Impact of Co-Excipient Selection on Hydrophobic Polymer Folding: Insights for Optimal Formulation Design [PDF]
The stabilization of liquid biological products is a complex task that depends on the chemical composition of both the active ingredient and any excipients in solution. Frequently, a large number of unique excipients are required to stabilize biologics, though it is not well-known how these excipients interact with one another. To probe these excipient-
arxiv
Three phases in the evolution of the standard genetic code: how translation could get started [PDF]
A primordial genetic code is proposed, having only four codons assigned, GGC meaning glycine, GAC meaning aspartate/glutamate, GCC meaning alanine-like and GUC meaning valine-like. Pathways of ambiguity reduction enlarged the codon repertoire with CUC meaning leucine, AUC meaning isoleucine, ACC meaning threonine-like and GAG meaning glutamate ...
arxiv
Evaluation of Sodium Poly- , L-glutamate as a Plasma Expander.
Summary(1) A synthetic polypeptide, sodium poly-α, L-glutamate (SPG), has been evaluated as a plasma expander by comparing it with dextran in both normovolemic and hypovolemic dogs. (2) SPG at a concentration of 3% was equivalent to 6% dextran as a plasma expander. (3) Further studies with SPG proved it to be too toxic for clinical trial.
openaire +3 more sources
Vinyl Polymerization. CCCLXXXV. Polymerization of Methyl Methacrylate Initiated with Sodium Poly(L-glutamate) in Aqueous Medium of Cu(II) Ion [PDF]
Tatsuro Ouchi+4 more
openalex +1 more source
Saccharomyces boulardii, as a probiotic yeast, had been commonly used in food, medicine and feed to treat diarrhea in humans or livestock. However, there are few researches focusing on the preparation of its freeze-drying S.boulardii powder.
Shu Guowei+4 more
doaj +1 more source
Studies on Bacterial Density of Environmental Air by Sodium Glutamate Filter Method
Nobuo Samori
openalex +4 more sources
In-vitroClot Forming Properties of Polyelectrolyte Complexes of [2-(Diethylamino)ethyl]dextran Hydrochloride with Poly(sodium-L-glutamate) and of Sodium Carboxymethyldextran with Chitosan [PDF]
Yasuo Kikuchi, Tsutomu Takebayashi
openalex +1 more source
Deletion of the Sodium-Dependent Glutamate Transporter GLT-1 in Maturing Oligodendrocytes Attenuates Myelination of Callosal Axons During a Postnatal Phase of Central Nervous System Development [PDF]
Elizabeth J. Thomason+5 more
openalex +1 more source
Transport of BMAA into Neurons and Astrocytes by System x\u3csub\u3ec\u3c/sub\u3e- [PDF]
The study of the mechanism of β-N-methylamino-l-alanine (BMAA) neurotoxicity originally focused on its effects at the N-methyl-d-aspartate (NMDA) receptor. In recent years, it has become clear that its mechanism of action is more complicated.
Albano, Rebecca, Lobner, Doug
core +1 more source