Results 191 to 200 of about 239,405 (357)

Activity dependent internalization of the glutamate transporter GLT-1 requires calcium entry through the NCX sodium/calcium exchanger [PDF]

open access: green, 2018
Ignacio Ibáñez   +4 more
openalex   +1 more source

Harnessing the Biological Responses Induced by Nanomaterials for Enhanced Cancer Therapy

open access: yesAggregate, EarlyView.
Nanomaterial (NM)‐induced toxicity can be strategically repurposed for cancer therapy. This review summarizes the mechanism by which NMs selectively activate specific cellular processes to regulate cell fate independently. We also discussed how NMs‐induced biological responses can be leveraged as therapeutic strategies for cancer treatment.
Liting Wang   +6 more
wiley   +1 more source

Genome‐Wide Insights and Polygenic Risk Scores in Common Epilepsies: A Narrative Review

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT The research of single gene‐related disorders or pathogenic copy‐number variations (CNVs) has given a significant impetus to the shift from a diagnostic work‐up focused on epileptic syndromes to genomic approaches in individuals with severe pediatric‐onset epilepsies and in developmental and epileptic encephalopathies.
Mario Mastrangelo   +5 more
wiley   +1 more source

Sodium-Dependent Glutamate Uptake by an Alkaliphilic, Thermophilic Bacillus Strain, TA2.A1

open access: bronze, 1999
Catherine J. Peddie   +2 more
openalex   +1 more source

Self‐Administered Taste Testing Without Water: Normative Data for the 53‐Item Waterless Empirical Taste Test (WETT)

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background According to the National Health and Nutrition Examination Survey (NHANES), more than 20 million Americans suffer from chronic taste problems. Unfortunately, quantitative testing is rarely performed, self‐reports are inaccurate, and “taste” is often confused with olfaction‐dependent flavors.
Richard L. Doty   +2 more
wiley   +1 more source

The cumulative analgesic effect of repeated electroacupuncture is modulated by Adora3 in the SCDH of mice with neuropathic pain

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Neuropathic pain management via repeated electroacupuncture. Abstract Background Existing remedial approaches for relieving neuropathic pain (NPP) are challenging and open the way for alternative therapeutic measures such as electroacupuncture (EA). The mechanism underlying the antinociceptive effects of repeated EA sessions, particularly concerning ...
Faisal Ayub Kiani   +6 more
wiley   +1 more source

Brassinin from Brassica campestris L. inhibits colorectal cancer by inducing p62/NRF2/GPX4‐regulated ferroptosis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
BSN suppresses the cell viability of colorectal cancer by inducing GPX4‐regulated ferroptosis. BSN may bind to NRF2 protein to inactivate the NRF2 signaling, inhibiting the expression of p62 and HO‐1. Abstract Background Indole phytoalexins, plant‐derived compounds present in cruciferous vegetables, have demonstrated anticancer properties.
Shi‐Yuan Wen   +5 more
wiley   +1 more source

The sodium-glutamate antagonist riluzole improves outcome after acute spinal cord injury: results from the RISCIS randomised controlled trial analysed using a global statistical analytic technique. [PDF]

open access: yesEBioMedicine
Fehlings MG   +25 more
europepmc   +1 more source

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