Results 141 to 150 of about 22,958 (276)

Application of Probabilistic Risk Assessment in Establishing Perchlorate and Goitrogen Risk Mitigation Strategies. [PDF]

, 2015
This paper applies probabilistic risk assessment in quantifying risks from cumulative and aggregate risk pathways for selected goitrogens in water and food.
Crawford-Brown, Douglas
core   +3 more sources

A Novel Chimeric Poxvirus Encoding hNIS Is Tumor-Tropic, Imageable, and Synergistic with Radioiodine to Sustain Colon Cancer Regression

Molecular Therapy: Oncolytics, 2019
Colon cancer has a high rate of recurrence even with good response to modern therapies. Novel curative adjuncts are needed. Oncolytic viral therapy has shown preclinical promise against colon cancer but lacks robust efficacy in clinical trials and raises
Susanne G. Warner, Sang-In Kim, Shyambabu Chaurasiya, Michael P. O’Leary, Jianming Lu, Venkatesh Sivanandam, Yanghee Woo, Nanhai G. Chen, Yuman Fong   +8 more
doaj  

Decreased Expression of Thyroglobulin and Sodium Iodide Symporter Genes in Hashimoto’s Thyroiditis

International Journal of Endocrinology, 2014
Aim. The aim of the study was to compare the expression of sodium iodide symporter (NIS), thyroglobulin (Tg), tumor necrosis factor-α (TNFα), and interleukin-1β genes in patients with Hashimoto’s thyroiditis (HT) and healthy individuals.
Anna Popławska-Kita, Beata Telejko, Katarzyna Siewko, Maria Kościuszko-Zdrodowska, Natalia Wawrusewicz-Kurylonek, Adam Krętowski, Justyna Hryniewicka, Janusz Dzięcioł, Witold Bauer, Robert Milewski, Małgorzata Szelachowska, Maria Górska   +11 more
doaj   +1 more source

Abstracts

Molecular Oncology, Volume 19, Issue S1, Page 1-895, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Targeting novel sodium iodide symporter interactors ADP-ribosylation factor 4 (ARF4) and valosin-containing protein (VCP) enhances radioiodine uptake.

Cancer Research, 2019
The sodium iodide symporter (NIS) is required for iodide uptake which facilitates thyroid hormone biosynthesis. NIS has been exploited for over 75 years in ablative radioiodine (RAI) treatment of thyroid cancer where its ability to transport ...
A. Fletcher, Martin L Read, C. Thornton, D. Larner, V. Poole, Katie Brookes, H. Nieto, Mohammed Alshahrani, Rebecca J. Thompson, I. Landa, J. Fagin, M. Campbell, K. Boelaert, A. Turnell, V. Smith, C. McCabe   +15 more
semanticscholar   +1 more source

Low dose radiation regulates BRAF-induced thyroid cellular dysfunction and transformation [PDF]

, 2019
Background: The existence of differentiated thyroid cells is critical to respond radioactive iodide treatment strategy in thyroid cancer, and loss of the differentiated phenotype is a trademark of iodide-refractive thyroid disease.
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Sodium Iodide Symporter PET and BLI Noninvasively Reveal Mesoangioblast Survival in Dystrophic Mice

Stem Cell Reports, 2015
Muscular dystrophies are a heterogeneous group of myopathies, characterized by muscle weakness and degeneration, without curative treatment. Mesoangioblasts (MABs) have been proposed as a potential regenerative therapy.
Bryan Holvoet, Mattia Quattrocelli, Sarah Belderbos, Lore Pollaris, Esther Wolfs, Olivier Gheysens, Rik Gijsbers, Jeroen Vanoirbeek, Catherine M. Verfaillie, Maurilio Sampaolesi, Christophe M. Deroose   +10 more
doaj   +1 more source

Follicular Thyroglobulin Suppresses Iodide Uptake by Suppressing Expression of the Sodium/Iodide Symporter Gene [PDF]

, 1999
K. Suzuki
openalex   +1 more source

A Bio-inspired Learning and Classification Method for Subcellular Localization of a Plasma Membrane Protein [PDF]

, 2012
International audienceHigh-content cellular imaging is an emerging technology for studying many biological phenomena. statistical analyses on large populations (more than thousands) of cells are required. Hence classifying cells by experts is a very time-
Barlaud, Michel, Bel Haj Ali, Wafa, Crescence, Lydie, Darcourt, Jacques, Ferhat, Oumelkheir, Giampaglia, Dario, Piro, Paolo, Pourcher, Thierry   +7 more
core   +1 more source

Recurrent differentiated thyroid cancer: Towards personalized treatment based on evaluation of tumor characteristics with PET (THYROPET Study): Study protocol of a multicenter observational cohort study [PDF]

, 2014
Background: After initial treatment of differentiated thyroid carcinoma (DTC) patients are followed with thyroglobulin (Tg) measurements to detect recurrences.
Adam, J.A. (Judit), Al Younis, I. (Imad), Broek, M.R.J. ten, Brouwers, A.H. (A.), Bruin, W.I. (W.) de, De Boer, J.P. (Jan Paul), Dijk, A.B. (A.) van, Gotthardt, M. (Martin), Hoekstra, C.J. (Corneline), Hoekstra, O.S. (Otto), Huisman, M.C. (Marc), Huysmans, D., Jager, P.L. (Philip) de, Kam, B.L. (Boen), Keizer, B. (Bart) de, Kist, M. (Manfred), Klerk, J.M.H. (J. M H) de, Lavalaye, J. (J.), Lentjes, E.G.W.M. (Eef), Morreau, H. (Hans), Phan, H.T.T. (H. T T), Schelfhout, L.J., Sivro, S. (Senail), Sloof, G.W. (Gerrit), Smit, F. (F.), Smit, J.W.A. (Jan), Stokkel, M. (Marcel), Tinteren, H. (Harm) van, Vlies, M. (M.) van der, Vogel, W.V. (Wouter), Wagenaar, N.R.L. (N. R L), Zant, F.M. (F.) van der   +31 more
core   +1 more source