Results 271 to 280 of about 235,457 (380)

Engineered Exosome‐Based Senolytic Therapy Alleviates Stroke by Targeting p21+CD86+ Microglia

Exploration, EarlyView.
We identified a harmful immune cell type, p21+CD86+ microglia, driving post‐stroke inflammation and developed a targeted exosome‐based therapy (Que@micro‐Exo) to eliminate these cells. This innovative treatment reduced inflammation, alleviated brain damage, and improved recovery in stroke models, offering a promising strategy for stroke and other ...
Jialei Yang, Shipo Wu, Miao He
wiley   +1 more source

GPRC6A as a novel kokumi receptor responsible for enhanced taste preferences by ornithine. [PDF]

Elife
Yamamoto T, Ueji K, Mizuta H, Inui-Yamamoto C, Kumamoto N, Shibata Y, Ugawa S.   +6 more
europepmc   +1 more source

Exploring the Neuroprotective Role of Selenium: Implications and Perspectives for Central Nervous System Disorders

Exploration, EarlyView.
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang, Ying Liu, Xiadong Zhu, Lizhen He, Tianfeng Chen   +4 more
wiley   +1 more source

Studies on the fermentation- inhibiting substances contained in the waste liquor of the sodium glutamate industry Part 2

, 1952
Toshi Fukai, Seishichi Iwashita, Seiichiro Iyano   +2 more
openalex   +2 more sources

Glutathione Metabolism of the Brain-The Role of Astrocytes. [PDF]

J Neurochem
Dringen R, Arend C.
europepmc   +1 more source

Amino Acid Complexation Fractionates Nickel Isotopes: Implications for Tracing Nickel Cycling in the Environment. [PDF]

Environ Sci Technol Lett
Selden CR, Schilling K, Basu A, Timm J, Saunders N, Yee N.   +5 more
europepmc   +1 more source

Freeze-drying of live virus vaccines : a review [PDF]

, 2015
Daoussi, R, De Beer, Thomas, Hansen, Laurent, Remon, Jean Paul, Vervaet, Chris   +4 more
core   +2 more sources

Self‐Emulsifying Biocatalysis Based on an Amphipathic Protein BslA‐Modified Esterase Functioning as a Fine‐Tuned System for Oil Hydrolysis

Food Bioengineering, EarlyView.
BslA is a promising tool to create an robust self‐emulsifying biocatalysis platform by reducing the droplet sizes of emulsion and improving its stability. It could guarantee the efficient hydrolysis of astaxanthin esters catalyzed by Est3‐14 without extra emusifier, increasing the yield of free astaxanthin to 184 μg·mL−1.
Xiaoxuan Yao, Kunpeng Gao, Hao Dong, Qian Sun, Jingyuan Liu, Yang Hu, Jianan Sun, Xiangzhao Mao   +7 more
wiley   +1 more source

Structural basis of excitatory amino acid transporter 3 substrate recognition. [PDF]

Proc Natl Acad Sci U S A
Qiu B, Boudker O.
europepmc   +1 more source

Prophylactic Effects of Astragalus Polysaccharides on Depression‐Like Behaviors in Rats With Chronic Unpredictable Mild Stress: A Role of Gut‐Microbiota–Brain Axis

Food Frontiers, EarlyView.
This study complements the pathogenesis of depression, and the effects of APS from the perspective of “gut microbiome ‐ immunity ‐ metabolome” axis. This study also provides a novel research strategy and approaches for demonstrating the anti‐depression effects of plant polysaccharides, and lays a solid foundation for discovering new medicines from ...
Xiaojie Liu, Wenlu Xu, Ziyu Zhao, Xiaoling Wu, Senyan Wang, Chen Jian, Mengyu Li, Ke Li, Yulan Wang, Xuemei Qin   +9 more
wiley   +1 more source