Results 301 to 310 of about 235,457 (380)

Ameliorative effect of vitamin C and melatonin on the pancreatic toxicity induced by sodium glutamate in adult male albino rat: histological and immunohistochemical study

A. Mahmoud, Abdel Hamid Sayed Abo Bakr Ali, Medhat Atta, Sayed Ali   +3 more
openalex   +1 more source

Uncertainty Quantification Using Ensemble Learning and Monte Carlo Sampling for Performance Prediction and Monitoring in Cell Culture Processes

Journal of Raman Spectroscopy, EarlyView.
This study introduces a novel method for uncertainty quantification in machine learning models for cell culture processes, addressing challenges of limited training data. By combining ensemble learning and Monte Carlo simulations, the approach enhances model robustness, as demonstrated in predicting antibody concentrations and real‐time monitoring of ...
Thanh Tung Khuat, Robert Bassett, Ellen Otte, Bogdan Gabrys   +3 more
wiley   +1 more source

THE EFFECT OF PROLONGED ADMINISTRATION OF SODIUM GLUTAMATE ON CERTAIN INDICATORS OF LIPID METABOLISM AND DEVELOPMENT OF OBESITY IN RATS

V. V. Bevzo
openalex   +2 more sources

Polypept(o)ide‐Based Core–Shell Bottlebrush Polymers: A Versatile Platform for Drug Encapsulation

Macromolecular Bioscience, EarlyView.
This study developed polypept(o)ide‐based core–shell brushes (CSBs) with tunable sizes (Rh: 17–70 nm) for hydrophobic drug delivery. CSBs achieved 10% dasatinib loading through π–π interactions, enabling sustained release over 72 h. Notably, CSB‐dasatinib complexes showed comparable cell viability reduction to the free drug in U‐87 MG cells ...
Bonan Zhao, Jingyuan Wei, Rüdiger Berger, Lin Jian, Kaloian Koynov, Heyang Zhang, Matthias Barz   +6 more
wiley   +1 more source

A retropepsin-like bacterial protease regulates ribosome modification and polypeptide production. [PDF]

J Biol Chem
Little RH, Chandra G, Saalbach G, Martins C, Thompson CMA, Malone JG.   +5 more
europepmc   +1 more source

Hybrid Polymers Bearing Mono/Oligo‐L‐Lysine(Z)s: ADMET Polymerization and Structural Investigations in the Solid State

Macromolecular Chemistry and Physics, EarlyView.
The structure formation of hybrid‐polymers is investigated via IR‐spectroscopy, based on embedded lysine (Lys) oligomers inside a polyolefine‐chain. Synthesis is accomplished via ADMET polymerization generating the hybrid polymers: Lysn = 1, A‐[Lysn = 1]m = 18, (A‐[Lysn = 12]m = 8, A‐[Lysn = 24]m = 4) and their pre‐polymers (Lysn = 12, Lysn = 24).
Merve Basak Canalp, Wolfgang H. Binder
wiley   +1 more source

Fluoride Exposure Increases the Activity of the Cystine/Glutamate Exchanger in Glia Cells. [PDF]

Neurochem Res
Ocharán-Mercado A, Loaeza-Loaeza J, Hernández-Sotelo D, Cid L, Hernández-Kelly LC, Felder-Shmittbuhl MP, Ortega A.   +6 more
europepmc   +1 more source

Comparative Analysis of Two Elastic Types of Surface‐Crosslinked Gelatin Nanoparticles as Suitable Systems for Macromolecular Drug Delivery

Macromolecular Chemistry and Physics, EarlyView.
This study provides a development of surface‐crosslinked gelatin nanoparticles and explores their potential for the delivery of macromolecular drugs. The two nanoparticulate systems, consisting of either gelatin type A or B, display significantly different physicochemical and mechanical properties, with the latter evaluated by atomic force microscopy ...
Armin W. Novak, Stefan V. Pochmann, Alexander Horn, Agnes‐Valencia Weiss, Marc Schneider   +4 more
wiley   +1 more source

Deletion of <i>Re</i>-citrate synthase allows for analysis of contributions of tricarboxylic acid cycle directionality to the growth of <i>Heliomicrobium modesticaldum</i>. [PDF]

Appl Environ Microbiol
Layton AM, McCauley C, Redding KE.
europepmc   +1 more source

Mapping protein–protein interactions by mass spectrometry

Mass Spectrometry Reviews, EarlyView.
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu, Lawrence Abad, Lopamudra Chatterjee, Ileana M. Cristea, Markku Varjosalo   +4 more
wiley   +1 more source