Results 261 to 270 of about 235,457 (380)

Inherited metabolic epilepsies–established diseases, new approaches

open access: yesEpilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Emergent glutamate & dopamine dysfunction in VPS35<sub>(D620N)</sub> knock-in mice and rapid reversal by LRRK2 inhibition. [PDF]

open access: yesNPJ Parkinsons Dis
Kamesh A   +11 more
europepmc   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

open access: yesEpilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza   +4 more
wiley   +1 more source

Neuroprotection by Mitochondrial NAD Against Glutamate-Induced Excitotoxicity. [PDF]

open access: yesCells
Paiva BS   +7 more
europepmc   +1 more source

New insights into epileptic spasm generation and treatment from the TTX animal model

open access: yesEpilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann   +2 more
wiley   +1 more source

Ventral tegmental area interneurons revisited: GABA and glutamate projection neurons make local synapses. [PDF]

open access: yesElife
Oriol L   +6 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy