Results 121 to 130 of about 239,405 (357)
Transient astrocytic accumulation of fluorescein during spreading depolarizations
Neurobiology of Disease, 2023 Spreading depolarizations (SDs) occur frequently in acute cerebral injuries. They are characterized by a breakdown of transmembrane ion gradients resulting in a reduced extracellular sodium ([Na+]o) and increased extracellular potassium concentration ([K+
Karl Schoknecht +2 more
doaj
Journal of Venomous Animals and Toxins including Tropical Diseases, 2009 TsTX is an α-type sodium channel toxin that stimulates the discharge of neurotransmitters from neurons. In the present study we investigated which neurotransmitters are released in the hippocampus after TsTX injection and if they are responsible for
ALA Nencioni +5 more
doaj +1 more source
⁹⁹ᵐTc SPECT imaging agent based on cFLFLFK for the detection of FPR1 in inflammation [PDF]
, 2015 Non-invasive imaging of the inflammatory process can provide a great deal of insight into a wide variety of diseases states, aiding diagnosis, evaluation and effective targeted treatment. During inflammation, blood borne leukocytes are recruited, through
Gavins, Felicity N.E. +7 more
core +2 more sources
EFFECT OF SODIUM GLUTAMATE ON THE DIGESTIVE ORGANS
Bulletin of Problems Biology and Medicine, 2021 N. A. Ulanovskaya–Tsyba +5 more
openaire +1 more source
Parasubthalamic Glutamatergic Neurons Coordinate Cardiovascular Homeostasis and Locomotion in Mice
Advanced Science, EarlyView.PSTNVglut2 neurons function as a new central baroreflex hub via projections to the NTS, modulating parasympathetic cardiac output to maintain cardiovascular homeostasis while synchronously regulating locomotion. Blood pressure fluctuations negatively correlate with locomotor performance.
Ming‐Xuan Lu +8 more
wiley +1 more source
Hypoxic injury of isolated axons is independent of ionotropic glutamate receptors
Neurobiology of Disease, 2007 Axonal injury in white matter is an important consequence of many acute neurological diseases including ischemia. A role for glutamate-mediated excitotoxicity is suggested by observations from in vitro and in situ models that AMPA/kainate blockers can ...
Suzanne M. Underhill, Mark P. Goldberg
doaj
Acid-Sensing Ion Channels Activated by Evoked Released Protons Modulate Synaptic Transmission at the Mouse Calyx of Held Synapse [PDF]
, 2017 Acid-sensing ion channels (ASICs) regulate synaptic activities and play important roles in neurodegenerative diseases. We found that these channels can be activated in neurons of the medial nucleus of the trapezoid body (MNTB) of the auditory system in ...
Di Guilmi, Mariano Nicolás +3 more
core +1 more source
EFFECTS OF SODIUM GLUTAMATE ON HUMAN AND ANIMAL
Bulletin of Problems Biology and Medicine, 2021 I. M. Donets +6 more
openaire +1 more source
Advanced Science, EarlyView.Elevated lactate in diabetes activates the GPR132‐Src pathway in macrophages, inducing macrophage senescence and further enhancing foam cell formation. This mechanism exacerbates atherosclerotic progression. Abstract Diabetes is widely acknowledged as a significant risk factor for atherosclerosis, facilitating plaque formation through various ...
Xiaofeng Ge +10 more
wiley +1 more source
Cellular Physiology and Biochemistry, 2017 Background/Aims: Inborn deficiency of the N-acetylglutamate synthase (NAGS) impairs the urea cycle and causes neurotoxic hyperammonemia. Oral administration of N-carbamoylglutamate (NCG), a synthetic analog of N-acetylglutamate (NAG), successfully ...
Birgitta C. Burckhardt +1 more
doaj +1 more source