The tumor growth inhibitory effect of sodium astatide ([211At]NaAt) was evaluated by in vitro and in ...
K. Kaneda-Nakashima+8 more
semanticscholar +1 more source
Three-dimensional Binary Superlattices of Oppositely-charged Colloids [PDF]
We report the equilibrium self-assembly of binary crystals of oppositely-charged colloidal microspheres at high density. By varying the magnitude of the charge on near equal-sized spheres we show that the structure of the binary crystal may be switched between face-centered cubic, cesium chloride and sodium chloride.
arxiv +1 more source
The Concise Guide to PHARMACOLOGY 2023/24:Introduction and Other Protein Targets [PDF]
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions ...
Ahlers-Dannen, Katelin E+49 more
core +2 more sources
Damage in porous media due to salt crystallization [PDF]
We investigate the origins of salt damage in sandstones for the two most common salts: sodium chloride and sulfate. The results show that the observed difference in damage between the two salts is directly related to the kinetics of crystallization and the interfacial properties of the salt solutions and crystals with respect to the stone. We show that,
arxiv +1 more source
The Use of LeuT as a Receptor Model for Antidepressant Development [PDF]
Selective serotonin re-uptake inhibitors (SSRIs) have been considered to be promising drugs in psychiatric practice because of their selectivity to serotonin re-uptake transporter (SERT).
Rustanti, L. (Lina)
core
Toxin Mediated Diarrhea in the 21st Century: The Pathophysiology of Intestinal Ion Transport in the Course of ETEC, V. cholerae and Rotavirus Infection [PDF]
An estimated 4 billion episodes of diarrhea occur each year. As a result, 2–3 million children and 0.5–1 million adults succumb to the consequences of this major healthcare concern.
Ahn+216 more
core +3 more sources