Results 41 to 50 of about 4,527 (133)

Construction of a Fluorescence‐Based Logic Gate Seeing the Effect of Perchlorate Ions on Hemicyanine Dye–β‐Cyclodextrin Complexes to Certify Safe Drinking Water

ChemistryOpen, Volume 14, Issue 10, October 2025.
A method to detect perchlorate ions and certify safe drinking water by constructing a fluorescence‐based logic gate considering the binding of a hemicyanine dye with β‐CD is presented. Perchlorate ions (ClO4−) are prevalent contaminants in the surface, and drinking water that disrupt thyroid function by competitively inhibiting the sodium‐iodide ...
Anusha C. M., Shalini Dyagala, Sairathna Choppella, Mahesh Kumar Ravva, Subit Kumar Saha   +4 more
wiley   +1 more source

Molecular mechanism of ligand recognition by membrane transport protein, Mhp1 [PDF]

, 2014
The hydantoin transporter Mhp1 is a sodium-coupled secondary active transport protein of the nucleobase-cation-symport family and a member of the widespread 5-helix inverted repeat superfamily of transporters.
A Peter Johnson, Alexander D Cameron, Colin WG Fishwick, David Drew, David J Sharples, Ekaterina Ivanova, Florian Brueckner, Joseph Lanigan, Katie J Simmons, Mark SP Sansom, Oliver Beckstein, Peter JF Henderson, Scott M Jackson, Simon G Patching, Simone Weyand, So Iwata, Tian Geng, Zsoldos Z   +17 more
core   +4 more sources

Shared Genetic Architecture Among Severe Mental Disorders: A System Biology Approach Based on Protein–Protein Interaction

Brain and Behavior, Volume 15, Issue 9, September 2025.
This study explores the genetic overlap among PTSD, MDD, BD, and SZ, revealing shared biological pathways and co‐expression networks. Functional enrichment analysis highlights common molecular mechanisms underlying these psychiatric disorders, providing insights into their comorbidity and potential avenues for targeted therapeutic strategies.
Hernan F. Guillen‐Burgos, Valentina Vanegas, Isabella Gonzalez, Ana M. Caicedo, Valentina Arango, Juan F. Galvez‐Florez, Juan‐Manuel Anaya, Roger S. McIntyre, Wilson Terán   +8 more
wiley   +1 more source

Transciptome Analysis Illuminates the Nature of the Intracellular Interaction in a Vertebrate-Algal Symbiosis [PDF]

, 2017
During embryonic development, cells of the green alga Oophila amblystomatis enter cells of the salamander Ambystoma maculatum forming an endosymbiosis.
Burns, John A., Hill, Elizabeth M., Kerney, Ryan R., Kim, Eunsoo, Zhang, Huanjia   +4 more
core   +2 more sources

Promising Prodiginins Biological Activities

Chemistry &Biodiversity, Volume 22, Issue 9, September 2025.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
wiley   +1 more source

RibM from Streptomyces davawensis is a riboflavin/roseoflavin transporter and may be useful for the optimization of riboflavin production strains [PDF]

, 2011
Background The bacterium Bacillus subtilis, which is not a natural riboflavin overproducer, has been converted into an excellent production strain by classical mutagenesis and metabolic engineering.
Sabrina Hemberger, Danielle B Pedrolli, Jürgen Stolz, Christian Vogl, Martin Lehmann, Matthias Mack   +5 more
core   +1 more source

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, Volume 12, Issue 29, August 7, 2025.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

Involvement of mitogen activated kinase kinase 7 intracellular signalling pathway in Sunitinib-induced cardiotoxicity [PDF]

, 2018
The tyrosine kinase inhibitor Sunitinib is used to treat cancer and is linked to severe adverse cardiovascular events. Mitogen activated kinase kinase 7 (MKK7) is involved in the development of cardiac injury and is a component of the c-Jun N-terminal ...
Afthab Hussain, Aggarwal, Akat, Babiarz, Bagga, Bello, Boehm, Care, Chang, Christopher Mee, Chu, Di Lorenzo, Doherty, Eaton, Ewer, Faivre, Fenton, Foltz, Force, Fujii, Gerczuk, Gharanei, Ghatalia, Guo, Guttilla, Hahn, Hao, Hardip Sandhu, Hasinoff, Hattori, Hayakawa, He, Helen Maddock, Henderson, Hikoso, Hu, Huang, Huynh, Ichijo, Ilyas, Iriyama, Izumiya, Jia, Kaiser, Karaman, Kataoka, Kataoka, Kataoka, Kataoka, Katoh, Khakoo, Kim, Kim, Kim, Krause, Lavine, Liu, Liu, Luo, Marques, Mima, Mitchell, Mooney, Morita, Nako, Nomura, Pan, Rosenkranz, Roskoski, Saitoh, Samantha Louise Cooper, Sandhu, Sandhu, Schmidinger, Schramek, Shah, Shukla, Song, Song, Sucharov, Sundarrajan, Takeda, Tang, Taniike, Thijs, Thum, Tijsen, Tobiume, Toldo, Volynets, Wang, Wang, Windak, Xiao, Xu, Yamaguchi, Zhang, Zhang   +97 more
core   +1 more source

Thiazide‐Induced Acute Interstitial Pancreatitis in a 55‐Year‐Old Male: A Rare Adverse Drug Reaction

Clinical Case Reports, Volume 13, Issue 8, August 2025.
ABSTRACT Acute pancreatitis is inflammation of the pancreas and is most commonly caused by gallstones, alcohol use, hyperlipidemia, or idiopathic. Drug‐induced acute pancreatitis is relatively rare and often under‐recognized; it accounts for 0.1%–2% of all cases. Among many drugs, thiazide diuretics are infrequently implicated but remain a known cause.
Kshitiz Pandey, Ashish Panday, Pratik Pandey, Anand Chaudhary, Sushmita Khanal   +4 more
wiley   +1 more source

Identifying and Prioritizing Chemicals with Uncertain Burden of Exposure: Opportunities for Biomonitoring and Health-Related Research. [PDF]

, 2019
BackgroundThe National Institutes of Health's Environmental influences on Child Health Outcomes (ECHO) initiative aims to understand the impact of environmental factors on childhood disease. Over 40,000 chemicals are approved for commercial use.
(Environmental influences on Child Health Outcomes), Beamer, Paloma I, Bennett, Deborah H, Boyles, Rebecca R, Buckley, Jessie P, Kannan, Kurunthachalam, Pellizzari, Edo D, Wang, Aolin, Woodruff, Tracey J, Zhu, Yeyi   +9 more
core