Results 71 to 80 of about 5,659 (220)

Wild-Type P53 Induces Sodium/Iodide Symporter Expression Allowing Radioiodide Therapy in Anaplastic Thyroid Cancer

open access: yesCellular Physiology and Biochemistry, 2017
Aims: Anaplastic thyroid cancer(ATC) is one of the most aggressive solid tumors. Mutations in the p53 gene are common in anaplastic thyroid cancer, but the effects of p53 mutations are yet to be elucidated.
Lin Liu   +8 more
doaj   +1 more source

Hypoxia Inhibitor Improves Iodine Uptake Disorder in Thyroid Cancer Through the hsa_circ_0023990/miR‐448/DNMT1/NIS Axis

open access: yesCancer Science, Volume 116, Issue 8, Page 2113-2124, August 2025.
Our study reveals that hypoxia inhibitors ameliorate iodine uptake dysfunction in thyroid cancer by acting on the hsa_circ_0023990/miR‐448/DNMT1/NIS signaling pathway. ABSTRACT This research seeks to investigate how hypoxia inhibitors enhance iodine uptake in thyroid cancer cells. Clinical samples were gathered and assessed for hsa_circ_0023990, DNMT1,
Ruiqin Gou   +5 more
wiley   +1 more source

The Allele Distribution for the rs7250346 SNP in SLC5A5 among Saudis

open access: yesInternational Journal of Medical Students, 2015
Background: The sodium/iodide cotransporter solute carrier family 5 member 5 (SLC5A5) is found in the basolateral cell membrane of thyroid follicular epithelial cells as a sodium iodide symporter.
Abdullah T. Eissa
doaj   +1 more source

Genomics‐assisted breeding for designing salinity‐smart future crops

open access: yesPlant Biotechnology Journal, Volume 23, Issue 8, Page 3119-3151, August 2025.
This review explores fast‐forward genomics‐assisted breeding tools to fast‐track the designing of salinity‐smart crops. Integration of various breeding tools can enhance salinity tolerance, ensuring sustainable agriculture and global food security. Summary Climate change induces many abiotic stresses, including soil salinity, significantly challenging ...
Ali Raza   +6 more
wiley   +1 more source

Decreased Expression of Thyroglobulin and Sodium Iodide Symporter Genes in Hashimoto’s Thyroiditis

open access: yesInternational Journal of Endocrinology, 2014
Aim. The aim of the study was to compare the expression of sodium iodide symporter (NIS), thyroglobulin (Tg), tumor necrosis factor-α (TNFα), and interleukin-1β genes in patients with Hashimoto’s thyroiditis (HT) and healthy individuals.
Anna Popławska-Kita   +11 more
doaj   +1 more source

Preemptive iodide treatment in the event of a nuclear disaster: The prepper's guide to the galaxy

open access: yes
Experimental Physiology, Volume 110, Issue 12, Page 1771-1776, December 1, 2025.
Per Karkov Cramon   +2 more
wiley   +1 more source

Mechanistic Aspects of Inflammation and Oxidative Stress and Their Association With Thyroid Cancer Risk

open access: yesCancer Medicine, Volume 14, Issue 13, July 2025.
ABSTRACT Aim To investigate the mechanistic aspects of inflammation and oxidative stress and their association with thyroid cancer risk. Methods We have systematically searched the PubMed and Web of Science databases to perform a comprehensive analysis of the pathogenic mechanisms that link obesity, inflammation, and oxidative stress to thyroid cancer.
Bo‐Tao Zhang   +4 more
wiley   +1 more source

Effect of progestin on thyroid function in female Wistar rats

open access: yesFrontiers in Endocrinology
IntroductionTo characterize the influence of female-specific hormones on women’s thyroid function, the study investigated the influence of extra progestin from oral contraceptives on inducing thyroid dysfunction.MethodsSixty female Wistar rats were ...
Honglei Xie   +14 more
doaj   +1 more source

Sodium Iodide Symporter PET and BLI Noninvasively Reveal Mesoangioblast Survival in Dystrophic Mice

open access: yesStem Cell Reports, 2015
Muscular dystrophies are a heterogeneous group of myopathies, characterized by muscle weakness and degeneration, without curative treatment. Mesoangioblasts (MABs) have been proposed as a potential regenerative therapy.
Bryan Holvoet   +10 more
doaj   +1 more source

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