Results 281 to 290 of about 235,457 (380)

Channels and Transporters in Ischemic Brain Edema. [PDF]

open access: yesJ Inflamm Res
Yu J   +9 more
europepmc   +1 more source

Subtle Alterations in Hippocampal Neuronal Activity Coincide With Early Sex‐Specific Differences in Amyloidosis and Microglia in a Pre‐Symptomatic Mouse Model of Alzheimer‐Like Pathology

open access: yesGlia, EarlyView.
In a pre‐symptomatic mouse model of Alzheimer disease, despite higher amyloid‐β load, females display fewer plaques than males. More efficient synaptic transmission as well as less microgliosis point to better early coping with pathogenesis in females.
Thomas Chaigneau   +7 more
wiley   +1 more source

Effect of N-Acetylcysteine in Mitochondrial Function, Redox Signaling, and Sirtuin 3 Levels in the Heart During Cardiorenal Syndrome Type 4 Development. [PDF]

open access: yesAntioxidants (Basel)
Amador-Martínez I   +15 more
europepmc   +1 more source

Leveraging core enzyme structures for microbiota targeted functional regulation: Urease as an example

open access: yesiMeta, EarlyView.
We present an innovative methodology that integrates core enzyme identification, protein structural characterization, regulator virtual screening, and functional validation to achieve precise microbiome functional regulation. As a proof of concept, we focused on the regulation of urea decomposition by the rumen microbiota in ruminants. This methodology
Shengguo Zhao   +9 more
wiley   +1 more source

Myocardial metabolic flexibility following ketone infusion demonstrated by hyperpolarized [2-13C]pyruvate MRS in pigs. [PDF]

open access: yesSci Rep
Bech SK   +6 more
europepmc   +1 more source

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