Results 101 to 110 of about 22,958 (276)

Cardiosphere-derived cells demonstrate metabolic flexibility that Is influenced by adhesion status [PDF]

, 2017
Adult stem cells demonstrate metabolic flexibility that is regulated by cell adhesion status. The authors demonstrate that adherent cells primarily utilize glycolysis, whereas suspended cells rely on oxidative phosphorylation for their ATP needs.
Abraham, M. Roselle, Afzal, Junaid, Aon, Miguel A, Chan, Angel, Foster, D. Brian, Guan, Yufan, Karakas, Mehmet Fatih, O\u27Rourke, Brian, Pomper, Martin, Rathmell, Jeffrey, Tsui, Benjamin, Vakrou, Styliani, Wahl, Richard, Woldemichael, Kirubel   +13 more
core   +2 more sources

Reporter gene-engineering of human induced pluripotent stem cells during differentiation renders in vivo traceable hepatocyte-like cells accessible

Stem Cell Research, 2019
Primary hepatocyte transplantation (HTx) is a safe cell therapy for patients with liver disease, but wider application is circumvented by poor cell engraftment due to limitations in hepatocyte quality and transplantation strategies. Hepatocyte-like cells
Candice Ashmore-Harris, Samuel JI Blackford, Benjamin Grimsdell, Ewelina Kurtys, Marlies C Glatz, Tamir S Rashid, Gilbert O Fruhwirth   +6 more
doaj  

Conserved charged amino acid residues in the extracellular region of sodium/iodide symporter are critical for iodide transport activity

Journal of Biomedical Science, 2010
Background Sodium/iodide symporter (NIS) mediates the active transport and accumulation of iodide from the blood into the thyroid gland. His-226 located in the extracellular region of NIS has been demonstrated to be critical for iodide transport in our ...
Liang Ji-An, Wu Shih-Lu, Kao Chia-Hung, Ho Tin-Yun, Li Chia-Cheng, Hsiang Chien-Yun   +5 more
doaj   +1 more source

Size Increment During Surveillance in Papillary Thyroid Cancer: Evidence Synthesis and Dose–Response Meta‐Analysis

Cancer Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Introduction Differentiated thyroid cancer has become a prevalent malignant tumor, particularly papillary thyroid carcinoma (PTC), constituting over 90% of cases. Most PTC lesions are asymptomatic and remain subclinical throughout life, and active surveillance is now being used to monitor the progression of these lesions and intervene when ...
Mohamed Badie Ahmed, Emad Naem, Harman Saman, Abeer Alsherawi, Asma Syed, Noora Al‐Abdulla, Latifa Alkaabi, Mahmoud A. Zirie, Suhail A. Doi   +8 more
wiley   +1 more source

Hashimoto's thyroiditis and autoimmune gastritis [PDF]

, 2017
The term "thyrogastric syndrome" defines the association between autoimmune thyroid disease and chronic autoimmune gastritis (CAG), and it was first described in the early 1960s.
Brusca, Nunzia, Capriello, Silvia, Cellini, Miriam, Centanni, Marco, Gargano, Lucilla, Santaguida, MARIA GIULIA, Virili, Camilla   +6 more
core   +3 more sources

Update of the Scientific Opinion on the risks for human health related to the presence of perchlorate in food

EFSA Journal, Volume 23, Issue 5, May 2025.
Abstract The European Commission asked EFSA to update its 2014 risk assessment on perchlorate in food. Perchlorate is a contaminant of both natural and anthropogenic sources present in food and drinking water. It is a substrate for the sodium iodide symporter (NIS) and competitively inhibits the uptake of iodide into the thyroid.
EFSA Panel on Contaminants in the Food Chain (CONTAM), Helle Katrine Knutsen, Agneta Åkesson, Vasileios Bampidis, Margherita Bignami, Laurent Bodin, Gisela Degen, Antonio Hernández‐Jerez, Tim Hofer, Christer Hogstrand, Stefano Landi, Jean‐Charles Leblanc, Kyriaki Machera, Evangelia Ntzani, Guido Rychen, Salomon Sand, Katharina Vejdovszky, Barbara Viviani, Aleksandra Buha Djordjevic, Thorhallur Halldorsson, Chantra Eskes, Olaf Mosbach‐Schulz, Francesca Riolo, Elena Rovesti, Efisio Solazzo, Alexios Zormpas, Tuuli Tauriainen, James Kevin Chipman   +27 more
wiley   +1 more source

Translational Research Using Sodium/Iodide Symporter

Journal of Korean Endocrine Society, 2006
184 1915년에 갑상선 조직에 요오드가 선택적으로 축적된다 는 사실이 밝혀졌고, 그 이후 갑상선 질환의 진단과 치료에 방사성요오드가 널리 이용되게 되었다. 갑상선 조직은 요오 드를 혈액에서부터 20~40배 정도 높은 농도로 축적한다. 약 60년 전부터 방사성요오드를 갑상선 기능을 측정하는 추적 자로 사용하였고, 곧이어 갑상선기능항진증과 갑상선암에서 I-131를 치료제로 사용하게 되었다. 그러나 갑상선 세포에 요오드가 선택적으로 섭취되는 기 전은 최근에야 밝혀졌다.
Joo Hyun Kang, June-Key Chung
openaire   +2 more sources

A Concise Atlas of Thyroid Cancer Next-Generation Sequencing Panel ThyroSeq v.2 [PDF]

, 2017
The next-generation sequencing technology allows high out-put genomic analysis. An innovative assay in thyroid cancer, ThyroSeq® was developed for targeted mutation detection by next generation sequencing technology in fine needle aspiration and tissue ...
Alsina, Jorge, Alsina, Raul, Gulec, Seza
core   +2 more sources

Peer review of the pesticide risk assessment for the active substance etoxazole in light of confirmatory data on the endocrine disruption assessment

EFSA Journal, Volume 23, Issue 4, April 2025.
Abstract The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessment carried out by the competent authority of the rapporteur Member State Greece for the pesticide active substance etoxazole are reported.
European Food Safety Authority (EFSA), Fernando Álvarez, Maria Arena, Domenica Auteri, Sofia Batista Leite, Marco Binaglia, Anna Federica Castoldi, Arianna Chiusolo, Angelo Colagiorgi, Mathilde Colas, Federica Crivellente, Chloe De Lentdecker, Isabella De Magistris, Franco Ferilli, German Giner Santonja, Katrin Halling, Alessio Ippolito, Frederique Istace, Dimitra Kardassi, Aude Kienzler, Anna Lanzoni, Alberto Linguadoca, Jochem Louisse, Iris Mangas, Tunde Molnar, Martina Panzarea, Juan Manuel Parra Morte, Alexandra Piti, Simone Rizzuto, Rachel Sharp, Csaba Szentes, Manuela Tiramani, Giorgia Vianello, Laura Villamar‐Bouza   +33 more
wiley   +1 more source

Accomplishments and challenges in stem cell imaging in vivo. [PDF]

, 2019
Stem cell therapies have demonstrated promising preclinical results, but very few applications have reached the clinic owing to safety and efficacy concerns.
Bose, Rajendran JC, Mattrey, Robert F
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