Results 311 to 320 of about 235,457 (380)

Plasma Metabolic Profiles of Chronic and Recurrent Uveitis Treated by Artesunate in Lewis Rats. [PDF]

Biomedicines
Gong X, Fan J, Huang H, Xu F, Hu K, Liu J, Tan Y, Chen F.   +7 more
europepmc   +1 more source

Evidence of Involvement of the Calcitonin Gene‐Related Peptide in Restless Legs Syndrome

Movement Disorders, EarlyView.
Abstract Background Restless legs syndrome (RLS) is a common sensory‐motor disorder characterized by an urge to move the legs, often with unpleasant sensations, particularly during rest. Current treatments include iron supplementation, dopamine agonists, and opioids, but new therapeutic approaches are needed.
Maria P. Mogavero, Mojibola Fowowe, Akeem Sanni, Mona Goli, Giuseppe Lanza, Francesca L'Episcopo, Luigi Ferini‐Strambi, Yehia Mechref, Raffaele Ferri   +8 more
wiley   +1 more source

Mitochondrial dysfunction drives a neuronal exhaustion phenotype in methylmalonic aciduria. [PDF]

Commun Biol
Denley MCS, Straub MS, Marcionelli G, Güra MA, Penton D, Delvendahl I, Poms M, Vekeriotaite B, Cherkaoui S, Conte F, von Meyenn F, Froese DS, Baumgartner MR.   +12 more
europepmc   +1 more source

The role of astrocyte metabolic reprogramming in ischemic stroke (Review). [PDF]

Int J Mol Med
Chen W, Mao T, Ma R, Xiong Y, Han R, Wang L.   +5 more
europepmc   +1 more source

The Quinoline Photoremovable Group (PPG) Platform—A Medicinal Chemist's Approach for Photocage Development and Applications

Medicinal Research Reviews, EarlyView.
ABSTRACT Photoremovable protecting groups (PPGs) offer a straightforward solution for the temporary inactivation of biologically active substrates and their subsequent controlled release by light irradiation. Their relatively easy design and mode of application have made them useful tools for studying dynamic biological processes in vitro and in vivo ...
Bence Kontra, Zoltán Mucsi, Janez Ilaš, Petra Dunkel   +3 more
wiley   +1 more source

Repurposing Antiepileptic Drugs for Cancer: A Promising Therapeutic Strategy. [PDF]

J Clin Med
Tarawneh N, Hussein SA, Abdalla S.
europepmc   +1 more source

Comparison of Low‐Gluten Diets Rich in Oats or Rice—A 6‐Week Randomized Clinical Trial With Metabolically Challenged Volunteers

Molecular Nutrition &Food Research, EarlyView.
The aim of this study is to compare oats and rice as the main cereal source of a low‐gluten diet followed by metabolically challenged volunteers. The participants consumed four portions of either oat or rice products daily for 6 weeks and avoided glutinous cereals.
Enni Mannila, Petrus Nuotio, Anni Kuosmanen, Suchetana De Storvik, Anna Kårlund, Aija Jukkara, Milla‐Maria Tauriainen, Johanna Närväinen, Marjukka Kolehmainen, Kaisa M. Linderborg   +9 more
wiley   +1 more source

A pathway toward clinical translation of hyperpolarized [1,4‐13C2,2,3‐d2]fumarate as an imaging biomarker for early cellular necrosis in vivo

Magnetic Resonance in Medicine, EarlyView.
Abstract Purpose The detection of hyperpolarized carbon‐13 (HP 13C)‐fumarate conversion to 13C‐malate using 13C‐MRSI is a biomarker for early detection of cellular necrosis. Here, we describe the translation of HP 13C‐fumarate as a novel human imaging agent, including the evaluation of biocompatibility and scaling up of the hyperpolarization methods ...
Jonathan R. Birchall, Pascal Wodtke, Ashley Grimmer, Esben S. S. Hansen, Lotte B. Bertelsen, Nikolaj Bøgh, Marta Wylot, Maria J. Zamora‐Morales, Otso Arponen, Ines Horvat‐Menih, Elizabeth C. Latimer, Fung Tan, Evita Pappa, Johann Graggaber, Joseph Cheriyan, Kelly Holmes, Matthew J. Locke, Helen Sladen, Joan Boren, Mikko I. Kettunen, Anita Chhabra, Ian B. Wilkinson, Christoffer Laustsen, Kevin Brindle, Mary A. McLean, Ferdia A. Gallagher   +25 more
wiley   +1 more source

Efficacy of Plasmalogens on Monosodium Glutamate-Induced Neurotoxicity in Male Rats Through NF-<i>κ</i>B and p38 MAPK Signaling Pathways. [PDF]

Oxid Med Cell Longev
Abdou HM, Hamaad FA, Elmageed GMA, Katano H, Ghoneum MH.   +4 more
europepmc   +1 more source

Dynamics of Ionic and Cytotoxic Edema During Acute and Subacute Stages of Patients With Ischemic Stroke: Complementarity of ²³Na MRI and Diffusion MRI. [PDF]

NMR Biomed
Cotinat M, Messaoudi N, Robinet E, Suissa L, Doche E, Guye M, Audoin B, Bensoussan L, Ranjeva JP, Zaaraoui W.   +9 more
europepmc   +1 more source