Results 91 to 100 of about 239,405 (357)

Blunted Cystine–Glutamate Antiporter Function in the Nucleus Accumbens Promotes Cocaine-induced Drug Seeking [PDF]

, 2008
Repeated cocaine alters glutamate neurotransmission, in part, by reducing cystine–glutamate exchange via system xc−, which maintains glutamate levels and receptor stimulation in the extrasynaptic compartment.
Abdulhameed, Omer, Baker, David A., Grier, Mark D., Kau, Kristen S., Madayag, Aric, Mantsch, John R.   +5 more
core   +1 more source

EFFECTS OF SODIUM GLUTAMATE ON THE NERVOUS SYSTEM

The Keio Journal of Medicine, 1954
1) High concentration of sodium glutamate (as well as sodium aspartate) which is applied into grey matters of motor cortex in dogs, monkeys and men, generates clonic convulsions with very short latent periods.2) Small dose of sodium glutamate which is introduced into circulation in dogs improves the differentiation of conditioned salivary reflexes ...
openaire   +3 more sources

Structure and Electrochemical Properties of ReS2‐LaFeO3 Nanocomposite for Dopamine Sensing

Advanced Sensor Research, EarlyView.
A novel ReS2‐LaFeO3 nanocomposite is developed for sensitive and reliable detection of dopamine (DA), an important neurotransmitter. The material performs well even in complex biological samples, demonstrating strong selectivity and accuracy. These findings highlight its potential for future applications in medical diagnostics and neuroscience research.
Obed Graham Keelson, Rajeev Kumar, Amit Kumar Shringi, Hazel Achieng Ouma, Pooja D. Walimbe, Fei Yan   +5 more
wiley   +1 more source

Cyclooxygenase Inhibitors Attenuate Augmented Glutamate Release in Organum Vasculosum Laminae Terminalis and Fever Induced by Staphylococcal Enterotoxin A

Journal of Pharmacological Sciences, 2004
Both the hyperthermia and augmented glutamate release in the organum vasculosum laminae terminalis (OVLT) after an intravenous dose (30 ng/kg) of staphylococcal enterotoxin A (SEA) were significantly reduced by pretreatment with intravenous ...
Wu-Tein Huang, Jhi-Joung Wang, Mao-Tsun Lin   +2 more
doaj  

Circadian Regulation of Glutamate Transporters

Frontiers in Endocrinology, 2018
L-glutamate is the major excitatory amino acid in the mammalian central nervous system (CNS). This neurotransmitter is essential for higher brain functions such as learning, cognition and memory.
Donají Chi-Castañeda, Arturo Ortega
doaj   +1 more source

Reduction in Phencyclidine Induced Sensorimotor Gating Deficits in the Rat Following Increased System Xc − Activity in the Medial Prefrontal Cortex [PDF]

, 2013
Rationale: Aspects of schizophrenia, including deficits in sensorimotor gating, have been linked to glutamate dysfunction and/or oxidative stress in the prefrontal cortex. System xc −, a cystine–glutamate antiporter, is a poorly understood mechanism that
A Araque, A Kulak, A Wilmsmeier, B Moghaddam, B Moghaddam, B Oranje, BJ Morris, D Braff, D Lobner, D Matsuzawa, D Piani, DA Baker, DA Baker, David A. Baker, DH Ingvar, DL Braff, DV Pow, FK Graham, G Battaglia, G Franzen, G Paxinos, G Paxinos, G Rajkowska, HH Chen, J Cilia, JA Lieberman, JH Cabungcal, JI Sagara, Jon Resch, JT Coyle, K Japha, K Moussawi, K Moussawi, K Ogita, K Schwabe, K Shimosato, KE Poskanzer, KF Berman, KQ Do, Krista Qualmann, KS Kau, L Deserno, L Pasti, LA Glantz, Linghai Kong, LJ Garey, M Berk, M Berk, M Koch, M Li, M Raffa, MA Geyer, MC Angulo, ME Jackson, MJ Marino, MM Moran, NA Oberheim, NM Veelen van, NR Swerdlow, NR Swerdlow, NR Swerdlow, NR Swerdlow, O Kranich, P Bezzi, P Steullet, R Bridges, R Gysin, R Janaky, S Bannai, S Bannai, S Bannai, SG Potkin, SuJean Choi, T Majic, V Kumari, V Parpura, Victoria Lutgen, VM Goghari, VP Bakshi, WE Bunney, Y Cho, ZC Ye   +81 more
core   +2 more sources

Automated Transcranial Photobiomodulation in Healthy Rats: Effects on Working Memory and Brain Markers

Advanced Therapeutics, EarlyView.
Transcranial photobiomodulation (PBM) enhances spatial working memory in healthy rats under both continuous and alternating stimulation protocols. At the neural level, PBM modulates cytochrome c oxidase activity, increases prefrontal and hippocampal synaptic markers, and induces region‐specific c‐Fos expression. These effects suggest improved cognitive
Candela Zorzo, Lucía Rodríguez‐Fernández, Emily Gabriela Castillo‐Escalona, Juan A. Martínez, Laura Mañas, Natalia Arias, Jorge L. Arias   +6 more
wiley   +1 more source

LRRC8A Regulates Outer Hair Cell Volume and Electromotility and is Required for Hearing

Advanced Science, EarlyView.
This study identifies LRRC8A‐dependent volume‐regulated anion channels (VRACs) as essential for cochlear outer hair cells' electromotility and auditory signal amplification. LRRC8A deficiency disrupts cell volume control, impairs auditory sensitivity, and causes deafness, while targeted LRRC8A re‐expression restores auditory function.
Shengnan Wang, Yuehui Xi, Qiaojun Fang, Sai Shi, Fei Wang, Fuyu Xian, Zhongyang Zhang, Yuxin Yang, Xishuo Jin, Xiaomin Wang, Chen Cao, Hailin Zhang, Nikita Gamper, Zhigang Xu, Haitao Shen, Ping Lv   +15 more
wiley   +1 more source

Neuronal and astroglial correlates underlying spatiotemporal Intrinsic Optical Signal in the rat hippocampal slice [PDF]

, 2013
Widely used for mapping afferent activated brain areas in vivo, the label-free intrinsic optical signal (IOS) is mainly ascribed to blood volume changes subsequent to glial glutamate uptake.
Héja, László, Kardos, Julianna, Nyitrai, Gabriella, Pál, Ildikó   +3 more
core   +3 more sources

Reduction of sodium content in spicy soups using monosodium glutamate

Food & Nutrition Research, 2016
Excessive dietary sodium intake causes several diseases, such as hypertension, cardiovascular and renal disease, etc. Hence, reducing sodium intake has been highly recommended. In this study the effect of monosodium glutamate (MSG), as an umami substance, on saltiness and sodium reduction was investigated.The trained panellists were presented with ...
Jinap, Selamat, Hajeb, Parvaneh, Karim, Roslina, Norliana, Sarian, Yibadatihan, Simayi, Abdul-Kadir, Razak   +5 more
openaire   +6 more sources