Background: Electroconvulsive therapy (ECT) is usually given to people with severe depression which has not responded to other forms of treatment such as anti-depressants.
Behzad Nazemroaya, Elham Babaei
doaj +2 more sources
Comparison of recovery duration of Propofol and Thiopental Sodium in ECT
Background and objective: Thiopental sodium is not and ideal intravenous drug for inducing general anesthesia and compared to intravenous anesthetic drugs like propofol has a long standing recovery time.
H Ale Reza +5 more
doaj +1 more source
Evaluation of the Sedative Activity of Naringenin: In Vivo Study with Pharmacokinetics and Molecular Docking Insights [PDF]
This research is designed to investigate the sedative effects of naringenin (NAR) and diazepam against thiopental sodium‐induced sleeping mice. NAR (5 and 10 mg kg), diazepam (DZP) (2 mg kg), flumazenil (FLN) (0.1 mg kg), and their combinations are ...
Dipu Bishwas +8 more
doaj +2 more sources
Comparison of the effect of thiopental sodium-midazolam combination on the hemodynamic response between tracheal intubation and laryngeal mask airway insertion: A clinical trial study [PDF]
Background and Aim: The purpose of this study was to compare the effect of thiopental sodium-midazolam combination on the stress response and hemodynamic changes between tracheal intubation and laryngeal mask airway insertion during airway management ...
Hamidreza Shetabi +3 more
doaj +2 more sources
Objective: One of the most important duties of an anesthetist is keeping the airways open. Since there is a contraindication of succinylcholine in some cases, tracheal intubation is done by non-depolarization muscle relaxants with a delay of 4 min.
M Matloub, SM Rabiei, M Mir
doaj +1 more source
L-Quebrachitol Enhances Sedative Effect of Diazepam Through GABAergic Pathway: Animal and Computational Studies. [PDF]
L‐quebrachitol (LQL) significantly enhanced the sedative effects of diazepam in thiopental sodium‐induced chicks by reducing sleep latency and prolonging duration. Molecular docking revealed LQL's interaction with GABAA receptor (α1 and β2 subunits), supporting a GABAergic mechanism and highlighting its potential as a safe, natural sedative agent ...
Asrafi A +9 more
europepmc +2 more sources
Valproic Acid-Induced Autistic-Like Behavior Is Accompanied by Intestinal Damage Driving Changes in Gut Permeability in a Sex-Dependent Way in Rats. [PDF]
Exposure to valproic acid (VPA) caused sex‐dependent changes in the gut–brain axis, with more pronounced effects in males, including intestinal barrier dysfunction, blood–brain barrier (BBB) impairment, and social behavior deficits. Females showed intestinal inflammation and increased vascular permeability in the ileum, but no behavioral or intestinal ...
Longo B +14 more
europepmc +2 more sources
This work evaluates solid lipid nanoparticles of thiopental sodium against obesity-induced cardiac dysfunction and hypertrophy and explores the possible mechanism of action.
Canzhan Zhu +7 more
doaj +1 more source
Schistosoma mansoni: effects of anesthetics and antimonial drugs on worm shift in the mouse
Mice experimentally infected with Schistosoma mansoni were injected with sodium thiopental or sodium antimonyl gluconate (Triostib R), or submitted to halothane inhalation, with or without a previous injection of thiopental.
José Renan da Cunha-Melo +1 more
doaj +1 more source
ANALYSIS OF OPTIONS FOR THE INDUCTION OF ANESTHESIA FOR CAESAREAN SECTION
Purpose: to compare the depth of anesthesia and hemodynamic reactions during general anesthesia for caesarean section.Materials and Methods: 45 pregnant women scheduled for caesarean section under general anesthesia were enrolled.
A. N. Biryukov +4 more
doaj +1 more source

