Results 211 to 220 of about 253,651 (355)

Structural and Spectroscopic Insights into Catalytic Intermediates of a [NiFe]‐hydrogenase from Group 3

open access: yesChemBioChem, EarlyView.
Hydrogenases catalyze reversible H2 production and are potential models for renewable energy catalysts. Here, the full redox landscape of a group 3 [NiFe]‐hydrogenase from methanothermococcus thermolithotrophicus is elucidated, resembling group 1 enzymes.
Marion Jespersen   +4 more
wiley   +1 more source

Freeze-drying of live virus vaccines : a review [PDF]

open access: yes, 2015
Daoussi, R   +4 more
core   +2 more sources

The Aging Gut–Brain Axis: Effects of Dietary Polyphenols and Metal Exposure

open access: yesChronic Diseases and Translational Medicine, EarlyView.
The influence of gut microbiota on brain health ABSTRACT Diet provides essential metals, which are required for the growth, development, and well‐functioning of the body. Nonetheless, some natural and human activities add toxic heavy metals to the diet, consequently introducing them to our bodies, resulting in several disorders and death. The intestine,
Luqi Cao   +7 more
wiley   +1 more source

Crystal Structure of Sodium ni -Glutamate Dihydrate

open access: yesAnalytical Sciences, 1992
Chiaki Sano   +3 more
openaire   +3 more sources

Optimization of CEST MRI Reporter Protein Design Using Cation‐Pi Networks

open access: yesChemistry – A European Journal, EarlyView.
A novel engineering approach can produce reporter proteins for cell and viral therapy tracking with unique magnetic resonance imaging (MRI) signatures, detectable with chemical exchange saturation transfer (CEST). We discover how cation‐π interactions between amino acid groups can help us fine‐tune magnetic resonance properties for noninvasive ...
David E. Korenchan   +8 more
wiley   +1 more source

Substitution of CH3 by CH2F in 2‐Methylerythritol Cyclodiphosphate Triggers Potent Inhibition of IspG with Concomitant Fluoride Ion Expulsion

open access: yesChemistry – A European Journal, EarlyView.
The fluoromethyl analogue of MEcPP was identified as a very potent inhibitor of the oxygen‐sensitive [4Fe‐4S] metalloenzyme IspG. In the course of the IspG‐catalyzed transformation, this novel compound undergoes fluoride elimination, offering additional evidence for the involvement of a carbanionic intermediate in the mechanism of this enzyme ...
Clea Witjaksono   +7 more
wiley   +1 more source

4‐Dimethylamino‐1,8‐Naphthalimide as a Fluorescence Signal Amplification for Site Selective and in Situ Probing of the Hydroxyl Radical

open access: yesChemistry – A European Journal, EarlyView.
4‐dimethylamino‐1,8‐naphthalimide (NMI) as new fluorescence‐responsive tool for HO• detection. Proof of concept illustrating that NMI selectively probes HO• produced by Cu‐bound to Aβ16 in presence of scavengers with an amplified response. Abstract Overproduction of reactive oxygen species (ROS) is involved in several diseases.
Yelisetty Venkata Suseela   +4 more
wiley   +1 more source

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