Results 131 to 140 of about 883,391 (302)
The molecular mechanism of fluoride export by the eukaryotic fluoride channel FEX
Nature CommunicationsMuch of life on Earth, including plants, fungi, and bacteria, evolved to resist toxic environmental fluoride. In eukaryotes, the major resistance mechanism is fluoride export by membrane proteins known as FEX. Using electrophysiology and transport assays,
Chia-Yu Kang +5 more
doaj +1 more source
Advanced Science, EarlyView.This study uncovers that KP1, a Klotho‐derived peptide, protects the kidney against acute kidney injury, a clinical syndrome with high morbidity and mortality. KP1 enters tubular epithelial cells via endocytosis, directly interacts with the mitochondrial ATAD3A/HIGD2A complex, thereby preventing cytochrome c release, and caspases activation, and ...
Xiaoyao Zhang +6 more
wiley +1 more source
Advanced Science, EarlyView.An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang +8 more
wiley +1 more source
Selective Modulation of OTUB1 Noncanonical Function via a bioPhosTAC Strategy
Advanced Science, EarlyView.This work positions the versatile performance of the peptide‐based bioPhosTAC platform for dissecting phosphorylation‐dependent biology and expanding the scope of induced‐proximity technologies. We demonstrated that selective manipulation of a tyrosine phosphorylation site is sufficient to propagate coordinated cellular consequences.
Seung Un Seo +7 more
wiley +1 more source
Unveiling a Near‐Total Rear Passivation for High Performance of Ultra‐Thin ACIGS
Advanced Science, EarlyView.Ultra‐thin solar cells of (Ag,Cu)(In,Ga)Se2 (ACIGS) suffer from rear interface recombination, limiting their performance. To tackle it, a full coverage plasma enhanced chemically vapor‐deposited 8 nm porous SiOx passivation layer was implemented and evaluated. It is shown that a combination of the near‐complete passivation from silica and the formation
Xavier L. Pinheiro +7 more
wiley +1 more source
Geometry‐Regulated Electrode‐Wide Nucleation Patterns in Aqueous Zinc Anodes
Advanced Science, EarlyView.Laser‐ablated 3D hole patterning enables geometry‐driven control of Zn deposition in aqueous batteries. The hole opening ratio (HOR) governs electrode‐wide nucleation patterns by regulating the spatial distribution of nucleation sites and the evolution of early‐stage Zn deposits.
Seyoung Han +4 more
wiley +1 more source
Purpose: Fluoride is a common environmental contaminant that, when consumed in high amounts, can cause oxidative damage and inflammation, leading to serious dysfunction in vital organs such as the liver, kidneys, and heart.
Sevda, İnan, Arslan, Sezai
core
α‐Synuclein Forms Distinct Micelle‐Like Assemblies at Low Ionic Strengths
Advanced Science, EarlyView.At high ionic strength, α‐synuclein forms diverse assemblies, including oligomers, fibrils, and condensates. Here, we show that at low ionic strength, α‐synuclein adopts a distinct, low‐abundance assembly state. These assemblies maintain a constant size above a critical concentration and do not coalesce, suggesting a micelle‐like organization ...
Sophie Hertel +10 more
wiley +1 more source
Purpose: The aim of this study was to evaluate parental attitudes, perceptions and sources of information regarding fluoride toothpastes and topical fluoride applications. Methods: This study was designed as a cross-sectional questionnaire.
Kockanat, Arzu
core
Проблеми екології та медицини, 2017 The effect of small subtoxic doses of sodium fluoride on the antioxidant activity of the liver has been studied in Wistar rats populations in the subacute experiment.
I.L. Kolisnyk
doaj