Inhibition of Synaptosomal Uptake of 3H-L-glutamate and 3H-GABA by Hyperforin, a Major Constituent of St. John's Wort The Role of Amiloride Sensitive Sodium Conductive Pathways [PDF]
Meinolf Wonnemann
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TK2268 encodes the major aminotransferase involved in the conversion from oxaloacetic acid to aspartic acid in <i>Thermococcus kodakarensis</i>. [PDF]
Su Y+5 more
europepmc +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
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Emergent glutamate & dopamine dysfunction in VPS35<sub>(D620N)</sub> knock-in mice and rapid reversal by LRRK2 inhibition. [PDF]
Kamesh A+11 more
europepmc +1 more source
Room D, 10/17/2000 9: 00 AM - 11: 00 AM (PS) Presynaptic Calcium Channels Coupled to Glutamate Release Are Less Sensitive than Sodium Channels to Isoflurane or Propofol [PDF]
Hugh C. Hemmings+2 more
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Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza+4 more
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Neuroprotection by Mitochondrial NAD Against Glutamate-Induced Excitotoxicity. [PDF]
Paiva BS+7 more
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New insights into epileptic spasm generation and treatment from the TTX animal model
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann+2 more
wiley +1 more source
Ventral tegmental area interneurons revisited: GABA and glutamate projection neurons make local synapses. [PDF]
Oriol L+6 more
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Inhibition of glutamate release by BIA 2-093 and BIA 2-024, two novel derivatives of carbamazepine, due to blockade of sodium but not calcium channels11Abbreviations: AED, antiepileptic drug; CBZ, carbamazepine; OXC, oxcarbazepine; and 4-AP, 4-aminopyridine. [PDF]
António Francisco Ambrósio+5 more
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