Results 151 to 160 of about 883,391 (302)

SIRT7‐Mediated H2BK120 Succinylation Drives Aberrant Mitophagy in Sepsis‐Associated Cognitive Dysfunction

Advanced Science, EarlyView.
Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng, Jiateng Zhou, Xiaoyu Guo, Ting Hong, Xuelian Li, Xingyu Wei, Chanhua Zhang, Xixue Zhang, Songbin Liu, Yulin Zhang, Liangfang Yao, Lina Huang, Weidong Gu   +12 more
wiley   +1 more source

Vesicular melatonin efficiently downregulates sodium fluoride-induced rat hepato- and broncho- TNF-α, TGF-β expressions, and associated oxidative injury: a comparative study of liposomal and nanoencapsulated forms

, 2017
Suvomoy Sana, Swarupa Ghosh, Nirmalendu Das, Sibani Sarkar, Ardhendu Kumar Mandal Drug Development, Diagnostics and Biotechnology, CSIR-Indian Institute of Chemical Biology, West Bengal, India Abstract: The importance of fluoride as a natural and ...
Ghosh S, Sarkar S, Mandal AK, Sana S, Das N   +4 more
core  

Effects of Stannous and Sodium Fluoride on Human Gingival Fibroblasts.

PosterBackground: Periodontal diseases are inflammatory conditions of the tooth supporting tissues. Although bacterial byproducts have been linked to periodontal diseases, host responses have also been implicated.
Windsor, L. Jack, Mummert, Lauren
core   +1 more source

Probing the Energy Landscape of α‐Synuclein Amyloid Fibril Formation by Systematic K‐to‐Q Mutagenesis

Advanced Science, EarlyView.
We use lysine‐to‐glutamine mutations to study the effect of electrostatics on the kinetics and thermodynamics of alpha‐synuclein amyloid fibril formation. We find that mutational effects map on their structural context within fibrils and identify residues that modulate the energy landscape of alpha‐synuclein self‐assembly. Our work outlines a scalable,
Antonin Kunka, Azad Farzadfard, Jacob Aunstrup Larsen, Rasmus Krogh Norrild, Federica Saraceno, Celia Fricke, Hossein Mohammad‐Beigi, Ahmed Sadek, Jonas Folke, Susana Aznar, Alexander K. Buell   +10 more
wiley   +1 more source

The influence of saliva on the dissolution of calcium fluoride after application of different fluoride gels in vitro

, 2010
OBJECTIVE: To determine the formation and dissolution of calcium fluoride on the enamel surface after application of two fluoride gel-saliva mixtures. METHOD AND MATERIALS: From each of 80 bovine incisors, two enamel specimens were prepared and subjected
Hellwig, Elmar, Lussi, Adrian, Polydorou, Olga, Kielbassa, Andrej M, Altenburger, Markus J   +4 more
core  

Effect of a sodium fluoride rinse on the composition of early oral biofilms formed in situ on enamel and dentine. [PDF]

Clin Oral Investig
Berto LP, Ding J, Sakae LO, Niemeyer SH, Wierichs RJ, Ricomini-Filho AP, Meyer-Lueckel H, Baumann T, Carvalho TS.   +8 more
europepmc   +1 more source

Sodium Fluoride and Cell Growth [PDF]

BMJ, 1963
R J, BERRY, W, TRILLWOOD
openaire   +4 more sources

Sequential Regulation of Neurovascular Bone Regeneration in Large Bone Defects Using Black Phosphorus‐Europium Nanosheet Integrated TPMS Biomimetic Scaffold with Photo‐Controlled Ion Release

Advanced Science, EarlyView.
TPBE scaffolds, in conjunction with mild photothermal effects, effectively activate the PI3K/Akt signaling cascade, thereby promoting early neuronal differentiation and neurite growth. Short‐term (12 W) in vivo implantation studies revealed no significant pathological damage to major organs, providing preliminary evidence of the material's excellent ...
Bingqian Wang, Yuping Zhang, Xiaoning Su, Ning Liu, Hui Zeng, Bo Yang, Yang Xue, Fang Guo, Changkui Liu   +8 more
wiley   +1 more source

Fluoride and phosphate release from fluoride varnishes supplemented with nano-sized sodium trimetaphosphate

Purpose: The addition of sodium trimetaphosphate (TMP) to fluoride (F) varnishes has been shown to be effective in controlling dental caries and erosive tooth wear.
Delbem, Alberto Carlos Botazzo [UNESP], Monteiro, Douglas Roberto, Hosida, Thayse Yumi [UNESP], Pessan, Juliano Pelim [UNESP], Sampaio, Caio [UNESP], Báez-Quintero, Liliana Carolina [UNESP], Nagata, Mariana Emi [UNESP], Castro E Silva, Malena Morais [UNESP]   +7 more
core  

Is There a Role for Sodium Fluoride in Otosclerosis Treatment? [PDF]

Laryngoscope
Shim T, Wong K, Ruckenstein MJ.
europepmc   +1 more source