Results 101 to 110 of about 1,302,710 (185)

Role of hyaluronate containing artificial tears in mitigating markers of dry eye disease using in vitro models

Indian Journal of Ophthalmology
Purpose: Ocular surface discomfort and dry eye disease (DED) are the most common conditions addressed by ophthalmologists worldwide. Artificial tear substitutes are used as the first line of treatment management for DED patients.
Sharel P Karkada, Sheril P Karkada, Anushree Bhatkal, Srihari Balaraj, Ritica Mukherji, Arkasubhra Ghosh, Pooja Khamar, Nimisha R Kumar   +7 more
doaj   +1 more source

Hybrid formulations of liposomes and bioadhesive polymers improve the hypotensive effect of the melatonin analogue 5-MCA-NAT in rabbit eyes.

PLoS ONE, 2014
For the treatment of chronic ocular diseases such as glaucoma, continuous instillations of eye drops are needed. However, frequent administrations of hypotensive topical formulations can produce adverse ocular surface effects due to the active substance ...
Daniela Quinteros, Marta Vicario-de-la-Torre, Vanessa Andrés-Guerrero, Santiago Palma, Daniel Allemandi, Rocío Herrero-Vanrell, Irene T Molina-Martínez   +6 more
doaj   +1 more source

Topical rebamipide improves lid wiper epitheliopathy

Clinical Ophthalmology, 2013
Hirotaka Itakura,1,2 Tomoyuki Kashima,2 Mariko Itakura,1 Hideo Akiyama,2 Shoji Kishi2 1Department of Ophthalmology, Maebashi Red Cross Hospital, 2Department of Ophthalmology, Gunma University, School of Medicine, Maebashi, Japan Abstract: Administration ...
Itakura H, Kashima T, Itakura M, Akiyama H, Kishi S   +4 more
doaj  

Comparison of novel lipid-based eye drops with aqueous eye drops for dry eye: a multicenter, randomized controlled trial

, 2015
Peter A Simmons, Cindy Carlisle-Wilcox, Joseph G Vehige Ophthalmology Research and Development, Allergan, Inc., Irvine, CA, USA Background: Dry eye may be caused or exacerbated by deficient lipid secretion.
Simmons PA, Carlisle-Wilcox C, Vehige JG
core  

A two-Week, randomized, double-masked study to evaluate safety and efficacy of lubricin (150 μg/mL) eye drops versus sodium hyaluronate (HA) 0.18% eye drops (Vismed®) in patients with moderate dry eye disease

, 2017
Purpose: The objective of this clinical trial (NCT02507934) was to assess the efficacy and safety of recombinant human lubricin as compared to a 0.18% sodium hyaluronate (HA) eye drop in subjects with moderate dry eye disease (DED). Methods: DEWS Grade 2-
Sullivan, Benjamin D., Schmidt, Tannin A., BRUSCOLINI, ALICE, SACCHETTI, MARTA, Truitt, Edward R., Mantelli, Flavio, LAMBIASE, ALESSANDRO, Sullivan, David A., Jay, Gregory D.   +8 more
core   +1 more source

Mucoadhesion of pharmaceutical solutions containing sodium hyaluronate - influence of sodium hyaluronate concentration and molecular weight

, 2023
Otopine natrijeva hijaluronata koriste se kao umjetne suze koje vlaže i regeneriraju oko. Natrijev hijaluronat kao polimer sastavljen od ponavljajućih jedinica disaharida D-glukuronske kiseline i N-acetil-Dglukozamina pokazuje i mukoadhezivno svojstvo,
Strbad, Klara
core   +1 more source

Effectiveness of sodium hyaluronate eyedrops in the treatment of dry eye

, 2006
BACKGROUND: Dry eye is a common condition, affecting approximately 10-20% of the adult population. Artificial tears are often effective in relieving symptoms in mild and moderate dry eye by replenishing deficient tear volume.
Murphy, Paul James, Johnson, M. E., Boulton, Michael Edwin   +2 more
core   +1 more source

Development of a novel eye drop aid and evaluation of its efficacy.

PLoS ONE
PurposeThe aim of this study was to develop a new eye drop aid and investigate its efficacy in glaucoma patients.MethodsThe developed eye drop aid is compatible with most therapeutic eye drops and helps users with limited neck retroversion.
Yuka Kasai, Masako Sakamoto, Yuji Matsuda, Yuka Ito, Hirotaka Haro, Kenji Kashiwagi   +5 more
doaj   +1 more source

The Effect of Periocular Fatty Acids and 0.15% Hyaluronate Eye Drops Application on Keratoconjunctivitis Sicca in Dogs: An Exploratory Study

, 2019
The aim of this exploratory study was to evaluate the efficacy of a periophthalmic cream of a pool of fatty acids (FAG®) in association with 0.15% hyaluronate eye drops in alleviating the clinical symptoms of keratoconjunctivitis sicca (KCS) in a case ...
Nieddu, Annalisa, Pasolini, Maria Pia, Fiorentin, Pier Giorgio, Della Valle, Giovanni, Lamagna, Barbara, AMALFITANO, CLAUDIA, Lamagna, Francesco   +6 more
core   +1 more source

Sodium hyaluronate eye drops in the treatment of dry eye disease: an open label, uncontrolled, multi-centre trial.

Journal of Ayub Medical College, Abbottabad : JAMC, 2014
Dry eye disease (DED) is one of the most frequently encountered ocular morbidities. The objective of this study was to assess the performance of sodium hyaluronate eye drop for eight weeks in patients with DED.This was a multi-centre, open-label, uncontrolled clinical trial carried out at different centres of Pakistan, from August 2009 to November 2010.
Alyscia, Cheema, Tariq, Aziz, Sajid Ali, Mirza, Ahson, Siddiqi, Neeta, Maheshwary, Muhammad Athar, Khan   +5 more
openaire   +1 more source