Results 181 to 190 of about 5,659 (220)

Expression of the Sodium/Iodide Symporter in Human Prostate Adenocarcinoma

Urology, 2010
To analyze expression of the sodium/iodide symporter (NIS) in tissue specimen from a large series of patients with prostate adenocarcinoma. Few data are available on the NIS expression in prostate tumor tissues.NIS protein expression was examined by immunohistochemistry in 78 tumor tissue specimen and their non-neoplastic counterparts.
M. Navarra, MICALI, Salvatore, SM lepore, AM Cesinaro, M. Celano, MC Sighinolfi, C. De Gaetani, S. Filetti, BIANCHI, Giampaolo, D. Russo   +9 more
openaire   +3 more sources

Molecular nuclear medicine using sodium/iodide symporter

International Congress Series, 2004
Abstract Iodide uptake occurs across the membrane of thyroid cells via an active transporter, sodium/iodide symporter (NIS). Decreased NIS expression levels account for the reduced iodide uptake in thyroid carcinomas. We found that thyroid cancer patients with positive immunostaining for NIS responded to I-131 therapy better than did the patients ...
openaire   +1 more source

Sodium Iodide Symporter and Pendrin Expression in Human Thyroid Tissues

Thyroid, 2001
Thyroid cells synthesize thyroid hormones through a multistep process during which iodide is transported through the basolateral and the apical membranes of thyrocytes. Two genes that participate in these transports and the corresponding proteins, namely sodium iodide symporter (NIS) and pendrin, the product of the Pendred syndrome gene, have recently ...
MIAN, CATERINA, LACROIX L, ALZIEU L, NOCERA M, TALBOT M, BIDART JM, SCHLUMBERGER M, CAILLOU B.   +7 more
openaire   +3 more sources

Cloning of the Human Sodium Iodide Symporter

Biochemical and Biophysical Research Communications, 1996
The iodide concentrating activity of the thyroid gland is essential to the production of thyroid hormone and also provides a mechanism for the treatment of thyroid cancer by radioiodine ablation. We report here the nucleotide and amino acid sequence of the human sodium iodide symporter (hNIS), which mediates the iodide uptake activity in the thyroid ...
P A, Smanik, Q, Liu, T L, Furminger, K, Ryu, S, Xing, E L, Mazzaferri, S M, Jhiang   +6 more
openaire   +2 more sources

Sodium Iodide Symporter in Thyroid Carcinoma

2012
Thyroid iodide uptake is essential for the clinical application of radioiodine in patients with well-differentiated thyroid carcinoma. Iodide uptake occurs across the plasma membranes of thyroid follicular cells and cancer cells via an active transporter process mediated by sodium iodide symporter (NIS).
openaire   +1 more source

Sodium Iodide Symporter in the Fight Against Thyroid Cancer

Future Oncology, 2013
n radioiodide n signal transduction inhibitor n sodium iodide symporter n thyroid cancer More than 60 years of experience of radioiodide therapy has indicated its usefulness for the treatment of differentiated thyroid cancer. This therapy utilizes the differentiated function of thyroid cells, namely iodide uptake for thyroid hormone synthesis.
openaire   +2 more sources

Visualisation of sodium-iodide symporter

European Journal of Nuclear Medicine and Molecular Imaging, 2005
Montserrat, Estorch, Luis, de Andres, Valle, Camacho, Jordi, Fuertes, Ato, Rodriguez, Albert, Flotats, Ignasi, Carrio   +6 more
openaire   +2 more sources

Fundamentals, status and promise of sodium-based batteries

Nature Reviews Materials, 2021
Robert E Usiskin, Yaxiang Lu, Jelena Popovic   +2 more
exaly  

Recycling of sodium-ion batteries

Nature Reviews Materials, 2023
Yun Zhao, Naser Tavajohi Hassan Kiadeh
exaly  

The sodium iodide symporter and thyroid disease

Clinical Endocrinology, 2002
Peter P A, Smyth, Roisin M, Dwyer
openaire   +2 more sources