Fabrication and Functionalisation of Nanocarbon‐Based Field‐Effect Transistor Biosensors
ChemBioChem, Volume 23, Issue 23, December 5, 2022., 2022 Next‐generation diagnostics: Nanocarbon‐based field effect transistors (NC‐FETs) use incoming target analytes to impart a gating effect on conductance. Here, we review the operational mechanisms behind NC‐FETs, the fabrication and functionalisation of NC‐FETs with receptor biomolecules and downstream biosensing applications.
Chang‐Seuk Lee +4 more
wiley +1 more source
A theoretical study of the role of astrocyte activity in neuronal hyperexcitability using a new neuro-glial mass model [PDF]
arXiv, 2015 The investigation of the neuronal environment allows us to better understand the activity of a cerebral region as a whole. The recent experimental evidences of the presence of transporters for glutamate and GABA in both neuronal and astrocyte compartments raise the question of the functional importance of the astrocytes in the regulation of the ...
arxiv
EFFECTS OF SODIUM GLUTAMATE ON HUMAN AND ANIMAL
Bulletin of Problems Biology and Medicine, 2021 I. M. Donets +6 more
openaire +1 more source
Advanced Science, EarlyView.The study reveals that glutaminolysis in macrophages is inhibited under type 2 diabetes mellitus (T2DM) conditions, which impedes fracture healing by reducing bone morphogenetic protein 2 (BMP2) production through increased cytosine methylation on the promoter.
Jing Wang +12 more
wiley +1 more source
Chemical Proteomics Reveals Protein Tyrosination Extends Beyond the Alpha‐Tubulins in Human Cells**
ChemBioChem, Volume 23, Issue 23, December 5, 2022., 2022 Protein post‐translational modifications allow cells to swiftly adjust activity and localization of proteins. Here, we developed a chemical proteomic approach to determine a protein tyrosination status using an O‐propargyl tyrosine probe. We show that tyrosination modifies previously described alpha‐tubulins with ‐EEY C‐terminal sequence together with ...
Dmytro Makarov, Pavel Kielkowski
wiley +1 more source
Does a glycine sodium nitrite crystal exist? [PDF]
arXiv, 2015 The glycine sodium nitrite crystal reported by Khandpekar and Pati in the paper entitled, Synthesis and characterisation of glycine sodium nitrite crystals having non linear optical behaviour, Opt Commun 285, 2012 288-293 is actually gamma-glycine. In addition, we show that glycine barium ammonium nitrate, glycine sodium zinc sulfate, glycine barium ...
arxiv
The specific requirement for sodium chloride for the active uptake of
, 1966 Joann Stevenson
openalex +1 more source
Does GDNF exert its neuroprotective effects on photoreceptors in the rd1 retina through the glial glutamate transporter GLAST? [PDF]
, 2005 PURPOSE: We previously demonstrated that exogenous glial cell line-derived neurotrophic factor (GDNF) induces histological and functional protection of photoreceptors in the retinal degeneration (rd1) mouse model.
Delyfer, MN +4 more
core
Inhibition of Ferroptosis Delays Aging and Extends Healthspan Across Multiple Species
Advanced Science, EarlyView.This study identifies ferroptosis as a key driver of cellular senescence, with its inhibition delaying aging and extending healthspan across species. During senescence, ferroptosis worsens, increasing oxidative stress and lipid peroxidation, which accelerate aging.
Hai‐Jun Fu +15 more
wiley +1 more source
Structural and dynamical properties of sodium silicate melts: An investigation by molecular dynamics computer simulation [PDF]
Chem. Geol. 174, 87-101 (2001), 1999 We present the results of large scale computer simulations in which we investigate the static and dynamic properties of sodium disilicate and sodium trisilicate melts. We study in detail the static properties of these systems, namely the coordination numbers, the temperature dependence of the Q^(n) species and the static structure factor, and compare ...
arxiv