Results 261 to 270 of about 239,405 (357)

Astrocyte in Neurological Disease: Pathogenesis and Therapy. [PDF]

MedComm (2020)
Huang M, Long A, Hao L, Shi Z, Zhang M.
europepmc   +1 more source

The role of the electrogenic sodium pump in the glutamate afterhyperpolarization of frog spinal cord.

, 1983
Ante L. Padjen, Peter A. Smith
openalex   +1 more source

Efficacy and tolerability of perampanel as add‐on therapy in Dravet syndrome: A prospective real‐world study

Epilepsia Open, EarlyView.
Abstract Objective To investigate the efficacy and tolerability of perampanel (PER) on Dravet syndrome in China by a prospective real‐world study. Methods We prospectively enrolled children with Dravet syndrome from the neurology clinic of Shenzhen Children's Hospital from September 2020 to October 2021.
Han Wang, Hong Chen, Xin Ding, Xueyan Cao, Jiahui Mai, Huafang Zou, Dongfang Zou, Yanwei Zhu, Jianxiang Liao, Dezhi Cao   +9 more
wiley   +1 more source

The Involvement of the Endocannabinoid, Glutamatergic, and GABAergic Systems in PTSD. [PDF]

Int J Mol Sci
Grzesińska AD.
europepmc   +1 more source

Time-quality tracking of monosodium glutamate, sodium saccharin, and a citric acid-saccharin mixture

, 1991
Sharon A. Zwillinger, Bruce P. Halpern
openalex   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Sodium Reduction Through Sensory Interactions With NaCl: Strategies and Underlying Mechanisms. [PDF]

Food Sci Nutr
Li X, Shi B, Chen R, Li H, Zhang L, Zhao L.   +5 more
europepmc   +1 more source

Real‐world use of adjunctive perampanel for focal‐onset seizures in Italy: A mirroring clinical practice study of perampanel in adults and adolescents (AMPA)

Epilepsia Open, EarlyView.
Abstract Objective The AMPA study (Study 501; NCT04257604) was a multicenter, prospective, 12‐month observational study in Italy that evaluated the effectiveness and safety of adjunctive perampanel in patients with focal‐onset seizures (FOS), with or without focal to bilateral tonic–clonic seizures (FBTCS).
Alfredo D'Aniello, Anna Teresa Giallonardo, Paolo Tinuper, Oriano Mecarelli, Umberto Aguglia, Giovanni Assenza, Antonio Gambardella, Maria Paola Canevini, Renato Scifo, Stefano Meletti, Valentina De Giorgis, Enrica Bonanni, Roberto Michelucci, Caterina Cerminara, Antonino Romeo, Federico Vigevano, Francesca Felicia Operto, Luciana Tramacere, Giancarlo Di Gennaro, Alfonso Iudice on behalf of the AMPA Study group, Leock Y. Ngo, Anna Patten, Anna Lisa Gentile, Andrea Pecori, Samantha Goldman   +24 more
wiley   +1 more source

Role of Glutamate Excitotoxicity in Glioblastoma Growth and Its Implications in Treatment. [PDF]

Cell Biol Int
Moriarty C, Gupta N, Bhattacharya D.
europepmc   +1 more source

Perampanel as a second‐line therapy to midazolam reduces soman‐induced status epilepticus and neurodegeneration in rats

Epilepsia Open, EarlyView.
Abstract Objective A benzodiazepine (diazepam or midazolam) is one of the current standards of care therapies to effectively terminate organophosphorus nerve agent‐induced status epilepticus when administered shortly after onset. Preclinical studies showed that benzodiazepines were less effective in stopping status epilepticus when treatment was ...
Hailey G. Steier, Caroline R. Schultz, Jerome Niquet, Donna A. Nguyen, Michael F. Stone, Abiel K. Biney, Marcio de Araujo Furtado, Claude G. Wasterlain, Lucille A. Lumley   +8 more
wiley   +1 more source