Results 91 to 100 of about 149,737 (259)

Targeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety

open access: yesAdvanced Science, EarlyView.
Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li   +10 more
wiley   +1 more source

From Materials to Systems: Challenges and Solutions for Fast‐Charge/Discharge Na‐Ion Batteries

open access: yesAdvanced Energy Materials, EarlyView.
This review systematically analyzes the key characteristics limiting the fast‐charge/discharge capability of Na‐ion batteries (SIBs) from a multi‐scale perspective encompassing electrode materials, the electrode‐electrolyte interface, and the system. Furthermore, it presents practical solution strategies for the fundamental issues arising at each scale,
Bonyoung Ku   +5 more
wiley   +1 more source

Interaction Study between Umami and Salty Based on Electronic Tongue Technology and σ-τ Model

open access: yesShipin gongye ke-ji
Salt and salty foods play a crucial role in enhancing flavor and are integral to traditional cuisine. Salt control and intake reduction are particularly important in a sodium reduction policy. To investigate the relationship between umami ingredients and
Linxue DAI   +4 more
doaj   +1 more source

Comparative Insights and Overlooked Factors of Interphase Chemistry in Alkali Metal‐Ion Batteries

open access: yesAdvanced Energy Materials, EarlyView.
This review presents a comparative analysis of Li‐, Na‐, and K‐ion batteries, focusing on the critical role of electrode–electrolyte interphases. It especially highlights overlooked aspects such as SEI/CEI misconceptions, binder effects, and self‐discharge relevance, emphasizing the limitations of current understanding and offering strategies for ...
Changhee Lee   +3 more
wiley   +1 more source

Multipathway modulation of neuroinflammation and oxidative stress by hesperidin in a rat single prolonged stress model of post‐traumatic stress disorder

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Single prolonged stress (SPS) induces post‐traumatic stress disorder (PTSD)‐like neuropathology characterized by oxidative stress, neuroinflammation, astrocytic reactivity, neuronal damage, and reduced neurotrophic support in the hippocampus, amygdala, and prefrontal cortex. Hesperidin counteracts these effects by attenuating lipid peroxidation and pro‐
Godson Emeka Anyanwu   +6 more
wiley   +1 more source

The diagnostic value of the circadian rhythm gene KLF10 in anxiety‐depressive disorders and its neuroimmune regulatory mechanisms

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the protective role and molecular mechanism of the circadian rhythm‐related gene KLF10, identified as a diagnostic biomarker and therapeutic target in anxiety‐depressive disorder. Model establishment and phenotypes: An anxiety‐depression model was successfully established by chronic restraint stress combined with ...
Anlan Liu   +4 more
wiley   +1 more source

NaHS modulates astrocytic EAAT2 expression to impact SNI-induced neuropathic pain and depressive-like behaviors

open access: yesScientific Reports
The potential role of hydrogen sulfide (H2S) in the modulation of neuropathic pain is increasingly recognized. This study investigated the therapeutic effect of intraperitoneal injection of the H2S donor sodium hydrosulfide (NaHS) on neuropathic pain ...
Man-Man Qi   +6 more
doaj   +1 more source

EFFECTS OF SODIUM GLUTAMATE ON HUMAN AND ANIMAL

open access: yesBulletin of Problems Biology and Medicine, 2021
O. V. Kinash   +6 more
openaire   +1 more source

Evaluation of Sodium Poly- , L-glutamate as a Plasma Expander.

open access: yesExperimental Biology and Medicine, 1959
Summary(1) A synthetic polypeptide, sodium poly-α, L-glutamate (SPG), has been evaluated as a plasma expander by comparing it with dextran in both normovolemic and hypovolemic dogs. (2) SPG at a concentration of 3% was equivalent to 6% dextran as a plasma expander. (3) Further studies with SPG proved it to be too toxic for clinical trial.
openaire   +2 more sources

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