Results 81 to 90 of about 22,958 (276)

Rat Sodium Iodide Symporter for Radioiodide Therapy of Cancer [PDF]

open access: yesClinical Cancer Research, 2004
Abstract Design and development of new approaches for targeted radiotherapy of cancer and improvement of therapeutic index by more local radiation therapy are very important issues. Adenovirus-mediated delivery of the sodium iodide symporter (NIS) gene to cancer cells is a powerful technique to concentrate lethal radiation in tumor cells
Charles J. Link   +7 more
openaire   +3 more sources

Development and characterisation of improved unifocal primary mouse lung cancer models with metastatic potential

open access: yesThe Journal of Pathology, EarlyView.
Abstract Lung cancer is the leading cause of cancer‐related death globally. To better understand the biology of lung cancer, mouse models have been developed using either tail vein‐injected tumour cell lines or genetically modified mice. The current gold‐standard models typically present with multiple lung foci.
Ana‐Rita Pedrosa   +20 more
wiley   +1 more source

Lacrimal duct obstruction after radioiodine therapy: case report and treatment [PDF]

open access: yes, 2014
Iodotherapy represents the radioactive iodine therapy. The beta radiation emitted by radioactive iodine are particles that will be stored in the thyroid tissue destroying cancer cells that were left after surgery (thyroidectomy).
Lorena, Silvia Helena Tavares   +1 more
core   +3 more sources

Hubungan Ekspresi Sodium Iodide Symporter dengan Varian Histopatologi dan Stadium Papillary Thyroid Carcinoma

open access: yesMajalah Kedokteran Andalas
Abstrak                                                               Tujuan:  Mengetahui hubungan ekspresi sodium iodide symporter dengan varian histopatologi dan stadium papillary thyroid carcinoma.
Rini Purnama Sari   +5 more
doaj   +1 more source

Real-time imaging of myoblast transplantation using the human sodium iodide symporter

open access: yesBioTechniques, 2005
The quantification of the graft success is a key element to evaluate the efficiency of cellular therapies for several pathologies such as Duchenne muscular dystrophy. This study describes an approach to evaluate the success of myoblast transplantation (i.
Manaf Bouchentouf   +5 more
doaj   +1 more source

Hypoxia Inhibitor Improves Iodine Uptake Disorder in Thyroid Cancer Through the hsa_circ_0023990/miR‐448/DNMT1/NIS Axis

open access: yesCancer Science, EarlyView.
Our study reveals that hypoxia inhibitors ameliorate iodine uptake dysfunction in thyroid cancer by acting on the hsa_circ_0023990/miR‐448/DNMT1/NIS signaling pathway. ABSTRACT This research seeks to investigate how hypoxia inhibitors enhance iodine uptake in thyroid cancer cells. Clinical samples were gathered and assessed for hsa_circ_0023990, DNMT1,
Ruiqin Gou   +5 more
wiley   +1 more source

Anti-thyroid antibodies: methodological aspects and diagnostic significance [PDF]

open access: yes, 2003
Since the first publication, more than 40 years ago, laboratory tests for the presence of antibodies (Ab) to thyroid antigens (Ag) have played a pivotal position in the diagnosis of thyroid diseases.
Hauache, Omar M.   +3 more
core   +3 more sources

Genomics‐assisted breeding for designing salinity‐smart future crops

open access: yesPlant Biotechnology Journal, EarlyView.
This review explores fast‐forward genomics‐assisted breeding tools to fast‐track the designing of salinity‐smart crops. Integration of various breeding tools can enhance salinity tolerance, ensuring sustainable agriculture and global food security. Summary Climate change induces many abiotic stresses, including soil salinity, significantly challenging ...
Ali Raza   +6 more
wiley   +1 more source

Sodium Iodide Symporter and the Radioiodine Treatment of Thyroid Carcinoma [PDF]

open access: yesNuclear Medicine and Molecular Imaging, 2010
Since the specific accumulation of iodide in thyroid was found in 1915, radioiodine has been widely applied to diagnose and treat thyroid cancer. Iodide uptake occurs across the membrane of the thyroid follicular cells and cancer cells through an active transporter process mediated by the sodium iodide symporter (NIS).
Ho-Young Lee   +4 more
openaire   +3 more sources

Anoctamin 1 is Apically Expressed on Thyroid Follicular Cells and Contributes to ATP- and Calcium-Activated Iodide Efflux

open access: yesCellular Physiology and Biochemistry, 2014
Background/Aims: Iodide efflux from thyroid cells into the follicular lumen is essential for the synthesis of thyroid hormones, however, the pathways mediating this transport have only been partially identified.
Carmela Iosco   +10 more
doaj   +1 more source

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